189 related articles for article (PubMed ID: 28878020)
1. Lipid stress inhibits endocytosis of melanocortin-4 receptor from modified clathrin-enriched sites and impairs receptor desensitization.
Cooney KA; Molden BM; Kowalczyk NS; Russell S; Baldini G
J Biol Chem; 2017 Oct; 292(43):17731-17745. PubMed ID: 28878020
[TBL] [Abstract][Full Text] [Related]
2. Constitutive traffic of melanocortin-4 receptor in Neuro2A cells and immortalized hypothalamic neurons.
Mohammad S; Baldini G; Granell S; Narducci P; Martelli AM; Baldini G
J Biol Chem; 2007 Feb; 282(7):4963-4974. PubMed ID: 17166828
[TBL] [Abstract][Full Text] [Related]
3. Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).
McDaniel FK; Molden BM; Mohammad S; Baldini G; McPike L; Narducci P; Granell S; Baldini G
J Biol Chem; 2012 Jun; 287(26):21873-90. PubMed ID: 22544740
[TBL] [Abstract][Full Text] [Related]
4. Hypothalamic C2-domain protein involved in MC4R trafficking and control of energy balance.
Gavini CK; Cook TM; Rademacher DJ; Mansuy-Aubert V
Metabolism; 2020 Jan; 102():153990. PubMed ID: 31666192
[TBL] [Abstract][Full Text] [Related]
5. Agonist-dependent internalization of the human melanocortin-4 receptors in human embryonic kidney 293 cells.
Gao Z; Lei D; Welch J; Le K; Lin J; Leng S; Duhl D
J Pharmacol Exp Ther; 2003 Dec; 307(3):870-7. PubMed ID: 14534363
[TBL] [Abstract][Full Text] [Related]
6. Exposure of MC4R to agonist in the endoplasmic reticulum stabilizes an active conformation of the receptor that does not desensitize.
Granell S; Molden BM; Baldini G
Proc Natl Acad Sci U S A; 2013 Dec; 110(49):E4733-42. PubMed ID: 24248383
[TBL] [Abstract][Full Text] [Related]
7. Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.
Shinyama H; Masuzaki H; Fang H; Flier JS
Endocrinology; 2003 Apr; 144(4):1301-14. PubMed ID: 12639913
[TBL] [Abstract][Full Text] [Related]
8. Mild lipid stress induces profound loss of MC4R protein abundance and function.
Cragle FK; Baldini G
Mol Endocrinol; 2014 Mar; 28(3):357-67. PubMed ID: 24506538
[TBL] [Abstract][Full Text] [Related]
9. Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation.
Brouwers B; de Oliveira EM; Marti-Solano M; Monteiro FBF; Laurin SA; Keogh JM; Henning E; Bounds R; Daly CA; Houston S; Ayinampudi V; Wasiluk N; Clarke D; Plouffe B; Bouvier M; Babu MM; Farooqi IS; Mokrosiński J
Cell Rep; 2021 Mar; 34(12):108862. PubMed ID: 33761344
[TBL] [Abstract][Full Text] [Related]
10. Obesity-linked variants of melanocortin-4 receptor are misfolded in the endoplasmic reticulum and can be rescued to the cell surface by a chemical chaperone.
Granell S; Mohammad S; Ramanagoudr-Bhojappa R; Baldini G
Mol Endocrinol; 2010 Sep; 24(9):1805-21. PubMed ID: 20631012
[TBL] [Abstract][Full Text] [Related]
11. Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis.
Scarselli M; Donaldson JG
J Biol Chem; 2009 Feb; 284(6):3577-85. PubMed ID: 19033440
[TBL] [Abstract][Full Text] [Related]
12. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C
J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963
[TBL] [Abstract][Full Text] [Related]
13. Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.
Navaroli DM; Bellvé KD; Standley C; Lifshitz LM; Cardia J; Lambright D; Leonard D; Fogarty KE; Corvera S
Proc Natl Acad Sci U S A; 2012 Feb; 109(8):E471-80. PubMed ID: 22308388
[TBL] [Abstract][Full Text] [Related]
14. Melanocortin pathways: suppressed and stimulated melanocortin-4 receptor (MC4R).
Hainer V; Aldhoon Hainerová I; Kunešová M; Taxová Braunerová R; Zamrazilová H; Bendlová B
Physiol Res; 2020 Sep; 69(Suppl 2):S245-S254. PubMed ID: 33094623
[TBL] [Abstract][Full Text] [Related]
15. Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.
Overton JD; Leibel RL
J Biol Chem; 2011 May; 286(21):18914-29. PubMed ID: 21460229
[TBL] [Abstract][Full Text] [Related]
16. Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone.
Tan HY; Steyn FJ; Huang L; Cowley M; Veldhuis JD; Chen C
J Physiol; 2016 Dec; 594(24):7309-7326. PubMed ID: 27558671
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.
René P; Le Gouill C; Pogozheva ID; Lee G; Mosberg HI; Farooqi IS; Valenzano KJ; Bouvier M
J Pharmacol Exp Ther; 2010 Dec; 335(3):520-32. PubMed ID: 20826565
[TBL] [Abstract][Full Text] [Related]
18. The MC4 receptor and control of appetite.
Adan RA; Tiesjema B; Hillebrand JJ; la Fleur SE; Kas MJ; de Krom M
Br J Pharmacol; 2006 Dec; 149(7):815-27. PubMed ID: 17043670
[TBL] [Abstract][Full Text] [Related]
19. Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants.
Sharma S; Thibodeau S; Lytton J
Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165835. PubMed ID: 32423884
[TBL] [Abstract][Full Text] [Related]
20. Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.
Bolze F; Rink N; Brumm H; Kühn R; Mocek S; Schwarz AE; Kless C; Biebermann H; Wurst W; Rozman J; Klingenspor M
Pharmacogenomics J; 2013 Feb; 13(1):80-93. PubMed ID: 21969101
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]