BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 28874583)

  • 41. Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.
    Smart NG; Apelqvist AA; Gu X; Harmon EB; Topper JN; MacDonald RJ; Kim SK
    PLoS Biol; 2006 Feb; 4(2):e39. PubMed ID: 16435884
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-beta-dependent signaling but affects Smad7-dependent transcriptional activation.
    Pulaski L; Landström M; Heldin CH; Souchelnytskyi S
    J Biol Chem; 2001 Apr; 276(17):14344-9. PubMed ID: 11278814
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Expression and function of Smad7 in autoimmune and inflammatory diseases.
    Hu Y; He J; He L; Xu B; Wang Q
    J Mol Med (Berl); 2021 Sep; 99(9):1209-1220. PubMed ID: 34059951
    [TBL] [Abstract][Full Text] [Related]  

  • 44. MicroRNA-21 induces breast cancer cell invasion and migration by suppressing smad7 via EGF and TGF-β pathways.
    Han M; Wang F; Gu Y; Pei X; Guo G; Yu C; Li L; Zhu M; Xiong Y; Wang Y
    Oncol Rep; 2016 Jan; 35(1):73-80. PubMed ID: 26531758
    [TBL] [Abstract][Full Text] [Related]  

  • 45. LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells.
    Kong X; Yan K; Deng P; Fu H; Sun H; Huang W; Jiang S; Dai J; Zhang QC; Liu JG; Xi Q
    Nucleic Acids Res; 2022 Oct; 50(18):10526-10543. PubMed ID: 36134711
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.
    Ruwanpura SM; McLeod L; Miller A; Jones J; Vlahos R; Ramm G; Longano A; Bardin PG; Bozinovski S; Anderson GP; Jenkins BJ
    Am J Physiol Lung Cell Mol Physiol; 2012 Apr; 302(7):L627-39. PubMed ID: 22268122
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Cytokine signalling in embryonic stem cells.
    Kristensen DM; Kalisz M; Nielsen JH
    APMIS; 2005; 113(11-12):756-72. PubMed ID: 16480448
    [TBL] [Abstract][Full Text] [Related]  

  • 48. TGF-β signaling is activated in patients with chronic HBV infection and repressed by SMAD7 overexpression after successful antiviral treatment.
    Argentou N; Germanidis G; Hytiroglou P; Apostolou E; Vassiliadis T; Patsiaoura K; Sideras P; Germenis AE; Speletas M
    Inflamm Res; 2016 May; 65(5):355-65. PubMed ID: 26856334
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Arginine methylation of SMAD7 by PRMT1 in TGF-β-induced epithelial-mesenchymal transition and epithelial stem-cell generation.
    Katsuno Y; Qin J; Oses-Prieto J; Wang H; Jackson-Weaver O; Zhang T; Lamouille S; Wu J; Burlingame A; Xu J; Derynck R
    J Biol Chem; 2018 Aug; 293(34):13059-13072. PubMed ID: 29907569
    [TBL] [Abstract][Full Text] [Related]  

  • 50. LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells.
    Dahéron L; Opitz SL; Zaehres H; Lensch MW; Andrews PW; Itskovitz-Eldor J; Daley GQ
    Stem Cells; 2004; 22(5):770-8. PubMed ID: 15342941
    [TBL] [Abstract][Full Text] [Related]  

  • 51. VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation.
    Li Y; Cui C; Xie F; Kiełbasa S; Mei H; van Dinther M; van Dam H; Bauer A; Zhang L; Ten Dijke P
    J Mol Cell Biol; 2020 Feb; 12(2):138-151. PubMed ID: 31291647
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55.
    Wang H; Song K; Krebs TL; Yang J; Danielpour D
    Oncogene; 2008 Nov; 27(54):6791-805. PubMed ID: 18762808
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The phosphatidylinositol 3-kinase/Akt pathway regulates transforming growth factor-{beta} signaling by destabilizing ski and inducing Smad7.
    Band AM; Björklund M; Laiho M
    J Biol Chem; 2009 Dec; 284(51):35441-9. PubMed ID: 19875456
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Structural basis for inhibitory effects of Smad7 on TGF-β family signaling.
    Murayama K; Kato-Murayama M; Itoh Y; Miyazono K; Miyazawa K; Shirouzu M
    J Struct Biol; 2020 Dec; 212(3):107661. PubMed ID: 33166654
    [TBL] [Abstract][Full Text] [Related]  

  • 55. SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent I CaL, [Ca2+]i transient, and APD increase in cardiomyocytes.
    Hagiwara Y; Miyoshi S; Fukuda K; Nishiyama N; Ikegami Y; Tanimoto K; Murata M; Takahashi E; Shimoda K; Hirano T; Mitamura H; Ogawa S
    J Mol Cell Cardiol; 2007 Dec; 43(6):710-6. PubMed ID: 17961593
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Zinc Chloride Transiently Maintains Mouse Embryonic Stem Cell Pluripotency by Activating Stat3 Signaling.
    Hu J; Yang Z; Wang J; Yu J; Guo J; Liu S; Qian C; Song L; Wu Y; Cheng J
    PLoS One; 2016; 11(2):e0148994. PubMed ID: 26910359
    [TBL] [Abstract][Full Text] [Related]  

  • 57. SMAD7: a timer of tumor progression targeting TGF-β signaling.
    Luo L; Li N; Lv N; Huang D
    Tumour Biol; 2014 Sep; 35(9):8379-85. PubMed ID: 24935472
    [TBL] [Abstract][Full Text] [Related]  

  • 58. The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3.
    Ernst M; Novak U; Nicholson SE; Layton JE; Dunn AR
    J Biol Chem; 1999 Apr; 274(14):9729-37. PubMed ID: 10092661
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation.
    Zhang S; Fei T; Zhang L; Zhang R; Chen F; Ning Y; Han Y; Feng XH; Meng A; Chen YG
    Mol Cell Biol; 2007 Jun; 27(12):4488-99. PubMed ID: 17438144
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase.
    Zhou L; McMahon C; Bhagat T; Alencar C; Yu Y; Fazzari M; Sohal D; Heuck C; Gundabolu K; Ng C; Mo Y; Shen W; Wickrema A; Kong G; Friedman E; Sokol L; Mantzaris I; Pellagatti A; Boultwood J; Platanias LC; Steidl U; Yan L; Yingling JM; Lahn MM; List A; Bitzer M; Verma A
    Cancer Res; 2011 Feb; 71(3):955-63. PubMed ID: 21189329
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.