229 related articles for article (PubMed ID: 28887460)
1. Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach.
Beccari AR; Gemei M; Lo Monte M; Menegatti N; Fanton M; Pedretti A; Bovolenta S; Nucci C; Molteni A; Rossignoli A; Brandolini L; Taddei A; Za L; Liberati C; Vistoli G
Sci Rep; 2017 Sep; 7(1):10999. PubMed ID: 28887460
[TBL] [Abstract][Full Text] [Related]
2. Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Parks DJ; Parsons WH; Colburn RW; Meegalla SK; Ballentine SK; Illig CR; Qin N; Liu Y; Hutchinson TL; Lubin ML; Stone DJ; Baker JF; Schneider CR; Ma J; Damiano BP; Flores CM; Player MR
J Med Chem; 2011 Jan; 54(1):233-47. PubMed ID: 21128593
[TBL] [Abstract][Full Text] [Related]
3. Optimization of potency and pharmacokinetic properties of tetrahydroisoquinoline transient receptor potential melastatin 8 (TRPM8) antagonists.
Horne DB; Tamayo NA; Bartberger MD; Bo Y; Clarine J; Davis CD; Gore VK; Kaller MR; Lehto SG; Ma VV; Nishimura N; Nguyen TT; Tang P; Wang W; Youngblood BD; Zhang M; Gavva NR; Monenschein H; Norman MH
J Med Chem; 2014 Apr; 57(7):2989-3004. PubMed ID: 24597733
[TBL] [Abstract][Full Text] [Related]
4. Identification of a novel 2-pyridyl-benzensulfonamide derivative, RQ-00203078, as a selective and orally active TRPM8 antagonist.
Ohmi M; Shishido Y; Inoue T; Ando K; Fujiuchi A; Yamada A; Watanabe S; Kawamura K
Bioorg Med Chem Lett; 2014 Dec; 24(23):5364-8. PubMed ID: 25455182
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists.
Kobayashi JI; Hirasawa H; Ozawa T; Ozawa T; Takeda H; Fujimori Y; Nakanishi O; Kamada N; Ikeda T
Bioorg Med Chem; 2017 Jan; 25(2):727-742. PubMed ID: 27964995
[TBL] [Abstract][Full Text] [Related]
6. Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship.
Sherkheli MA; Vogt-Eisele AK; Bura D; Beltrán Márques LR; Gisselmann G; Hatt H
J Pharm Pharm Sci; 2010; 13(2):242-53. PubMed ID: 20816009
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists.
de la Torre-Martínez R; Bonache MA; Llabrés-Campaner PJ; Balsera B; Fernández-Carvajal A; Fernández-Ballester G; Ferrer-Montiel A; Pérez de Vega MJ; González-Muñiz R
Sci Rep; 2017 Sep; 7(1):10766. PubMed ID: 28883526
[TBL] [Abstract][Full Text] [Related]
8. Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists.
Tamayo NA; Bo Y; Gore V; Ma V; Nishimura N; Tang P; Deng H; Klionsky L; Lehto SG; Wang W; Youngblood B; Chen J; Correll TL; Bartberger MD; Gavva NR; Norman MH
J Med Chem; 2012 Feb; 55(4):1593-611. PubMed ID: 22329507
[TBL] [Abstract][Full Text] [Related]
9. Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
Malkia A; Pertusa M; Fernández-Ballester G; Ferrer-Montiel A; Viana F
Mol Pain; 2009 Nov; 5():62. PubMed ID: 19886999
[TBL] [Abstract][Full Text] [Related]
10. In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening.
Iraci N; Ostacolo C; Medina-Peris A; Ciaglia T; Novoselov AM; Altieri A; Cabañero D; Fernandez-Carvajal A; Campiglia P; Gomez-Monterrey I; Bertamino A; Kurkin AV
Int J Mol Sci; 2022 Feb; 23(4):. PubMed ID: 35216186
[TBL] [Abstract][Full Text] [Related]
11. Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.
Zhu B; Xia M; Xu X; Ludovici DW; Tennakoon M; Youngman MA; Matthews JM; Dax SL; Colburn RW; Qin N; Hutchinson TL; Lubin ML; Brandt MR; Stone DJ; Flores CM; Macielag MJ
Bioorg Med Chem Lett; 2013 Apr; 23(7):2234-7. PubMed ID: 23411075
[TBL] [Abstract][Full Text] [Related]
12. TRPM8 biology and medicinal chemistry.
DeFalco J; Duncton MA; Emerling D
Curr Top Med Chem; 2011; 11(17):2237-52. PubMed ID: 21671871
[TBL] [Abstract][Full Text] [Related]
13. KPR-5714, a Novel Transient Receptor Potential Melastatin 8 Antagonist, Improves Overactive Bladder via Inhibition of Bladder Afferent Hyperactivity in Rats.
Nakanishi O; Fujimori Y; Aizawa N; Hayashi T; Matsuzawa A; Kobayashi JI; Hirasawa H; Mutai Y; Tanada F; Igawa Y
J Pharmacol Exp Ther; 2020 May; 373(2):239-247. PubMed ID: 32102918
[TBL] [Abstract][Full Text] [Related]
14. Functional roles of transient receptor potential melastatin 8 (TRPM8) channels in the cold stress-induced detrusor overactivity pathways in conscious rats.
Lei Z; Ishizuka O; Imamura T; Noguchi W; Yamagishi T; Yokoyama H; Kurizaki Y; Sudha GS; Hosoda T; Nishizawa O; Andersson KE
Neurourol Urodyn; 2013 Jun; 32(5):500-4. PubMed ID: 23001687
[TBL] [Abstract][Full Text] [Related]
15. Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer.
Pérez de Vega MJ; Gómez-Monterrey I; Ferrer-Montiel A; González-Muñiz R
J Med Chem; 2016 Nov; 59(22):10006-10029. PubMed ID: 27437828
[TBL] [Abstract][Full Text] [Related]
16. Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activation.
Miller S; Rao S; Wang W; Liu H; Wang J; Gavva NR
PLoS One; 2014; 9(9):e107151. PubMed ID: 25203266
[TBL] [Abstract][Full Text] [Related]
17. Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin.
Selescu T; Ciobanu AC; Dobre C; Reid G; Babes A
Chem Senses; 2013 Sep; 38(7):563-75. PubMed ID: 23828908
[TBL] [Abstract][Full Text] [Related]
18. The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist.
Gardiner JC; Kirkup AJ; Curry J; Humphreys S; O'Regan P; Postlethwaite M; Young KC; Kitching L; Ethell BT; Winpenny D; McMurray G
Eur J Pharmacol; 2014 Oct; 740():398-409. PubMed ID: 25058909
[TBL] [Abstract][Full Text] [Related]
19. Recent Progress in TRPM8 Modulation: An Update.
González-Muñiz R; Bonache MA; Martín-Escura C; Gómez-Monterrey I
Int J Mol Sci; 2019 May; 20(11):. PubMed ID: 31141957
[TBL] [Abstract][Full Text] [Related]
20. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia.
Lehto SG; Weyer AD; Zhang M; Youngblood BD; Wang J; Wang W; Kerstein PC; Davis C; Wild KD; Stucky CL; Gavva NR
Naunyn Schmiedebergs Arch Pharmacol; 2015 Apr; 388(4):465-76. PubMed ID: 25662185
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
