BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 28865132)

  • 1. Growth Rate Changes in CHO Host Cells Are Associated with Karyotypic Heterogeneity.
    Baik JY; Lee KH
    Biotechnol J; 2018 Mar; 13(3):e1700230. PubMed ID: 28865132
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A framework to quantify karyotype variation associated with CHO cell line instability at a single-cell level.
    Baik JY; Lee KH
    Biotechnol Bioeng; 2017 May; 114(5):1045-1053. PubMed ID: 27922175
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chinese hamster ovary cell line DXB-11: chromosomal instability and karyotype heterogeneity.
    Turilova VI; Goryachaya TS; Yakovleva TK
    Mol Cytogenet; 2021 Feb; 14(1):11. PubMed ID: 33596973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Changes in Chromosome Counts and Patterns in CHO Cell Lines upon Generation of Recombinant Cell Lines and Subcloning.
    Vcelar S; Melcher M; Auer N; Hrdina A; Puklowski A; Leisch F; Jadhav V; Wenger T; Baumann M; Borth N
    Biotechnol J; 2018 Mar; 13(3):e1700495. PubMed ID: 29328552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting.
    Vcelar S; Jadhav V; Melcher M; Auer N; Hrdina A; Sagmeister R; Heffner K; Puklowski A; Betenbaugh M; Wenger T; Leisch F; Baumann M; Borth N
    Biotechnol Bioeng; 2018 Jan; 115(1):165-173. PubMed ID: 28921524
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased recombinant protein production owing to expanded opportunities for vector integration in high chromosome number Chinese hamster ovary cells.
    Yamano N; Takahashi M; Ali Haghparast SM; Onitsuka M; Kumamoto T; Frank J; Omasa T
    J Biosci Bioeng; 2016 Aug; 122(2):226-31. PubMed ID: 26850366
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells.
    Spahn PN; Zhang X; Hu Q; Lu H; Hamaker NK; Hefzi H; Li S; Kuo CC; Huang Y; Lee JC; Davis AJ; Ly P; Lee KH; Lewis NE
    Biotechnol Bioeng; 2022 Mar; 119(3):963-982. PubMed ID: 34953085
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones.
    Yamano-Adachi N; Hata H; Nakanishi Y; Omasa T
    J Biosci Bioeng; 2024 Jan; 137(1):54-63. PubMed ID: 37981489
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Karyotypic structure of Chinese hamster clone cell populations in prolonged culture].
    Polianskaia GG; Abramian DS; Glebov OK
    Tsitologiia; 1981 Jul; 23(7):818-30. PubMed ID: 7281231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recurring genomic structural variation leads to clonal instability and loss of productivity.
    Bandyopadhyay AA; O'Brien SA; Zhao L; Fu HY; Vishwanathan N; Hu WS
    Biotechnol Bioeng; 2019 Jan; 116(1):41-53. PubMed ID: 30144379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Instability of CHO chromosomes containing interstitial telomeric sequences originating from Chinese hamster chromosome 10.
    Slijepcevic P; Xiao Y; Natarajan AT; Bryant PE
    Cytogenet Cell Genet; 1997; 76(1-2):58-60. PubMed ID: 9154129
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [COMPARATIVE CYTOGENETIC ANALYSIS OF MONOLAYER AND SUSPENSION CHINESE HAMSTER OVARY CELL LINES CHO(dhfr-)].
    Stefanova VN; Yartseva NM; Petrov AV
    Tsitologiia; 2015; 57(7):491-8. PubMed ID: 26591061
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.
    Chen K; Li D; Li H; Li B; Li J; Huang L; Li R; Xu X; Jiang L; Jiang C; Gu H; Fang J
    Appl Microbiol Biotechnol; 2017 Jul; 101(14):5785-5797. PubMed ID: 28540426
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antibody expression stability in CHO clonally derived cell lines and their subclones: Role of methylation in phenotypic and epigenetic heterogeneity.
    Patel NA; Anderson CR; Terkildsen SE; Davis RC; Pack LD; Bhargava S; Clarke HRG
    Biotechnol Prog; 2018 May; 34(3):635-649. PubMed ID: 29717549
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells.
    Orellana CA; Marcellin E; Palfreyman RW; Munro TP; Gray PP; Nielsen LK
    Biotechnol J; 2018 Mar; 13(3):e1700231. PubMed ID: 29316330
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.
    Veith N; Ziehr H; MacLeod RA; Reamon-Buettner SM
    BMC Biotechnol; 2016 Jan; 16():6. PubMed ID: 26800878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
    Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.
    Ko P; Misaghi S; Hu Z; Zhan D; Tsukuda J; Yim M; Sanford M; Shaw D; Shiratori M; Snedecor B; Laird M; Shen A
    Biotechnol Prog; 2018 May; 34(3):624-634. PubMed ID: 29226566
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA Double-Strand Breaks Affect Chromosomal Rearrangements during Methotrexate-Mediated Gene Amplification in Chinese Hamster Ovary Cells.
    Baik JY; Han HJ; Lee KH
    Pharmaceutics; 2021 Mar; 13(3):. PubMed ID: 33809068
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prediction of CHO cell line stability using expression of DNA repair genes.
    Cordova LT; Dahodwala H; Cooley R; Lee KH
    Biotechnol J; 2024 Jan; 19(1):e2300425. PubMed ID: 37970758
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.