BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 28869600)

  • 1. FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.
    Rupp M; Hagenbuchner J; Rass B; Fiegl H; Kiechl-Kohlendorfer U; Obexer P; Ausserlechner MJ
    Oncogene; 2017 Nov; 36(44):6190-6203. PubMed ID: 28869600
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma.
    Salcher S; Spoden G; Hagenbuchner J; Führer S; Kaserer T; Tollinger M; Huber-Cantonati P; Gruber T; Schuster D; Gust R; Zwierzina H; Müller T; Kiechl-Kohlendorfer U; Ausserlechner MJ; Obexer P
    Oncogene; 2020 Jan; 39(5):1080-1097. PubMed ID: 31591479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.
    Hagenbuchner J; Kuznetsov A; Hermann M; Hausott B; Obexer P; Ausserlechner MJ
    J Cell Sci; 2012 Mar; 125(Pt 5):1191-203. PubMed ID: 22349704
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma.
    Geiger K; Hagenbuchner J; Rupp M; Fiegl H; Sergi C; Meister B; Kiechl-Kohlendorfer U; Müller T; Ausserlechner MJ; Obexer P
    Mol Biol Cell; 2012 Jun; 23(11):2226-34. PubMed ID: 22493319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma.
    Hagenbuchner J; Rupp M; Salvador C; Meister B; Kiechl-Kohlendorfer U; Müller T; Geiger K; Sergi C; Obexer P; Ausserlechner MJ
    Oncotarget; 2016 Nov; 7(47):77591-77606. PubMed ID: 27769056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells.
    Salcher S; Spoden G; Huber JM; Golderer G; Lindner H; Ausserlechner MJ; Kiechl-Kohlendorfer U; Geiger K; Obexer P
    Cells; 2019 Dec; 9(1):. PubMed ID: 31861249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase SIRT6 regulates chemosensitivity in liver cancer cells via modulation of FOXO3 activity.
    Hu JQ; Deng F; Hu XP; Zhang W; Zeng XC; Tian XF
    Oncol Rep; 2018 Dec; 40(6):3635-3644. PubMed ID: 30542728
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells.
    Wildey GM; Howe PH
    J Biol Chem; 2009 Jul; 284(30):20227-39. PubMed ID: 19494111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy.
    Salcher S; Hermann M; Kiechl-Kohlendorfer U; Ausserlechner MJ; Obexer P
    Mol Cancer; 2017 May; 16(1):95. PubMed ID: 28545464
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulating FOXO3 transcriptional activity by small, DBD-binding molecules.
    Hagenbuchner J; Obsilova V; Kaserer T; Kaiser N; Rass B; Psenakova K; Docekal V; Alblova M; Kohoutova K; Schuster D; Aneichyk T; Vesely J; Obexer P; Obsil T; Ausserlechner MJ
    Elife; 2019 Dec; 8():. PubMed ID: 31789593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma.
    Salcher S; Hagenbuchner J; Geiger K; Seiter MA; Rainer J; Kofler R; Hermann M; Kiechl-Kohlendorfer U; Ausserlechner MJ; Obexer P
    Mol Cancer; 2014 Sep; 13():224. PubMed ID: 25261981
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis.
    Obexer P; Hagenbuchner J; Unterkircher T; Sachsenmaier N; Seifarth C; Böck G; Porto V; Geiger K; Ausserlechner M
    Mol Biol Cell; 2009 Apr; 20(7):2041-8. PubMed ID: 19211844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways.
    Cheng J; Fan YH; Xu X; Zhang H; Dou J; Tang Y; Zhong X; Rojas Y; Yu Y; Zhao Y; Vasudevan SA; Zhang H; Nuchtern JG; Kim ES; Chen X; Lu F; Yang J
    Cell Death Dis; 2014 Feb; 5(2):e1079. PubMed ID: 24556694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.
    Lu J; Guan S; Zhao Y; Yu Y; Wang Y; Shi Y; Mao X; Yang KL; Sun W; Xu X; Yi JS; Yang T; Yang J; Nuchtern JG
    Oncotarget; 2016 Dec; 7(50):82757-82769. PubMed ID: 27764791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
    Nalluri S; Peirce SK; Tanos R; Abdella HA; Karmali D; Hogarty MD; Goldsmith KC
    Cancer Biol Ther; 2015; 16(2):276-86. PubMed ID: 25756510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WIP1 phosphatase as a potential therapeutic target in neuroblastoma.
    Richter M; Dayaram T; Gilmartin AG; Ganji G; Pemmasani SK; Van Der Key H; Shohet JM; Donehower LA; Kumar R
    PLoS One; 2015; 10(2):e0115635. PubMed ID: 25658463
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P53/PUMA are potential targets that mediate the protection of brain-derived neurotrophic factor (BDNF)/TrkB from etoposide-induced cell death in neuroblastoma (NB).
    Hua Z; Zhan Y; Zhang S; Dong Y; Jiang M; Tan F; Liu Z; Thiele CJ; Li Z
    Apoptosis; 2018 Aug; 23(7-8):408-419. PubMed ID: 29959561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate.
    Davila D; Connolly NM; Bonner H; Weisová P; Dussmann H; Concannon CG; Huber HJ; Prehn JH
    Cell Death Differ; 2012 Oct; 19(10):1677-88. PubMed ID: 22539004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.
    Van Maerken T; Ferdinande L; Taildeman J; Lambertz I; Yigit N; Vercruysse L; Rihani A; Michaelis M; Cinatl J; Cuvelier CA; Marine JC; De Paepe A; Bracke M; Speleman F; Vandesompele J
    J Natl Cancer Inst; 2009 Nov; 101(22):1562-74. PubMed ID: 19903807
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.
    Dreidax D; Gogolin S; Schroeder C; Muth D; Brueckner LM; Hess EM; Zapatka M; Theißen J; Fischer M; Ehemann V; Schwab M; Savelyeva L; Westermann F
    Hum Mol Genet; 2013 May; 22(9):1735-45. PubMed ID: 23343716
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.