BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

472 related articles for article (PubMed ID: 28854261)

  • 1. Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs).
    Wang L; Zhang Y; Wang W; Zhu Y; Chen Y; Tian B
    PLoS One; 2017; 12(8):e0184110. PubMed ID: 28854261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.
    Asuthkar S; Stepanova V; Lebedeva T; Holterman AL; Estes N; Cines DB; Rao JS; Gondi CS
    Mol Biol Cell; 2013 Sep; 24(17):2620-32. PubMed ID: 23864708
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway.
    Yang H; Fan S; An Y; Wang X; Pan Y; Xiaokaiti Y; Duan J; Li X; Tie L; Ye M; Li X
    Oncotarget; 2016 Dec; 7(50):83641-83656. PubMed ID: 27845899
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-200c overexpression inhibits chemoresistance, invasion and colony formation of human pancreatic cancer stem cells.
    Ma C; Huang T; Ding YC; Yu W; Wang Q; Meng B; Luo SX
    Int J Clin Exp Pathol; 2015; 8(6):6533-9. PubMed ID: 26261532
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer.
    Thakur PC; Miller-Ocuin JL; Nguyen K; Matsuda R; Singhi AD; Zeh HJ; Bahary N
    J Transl Med; 2018 Jul; 16(1):190. PubMed ID: 29986726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells.
    Kumar S; Inigo JR; Kumar R; Chaudhary AK; O'Malley J; Balachandar S; Wang J; Attwood K; Yadav N; Hochwald S; Wang X; Chandra D
    Cancer Lett; 2018 Jan; 413():82-93. PubMed ID: 29107110
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells.
    Clarke WR; Amundadottir L; James MA
    Int J Cancer; 2019 Mar; 144(6):1367-1378. PubMed ID: 30468251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine.
    Fiorini C; Cordani M; Padroni C; Blandino G; Di Agostino S; Donadelli M
    Biochim Biophys Acta; 2015 Jan; 1853(1):89-100. PubMed ID: 25311384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling.
    Zhang Z; Han H; Rong Y; Zhu K; Zhu Z; Tang Z; Xiong C; Tao J
    J Exp Clin Cancer Res; 2018 Nov; 37(1):291. PubMed ID: 30486896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review.
    Garcia-Carbonero N; Li W; Cabeza-Morales M; Martinez-Useros J; Garcia-Foncillas J
    Int J Mol Sci; 2018 Aug; 19(9):. PubMed ID: 30134550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resveratrol enhances the chemotherapeutic response and reverses the stemness induced by gemcitabine in pancreatic cancer cells via targeting SREBP1.
    Zhou C; Qian W; Ma J; Cheng L; Jiang Z; Yan B; Li J; Duan W; Sun L; Cao J; Wang F; Wu E; Wu Z; Ma Q; Li X
    Cell Prolif; 2019 Jan; 52(1):e12514. PubMed ID: 30341797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Depletion of pro-oncogenic RUNX2 enhances gemcitabine (GEM) sensitivity of p53-mutated pancreatic cancer Panc-1 cells through the induction of pro-apoptotic TAp63.
    Ozaki T; Nakamura M; Ogata T; Sang M; Yoda H; Hiraoka K; Sang M; Shimozato O
    Oncotarget; 2016 Nov; 7(44):71937-71950. PubMed ID: 27713122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress.
    Cheng S; Swanson K; Eliaz I; McClintick JN; Sandusky GE; Sliva D
    PLoS One; 2015; 10(4):e0122270. PubMed ID: 25915041
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
    Hong X; Li ZX; Hou J; Zhang HY; Zhang CY; Zhang J; Sun H; Pang LH; Wang T; Deng ZH
    BMC Cancer; 2021 Jan; 21(1):33. PubMed ID: 33413231
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro Study of the Antagonistic Effect of Low-dose Liquiritigenin on Gemcitabine-induced Capillary Leak Syndrome in Pancreatic Adenocarcinoma via Inhibiting ROS- Mediated Signalling Pathways.
    Wu W; Xia Q; Luo RJ; Lin ZQ; Xue P
    Asian Pac J Cancer Prev; 2015; 16(10):4369-76. PubMed ID: 26028101
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine.
    Yang MC; Wang HC; Hou YC; Tung HL; Chiu TJ; Shan YS
    Mol Cancer; 2015 Oct; 14():179. PubMed ID: 26458814
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TIMP1 down-regulation enhances gemcitabine sensitivity and reverses chemoresistance in pancreatic cancer.
    Tan Y; Li X; Tian Z; Chen S; Zou J; Lian G; Chen S; Huang K; Chen Y
    Biochem Pharmacol; 2021 Jul; 189():114085. PubMed ID: 32522594
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion.
    Sumiyoshi H; Matsushita A; Nakamura Y; Matsuda Y; Ishiwata T; Naito Z; Uchida E
    Oncol Rep; 2016 Jun; 35(6):3216-26. PubMed ID: 27035235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs.
    Cheng X; Kim JY; Ghafoory S; Duvaci T; Rafiee R; Theobald J; Alborzinia H; Holenya P; Fredebohm J; Merz KH; Mehrabi A; Hafezi M; Saffari A; Eisenbrand G; Hoheisel JD; Wölfl S
    Mol Oncol; 2016 Jun; 10(6):806-24. PubMed ID: 26887594
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and Clinical Significance of Pancreatic Cancer Stem Cells and Their Chemotherapeutic Drug Resistance.
    Kuo YC; Kou HW; Hsu CP; Lo CH; Hwang TL
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108495
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.