These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 28884166)

  • 41. DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores.
    Sugiura Y; Shiraki T; Konishi M; Oki T
    Proc Natl Acad Sci U S A; 1990 May; 87(10):3831-5. PubMed ID: 2339123
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Identification of active site residues implies a two-step catalytic mechanism for acyl-ACP thioesterase.
    Jing F; Yandeau-Nelson MD; Nikolau BJ
    Biochem J; 2018 Dec; 475(23):3861-3873. PubMed ID: 30409825
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Evidence for a novel phosphopantetheinyl transferase domain in the polyketide synthase for enediyne biosynthesis.
    Murugan E; Liang ZX
    FEBS Lett; 2008 Apr; 582(7):1097-103. PubMed ID: 18319060
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Identification of a nonaketide product for the iterative polyketide synthase in biosynthesis of the nine-membered enediyne C-1027.
    Chen X; Guo ZF; Lai PM; Sze KH; Guo Z
    Angew Chem Int Ed Engl; 2010 Oct; 49(43):7926-8. PubMed ID: 20848627
    [No Abstract]   [Full Text] [Related]  

  • 45. Characterization of an Anthracene Intermediate in Dynemicin Biosynthesis.
    Cohen DR; Townsend CA
    Angew Chem Int Ed Engl; 2018 May; 57(20):5650-5654. PubMed ID: 29512267
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates.
    Van Lanen SG; Dorrestein PC; Christenson SD; Liu W; Ju J; Kelleher NL; Shen B
    J Am Chem Soc; 2005 Aug; 127(33):11594-5. PubMed ID: 16104723
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
    Chang CY; Lohman JR; Cao H; Tan K; Rudolf JD; Ma M; Xu W; Bingman CA; Yennamalli RM; Bigelow L; Babnigg G; Yan X; Joachimiak A; Phillips GN; Shen B
    Biochemistry; 2016 Sep; 55(36):5142-54. PubMed ID: 27560143
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.
    Luo Y; Lin S; Zhang J; Cooke HA; Bruner SD; Shen B
    J Biol Chem; 2008 May; 283(21):14694-702. PubMed ID: 18387946
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
    Argyropoulos P; Bergeret F; Pardin C; Reimer JM; Pinto A; Boddy CN; Schmeing TM
    Biochim Biophys Acta; 2016 Mar; 1860(3):486-97. PubMed ID: 26592346
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Cyclic enediyne-amino acid chimeras as new aminopeptidase N inhibitors.
    Gredičak M; Abramić M; Jerić I
    Amino Acids; 2012 Nov; 43(5):2087-100. PubMed ID: 22526243
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Solution structure of the calicheamicin gamma 1I-DNA complex.
    Kumar RA; Ikemoto N; Patel DJ
    J Mol Biol; 1997 Jan; 265(2):187-201. PubMed ID: 9020982
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Natural product inspired design of enediyne prodrugs via rearrangement of an allylic double bond.
    Dai WM
    Curr Med Chem; 2003 Nov; 10(21):2265-83. PubMed ID: 14529342
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.
    Tsai SC; Lu H; Cane DE; Khosla C; Stroud RM
    Biochemistry; 2002 Oct; 41(42):12598-606. PubMed ID: 12379102
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Relative Reactivity of Benzothiophene-Fused Enediynes in the Bergman Cyclization.
    Lyapunova AG; Danilkina NA; Rumyantsev AM; Khlebnikov AF; Chislov MV; Starova GL; Sambuk EV; Govdi AI; Bräse S; Balova IA
    J Org Chem; 2018 Mar; 83(5):2788-2801. PubMed ID: 29402088
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.
    Tsai SC; Miercke LJ; Krucinski J; Gokhale R; Chen JC; Foster PG; Cane DE; Khosla C; Stroud RM
    Proc Natl Acad Sci U S A; 2001 Dec; 98(26):14808-13. PubMed ID: 11752428
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
    Chen S; Xue Y; Sherman DH; Reynolds KA
    Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Deciphering the pathway-specific regulatory network for production of ten-membered enediyne Tiancimycins in Streptomyces sp. CB03234-S.
    Zhu M; Zhang F; Gan T; Lin J; Duan Y; Zhu X
    Microb Cell Fact; 2022 Sep; 21(1):188. PubMed ID: 36088456
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structural insight into the self-sacrifice mechanism of enediyne resistance.
    Singh S; Hager MH; Zhang C; Griffith BR; Lee MS; Hallenga K; Markley JL; Thorson JS
    ACS Chem Biol; 2006 Aug; 1(7):451-60. PubMed ID: 17168523
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.
    Shen B; Hindra ; Yan X; Huang T; Ge H; Yang D; Teng Q; Rudolf JD; Lohman JR
    Bioorg Med Chem Lett; 2015 Jan; 25(1):9-15. PubMed ID: 25434000
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Pathway Retrofitting Yields Insights into the Biosynthesis of Anthraquinone-Fused Enediynes.
    Ma GL; Tran HT; Low ZJ; Candra H; Pang LM; Cheang QW; Fang M; Liang ZX
    J Am Chem Soc; 2021 Aug; 143(30):11500-11509. PubMed ID: 34293863
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.