242 related articles for article (PubMed ID: 28892064)
1. A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors.
Neumann JE; Wefers AK; Lambo S; Bianchi E; Bockstaller M; Dorostkar MM; Meister V; Schindler P; Korshunov A; von Hoff K; Nowak J; Warmuth-Metz M; Schneider MR; Renner-Müller I; Merk DJ; Shakarami M; Sharma T; Chavez L; Glass R; Chan JA; Taketo MM; Neumann P; Kool M; Schüller U
Nat Med; 2017 Oct; 23(10):1191-1202. PubMed ID: 28892064
[TBL] [Abstract][Full Text] [Related]
2. A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes.
Spence T; Perotti C; Sin-Chan P; Picard D; Wu W; Singh A; Anderson C; Blough MD; Cairncross JG; Lafay-Cousin L; Strother D; Hawkins C; Narendran A; Huang A; Chan JA
Neuro Oncol; 2014 Jan; 16(1):62-71. PubMed ID: 24311633
[TBL] [Abstract][Full Text] [Related]
3. Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy.
Paret C; Theruvath J; Russo A; Kron B; El Malki K; Lehmann N; Wingerter A; Neu MA; Gerhold-Ay A; Wagner W; Sommer C; Pietsch T; Seidmann L; Faber J
Oncotarget; 2016 Dec; 7(50):83378-83391. PubMed ID: 27825128
[TBL] [Abstract][Full Text] [Related]
4. Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1.
Kerl K; Moreno N; Holsten T; Ahlfeld J; Mertins J; Hotfilder M; Kool M; Bartelheim K; Schleicher S; Handgretinger R; Schüller U; Meisterernst M; Frühwald MC
Int J Cancer; 2014 Aug; 135(4):989-95. PubMed ID: 24420698
[TBL] [Abstract][Full Text] [Related]
5. ETMR: a tumor entity in its infancy.
Lambo S; von Hoff K; Korshunov A; Pfister SM; Kool M
Acta Neuropathol; 2020 Sep; 140(3):249-266. PubMed ID: 32601913
[TBL] [Abstract][Full Text] [Related]
6. GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis.
Srivastava RK; Kaylani SZ; Edrees N; Li C; Talwelkar SS; Xu J; Palle K; Pressey JG; Athar M
Oncotarget; 2014 Dec; 5(23):12151-65. PubMed ID: 25432075
[TBL] [Abstract][Full Text] [Related]
7. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.
Beauchamp EM; Ringer L; Bulut G; Sajwan KP; Hall MD; Lee YC; Peaceman D; Ozdemirli M; Rodriguez O; Macdonald TJ; Albanese C; Toretsky JA; Uren A
J Clin Invest; 2011 Jan; 121(1):148-60. PubMed ID: 21183792
[TBL] [Abstract][Full Text] [Related]
8. Sonic Hedgehog-GLI Family Zinc Finger 1 Signaling Pathway Promotes the Growth and Migration of Pancreatic Cancer Cells by Regulating the Transcription of Eukaryotic Translation Initiation Factor 5A2.
Xu X; Liu H; Zhang H; Dai W; Guo C; Xie C; Wei S; He S; Xu X
Pancreas; 2015 Nov; 44(8):1252-8. PubMed ID: 26465952
[TBL] [Abstract][Full Text] [Related]
9. LIN28A, a sensitive immunohistochemical marker for Embryonal Tumor with Multilayered Rosettes (ETMR), is also positive in a subset of Atypical Teratoid/Rhabdoid Tumor (AT/RT).
Rao S; Rajeswarie RT; Chickabasaviah Yasha T; Nandeesh BN; Arivazhagan A; Santosh V
Childs Nerv Syst; 2017 Nov; 33(11):1953-1959. PubMed ID: 28744687
[TBL] [Abstract][Full Text] [Related]
10. Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
Kangwan N; Kim YJ; Han YM; Jeong M; Park JM; Go EJ; Hahm KB
Oncotarget; 2016 Feb; 7(7):7667-82. PubMed ID: 26716648
[TBL] [Abstract][Full Text] [Related]
11. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
[TBL] [Abstract][Full Text] [Related]
12. LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR).
Korshunov A; Ryzhova M; Jones DT; Northcott PA; van Sluis P; Volckmann R; Koster J; Versteeg R; Cowdrey C; Perry A; Picard D; Rosenblum M; Giangaspero F; Aronica E; Schüller U; Hasselblatt M; Collins VP; von Deimling A; Lichter P; Huang A; Pfister SM; Kool M
Acta Neuropathol; 2012 Dec; 124(6):875-81. PubMed ID: 23161096
[TBL] [Abstract][Full Text] [Related]
13. Brain and Spinal Cord Tumors of Embryonic Origin.
Lampros M; Alexiou GA
Adv Exp Med Biol; 2023; 1405():405-420. PubMed ID: 37452947
[TBL] [Abstract][Full Text] [Related]
14. Metformin suppresses the expression of Sonic hedgehog in gastric cancer cells.
Song Z; Wei B; Lu C; Huang X; Li P; Chen L
Mol Med Rep; 2017 Apr; 15(4):1909-1915. PubMed ID: 28260041
[TBL] [Abstract][Full Text] [Related]
15. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
Arnhold V; Boos J; Lanvers-Kaminsky C
Cancer Chemother Pharmacol; 2016 Mar; 77(3):495-505. PubMed ID: 26781311
[TBL] [Abstract][Full Text] [Related]
16. Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density.
Middelkamp M; Ruck L; Krisp C; Sumisławski P; Mohammadi B; Dottermusch M; Meister V; Küster L; Schlüter H; Windhorst S; Neumann JE
Acta Neuropathol Commun; 2021 Nov; 9(1):185. PubMed ID: 34801069
[TBL] [Abstract][Full Text] [Related]
17. [Mechanisms of arsenic trioxide induced tumor cell apoptosis in myelodysplastic syndrome mice model in vivo].
Lu J; Jin J
Zhonghua Er Ke Za Zhi; 2006 Oct; 44(10):782-6. PubMed ID: 17229386
[TBL] [Abstract][Full Text] [Related]
18. Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma.
Dottermusch M; Sumisławski P; Krevet J; Middelkamp M; Voß H; Siebels B; Bartsch H; Sotlar K; Meyer P; Frank S; Korshunov A; Glatzel M; Schüller U; Neumann JE
Oncogenesis; 2021 Nov; 10(11):78. PubMed ID: 34785636
[TBL] [Abstract][Full Text] [Related]
19. Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
Singh RR; Cho-Vega JH; Davuluri Y; Ma S; Kasbidi F; Milito C; Lennon PA; Drakos E; Medeiros LJ; Luthra R; Vega F
Cancer Res; 2009 Mar; 69(6):2550-8. PubMed ID: 19244133
[TBL] [Abstract][Full Text] [Related]
20. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Kleinman CL; Gerges N; Papillon-Cavanagh S; Sin-Chan P; Pramatarova A; Quang DA; Adoue V; Busche S; Caron M; Djambazian H; Bemmo A; Fontebasso AM; Spence T; Schwartzentruber J; Albrecht S; Hauser P; Garami M; Klekner A; Bognar L; Montes JL; Staffa A; Montpetit A; Berube P; Zakrzewska M; Zakrzewski K; Liberski PP; Dong Z; Siegel PM; Duchaine T; Perotti C; Fleming A; Faury D; Remke M; Gallo M; Dirks P; Taylor MD; Sladek R; Pastinen T; Chan JA; Huang A; Majewski J; Jabado N
Nat Genet; 2014 Jan; 46(1):39-44. PubMed ID: 24316981
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]