These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 2888621)

  • 1. Phencyclidine iminium ion. NADPH-dependent metabolism, covalent binding to macromolecules, and inactivation of cytochrome(s) P-450.
    Hoag MK; Trevor AJ; Kalir A; Castagnoli N
    Drug Metab Dispos; 1987; 15(4):485-90. PubMed ID: 2888621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism-dependent inactivation of liver microsomal enzymes by phencyclidine.
    Hoag MK; Trevor AJ; Asscher Y; Weissman J; Castagnoli N
    Drug Metab Dispos; 1984; 12(3):371-5. PubMed ID: 6145566
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism-based inactivation of rat liver cytochrome P4502B1 by phencyclidine and its oxidative product, the iminium ion.
    Crowley JR; Hollenberg PF
    Drug Metab Dispos; 1995 Aug; 23(8):786-93. PubMed ID: 7493543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism of phencyclidine. The role of iminium ion formation in covalent binding to rabbit microsomal protein.
    Ward DP; Trevor AJ; Kalir A; Adams JD; Baillie TA; Castagnoli N
    Drug Metab Dispos; 1982; 10(6):690-5. PubMed ID: 6130925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective mechanism-based inactivation of the major phenobarbital-inducible P-450 cytochrome from rabbit liver by phencyclidine and its oxidation product, the iminium compound.
    Osawa Y; Coon MJ
    Drug Metab Dispos; 1989; 17(1):7-13. PubMed ID: 2566474
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung.
    Williams DE; Shigenaga MK; Castagnoli N
    Drug Metab Dispos; 1990; 18(4):418-28. PubMed ID: 1976062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism-dependent covalent binding of (S)-[5-3H]nicotine to liver and lung microsomal macromolecules.
    Shigenaga MK; Trevor AJ; Castagnoli N
    Drug Metab Dispos; 1988; 16(3):397-402. PubMed ID: 2900731
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of phencyclidine by human liver microsomes.
    Laurenzana EM; Owens SM
    Drug Metab Dispos; 1997 May; 25(5):557-63. PubMed ID: 9152594
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS
    Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: evidence for the formation of a novel quinone methide intermediate.
    Driscoll JP; Kornecki K; Wolkowski JP; Chupak L; Kalgutkar AS; O'Donnell JP
    Chem Res Toxicol; 2007 Oct; 20(10):1488-97. PubMed ID: 17892269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Masubuchi Y; Igarashi S; Suzuki T; Horie T; Narimatsu S
    J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic inactivation of cytochrome P4502B1 by phencyclidine: immunochemical and radiochemical analyses of the protective effects of glutathione.
    Sharma U; Roberts ES; Kent UM; Owens SM; Hollenberg PF
    Drug Metab Dispos; 1997 Feb; 25(2):243-50. PubMed ID: 9029055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A; Parkinson A
    Drug Metab Dispos; 1996 Dec; 24(12):1307-13. PubMed ID: 8971135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biotransformation of phencyclidine.
    Holsztynska EJ; Domino EF
    Drug Metab Rev; 1985-1986; 16(3):285-320. PubMed ID: 3914938
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rates of phencyclidine metabolism by the isolated perfused lung, lung microsomes, and liver microsomes of rabbits.
    Law FC
    Drug Metab Dispos; 1982; 10(4):361-5. PubMed ID: 6126335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ; Webb CD; Yao M; Weedon AC; Bend JR
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.
    Voorman RL; Maio SM; Payne NA; Zhao Z; Koeplinger KA; Wang X
    J Pharmacol Exp Ther; 1998 Oct; 287(1):381-8. PubMed ID: 9765359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic polymorphism of cytochrome P-450-dependent phencyclidine hydroxylation in mice. Comparison of phencyclidine hydroxylation in humans.
    Holsztynska EJ; Weber WW; Domino EF
    Drug Metab Dispos; 1991; 19(1):48-53. PubMed ID: 1673421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dose- and time-dependent changes in phencyclidine metabolite covalent binding in rats and the possible role of CYP2D1.
    Owens SM; Gunnell M; Laurenzana EM; Valentine JL
    J Pharmacol Exp Ther; 1993 Jun; 265(3):1261-6. PubMed ID: 8510006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism for isaxonine hepatitis. I. Metabolic activation by mouse and human cytochrome P-450.
    Lettéron P; Fouin-Fortunet H; Tinel M; Danan G; Belghiti J; Pessayre D
    J Pharmacol Exp Ther; 1984 Jun; 229(3):845-50. PubMed ID: 6547179
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.