252 related articles for article (PubMed ID: 28888203)
1. Role of glutathione biosynthesis in endothelial dysfunction and fibrosis.
Espinosa-Díez C; Miguel V; Vallejo S; Sánchez FJ; Sandoval E; Blanco E; Cannata P; Peiró C; Sánchez-Ferrer CF; Lamas S
Redox Biol; 2018 Apr; 14():88-99. PubMed ID: 28888203
[TBL] [Abstract][Full Text] [Related]
2. Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis.
Espinosa-Diez C; Fierro-Fernández M; Sánchez-Gómez F; Rodríguez-Pascual F; Alique M; Ruiz-Ortega M; Beraza N; Martínez-Chantar ML; Fernández-Hernando C; Lamas S
Antioxid Redox Signal; 2015 Nov; 23(14):1092-105. PubMed ID: 25353619
[TBL] [Abstract][Full Text] [Related]
3. Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.
Dalton TP; Dieter MZ; Yang Y; Shertzer HG; Nebert DW
Biochem Biophys Res Commun; 2000 Dec; 279(2):324-9. PubMed ID: 11118286
[TBL] [Abstract][Full Text] [Related]
4. Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice.
Weldy CS; Luttrell IP; White CC; Morgan-Stevenson V; Bammler TK; Beyer RP; Afsharinejad Z; Kim F; Chitaley K; Kavanagh TJ
Free Radic Biol Med; 2012 Sep; 53(6):1264-78. PubMed ID: 22824862
[TBL] [Abstract][Full Text] [Related]
5. Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.
Chen Y; Shertzer HG; Schneider SN; Nebert DW; Dalton TP
J Biol Chem; 2005 Oct; 280(40):33766-74. PubMed ID: 16081425
[TBL] [Abstract][Full Text] [Related]
6. Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicity.
Backos DS; Brocker CN; Franklin CC
Toxicol Appl Pharmacol; 2010 Feb; 243(1):35-45. PubMed ID: 19914271
[TBL] [Abstract][Full Text] [Related]
7. Regulation of endothelial glutathione by ICAM-1: implications for inflammation.
Kevil CG; Pruitt H; Kavanagh TJ; Wilkerson J; Farin F; Moellering D; Darley-Usmar VM; Bullard DC; Patel RP
FASEB J; 2004 Aug; 18(11):1321-3. PubMed ID: 15180961
[TBL] [Abstract][Full Text] [Related]
8. Gclc deficiency in mouse CNS causes mitochondrial damage and neurodegeneration.
Feng W; Rosca M; Fan Y; Hu Y; Feng P; Lee HG; Monnier VM; Fan X
Hum Mol Genet; 2017 Apr; 26(7):1376-1390. PubMed ID: 28158580
[TBL] [Abstract][Full Text] [Related]
9. Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.
Cortes-Wanstreet MM; Giedzinski E; Limoli CL; Luderer U
Mutagenesis; 2009 May; 24(3):211-24. PubMed ID: 19153097
[TBL] [Abstract][Full Text] [Related]
10. Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.
Yang Y; Dieter MZ; Chen Y; Shertzer HG; Nebert DW; Dalton TP
J Biol Chem; 2002 Dec; 277(51):49446-52. PubMed ID: 12384496
[TBL] [Abstract][Full Text] [Related]
11. Alterations in glutamate cysteine ligase content in the retina of two retinitis pigmentosa animal models.
Sánchez-Vallejo V; Benlloch-Navarro S; Trachsel-Moncho L; López-Pedrajas R; Almansa I; Romero FJ; Miranda M
Free Radic Biol Med; 2016 Jul; 96():245-54. PubMed ID: 27140233
[TBL] [Abstract][Full Text] [Related]
12. Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate-cysteine ligase subunits.
Sikalidis AK; Mazor KM; Lee JI; Roman HB; Hirschberger LL; Stipanuk MH
Amino Acids; 2014 May; 46(5):1285-96. PubMed ID: 24557597
[TBL] [Abstract][Full Text] [Related]
13. Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits.
Willis MN; Liu Y; Biterova EI; Simpson MA; Kim H; Lee J; Barycki JJ
Biochemistry; 2011 Jul; 50(29):6508-17. PubMed ID: 21657237
[TBL] [Abstract][Full Text] [Related]
14. Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis.
Mohar I; Botta D; White CC; McConnachie LA; Kavanagh TJ
Curr Protoc Toxicol; 2009 Feb; Chapter 6():Unit6.16. PubMed ID: 23045016
[TBL] [Abstract][Full Text] [Related]
15. Activation of promoter activity of the catalytic subunit of γ-glutamylcysteine ligase (GCL) in brain endothelial cells by insulin requires antioxidant response element 4 and altered glycemic status: implication for GCL expression and GSH synthesis.
Langston JW; Li W; Harrison L; Aw TY
Free Radic Biol Med; 2011 Nov; 51(9):1749-57. PubMed ID: 21871559
[TBL] [Abstract][Full Text] [Related]
16. Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.
Krzywanski DM; Dickinson DA; Iles KE; Wigley AF; Franklin CC; Liu RM; Kavanagh TJ; Forman HJ
Arch Biochem Biophys; 2004 Mar; 423(1):116-25. PubMed ID: 14871475
[TBL] [Abstract][Full Text] [Related]
17. Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.
Thompson JA; White CC; Cox DP; Chan JY; Kavanagh TJ; Fausto N; Franklin CC
Free Radic Biol Med; 2009 Jun; 46(12):1614-25. PubMed ID: 19328227
[TBL] [Abstract][Full Text] [Related]
18. Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: alterations in the activities and protein expression of glutathione-related enzymes.
Gu F; Chauhan V; Chauhan A
Free Radic Biol Med; 2013 Dec; 65():488-496. PubMed ID: 23892356
[TBL] [Abstract][Full Text] [Related]
19. TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms.
Franklin CC; Rosenfeld-Franklin ME; White C; Kavanagh TJ; Fausto N
FASEB J; 2003 Aug; 17(11):1535-7. PubMed ID: 12824300
[TBL] [Abstract][Full Text] [Related]
20. Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During Larval Development in
Enya S; Yamamoto C; Mizuno H; Esaki T; Lin HK; Iga M; Morohashi K; Hirano Y; Kataoka H; Masujima T; Shimada-Niwa Y; Niwa R
Genetics; 2017 Dec; 207(4):1519-1532. PubMed ID: 29021278
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
