BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 28859974)

  • 1. Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function.
    Sampaio EP; Ding L; Rose SR; Cruz P; Hsu AP; Kashyap A; Rosen LB; Smelkinson M; Tavella TA; Ferre EMN; Wierman MK; Zerbe CS; Lionakis MS; Holland SM
    J Allergy Clin Immunol; 2018 May; 141(5):1844-1853.e2. PubMed ID: 28859974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib.
    Al Shehri T; Gilmour K; Gothe F; Loughlin S; Bibi S; Rowan AD; Grainger A; Mohanadas T; Cant AJ; Slatter MA; Hambleton S; Lilic D; Leahy TR
    J Clin Immunol; 2019 Nov; 39(8):776-785. PubMed ID: 31512162
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a distinct subset of disease-associated gain-of-function missense mutations in the STAT1 coiled-coil domain as system mutants.
    Petersen J; Staab J; Bader O; Buhl T; Ivetic A; Meyer T
    Mol Immunol; 2019 Oct; 114():30-40. PubMed ID: 31336247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small Ubiquitin-like Modifier Alters IFN Response.
    Maarifi G; Maroui MA; Dutrieux J; Dianoux L; Nisole S; Chelbi-Alix MK
    J Immunol; 2015 Sep; 195(5):2312-24. PubMed ID: 26223657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The pathogenic T387A missense mutation in the gene encoding signal transducer and activator of transcription 1 exhibits a differential gene expression profile.
    Staab J; Schwämmle T; Meyer T
    Mol Immunol; 2020 Dec; 128():79-88. PubMed ID: 33096415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PIAS proteins promote SUMO-1 conjugation to STAT1.
    Ungureanu D; Vanhatupa S; Kotaja N; Yang J; Aittomaki S; Jänne OA; Palvimo JJ; Silvennoinen O
    Blood; 2003 Nov; 102(9):3311-3. PubMed ID: 12855578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SUMO-1 conjugation selectively modulates STAT1-mediated gene responses.
    Ungureanu D; Vanhatupa S; Grönholm J; Palvimo JJ; Silvennoinen O
    Blood; 2005 Jul; 106(1):224-6. PubMed ID: 15761017
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis.
    Sampaio EP; Hsu AP; Pechacek J; Bax HI; Dias DL; Paulson ML; Chandrasekaran P; Rosen LB; Carvalho DS; Ding L; Vinh DC; Browne SK; Datta S; Milner JD; Kuhns DB; Long Priel DA; Sadat MA; Shiloh M; De Marco B; Alvares M; Gillman JW; Ramarathnam V; de la Morena M; Bezrodnik L; Moreira I; Uzel G; Johnson D; Spalding C; Zerbe CS; Wiley H; Greenberg DE; Hoover SE; Rosenzweig SD; Galgiani JN; Holland SM
    J Allergy Clin Immunol; 2013 Jun; 131(6):1624-34. PubMed ID: 23541320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation.
    Bloomfield M; Kanderová V; Paračková Z; Vrabcová P; Svatoň M; Froňková E; Fejtková M; Zachová R; Rataj M; Zentsová I; Milota T; Klocperk A; Kalina T; Šedivá A
    J Clin Immunol; 2018 Jul; 38(5):589-601. PubMed ID: 29934865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired natural killer cell functions in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.
    Tabellini G; Vairo D; Scomodon O; Tamassia N; Ferraro RM; Patrizi O; Gasperini S; Soresina A; Giardino G; Pignata C; Lougaris V; Plebani A; Dotta L; Cassatella MA; Parolini S; Badolato R
    J Allergy Clin Immunol; 2017 Aug; 140(2):553-564.e4. PubMed ID: 28069426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of the Ebola Virus VP24 Protein by SUMO.
    Vidal S; El Motiam A; Seoane R; Preitakaite V; Bouzaher YH; Gómez-Medina S; San Martín C; Rodríguez D; Rejas MT; Baz-Martínez M; Barrio R; Sutherland JD; Rodríguez MS; Muñoz-Fontela C; Rivas C
    J Virol; 2019 Dec; 94(1):. PubMed ID: 31597768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1.
    Grönholm J; Vanhatupa S; Ungureanu D; Väliaho J; Laitinen T; Valjakka J; Silvennoinen O
    BMC Biochem; 2012 Oct; 13():20. PubMed ID: 23043228
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MAPK-induced Ser727 phosphorylation promotes SUMOylation of STAT1.
    Vanhatupa S; Ungureanu D; Paakkunainen M; Silvennoinen O
    Biochem J; 2008 Jan; 409(1):179-85. PubMed ID: 17897103
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis.
    Arito M; Horiba T; Hachimura S; Inoue J; Sato R
    J Biol Chem; 2008 May; 283(22):15224-31. PubMed ID: 18403372
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional analysis of two STAT1 gain-of-function mutations in two Iranian families with autosomal dominant chronic mucocutaneous candidiasis.
    Ostadi V; Sherkat R; Migaud M; Modaressadeghi SM; Casanova JL; Puel A; Nekooie-Marnany N; Ganjalikhani-Hakemi M
    Med Mycol; 2021 Feb; 59(2):180-188. PubMed ID: 32526033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SUMO-1 controls the protein stability and the biological function of phosducin.
    Klenk C; Humrich J; Quitterer U; Lohse MJ
    J Biol Chem; 2006 Mar; 281(13):8357-64. PubMed ID: 16421094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel gain-of-function STAT1 mutation resulting in basal phosphorylation of STAT1 and increased distal IFN-γ-mediated responses in chronic mucocutaneous candidiasis.
    Martinez-Martinez L; Martinez-Saavedra MT; Fuentes-Prior P; Barnadas M; Rubiales MV; Noda J; Badell I; Rodríguez-Gallego C; de la Calle-Martin O
    Mol Immunol; 2015 Dec; 68(2 Pt C):597-605. PubMed ID: 26514428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small ubiquitin-like modifier (SUMO) modification of zinc finger protein 131 potentiates its negative effect on estrogen signaling.
    Oh Y; Chung KC
    J Biol Chem; 2012 May; 287(21):17517-17529. PubMed ID: 22467880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-MYC-interacting protein enhances type II interferon signaling by inhibiting STAT1 sumoylation.
    Feng L; Li W; Li X; Li X; Ran Y; Yang X; Deng Z; Li H
    FASEB J; 2023 Dec; 37(12):e23281. PubMed ID: 37933920
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation.
    Weinacht KG; Charbonnier LM; Alroqi F; Plant A; Qiao Q; Wu H; Ma C; Torgerson TR; Rosenzweig SD; Fleisher TA; Notarangelo LD; Hanson IC; Forbes LR; Chatila TA
    J Allergy Clin Immunol; 2017 May; 139(5):1629-1640.e2. PubMed ID: 28139313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.