BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 28892789)

  • 1. Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.
    Ismail N; Ismail M; Azmi NH; Bakar MFA; Yida Z; Abdullah MA; Basri H
    Biomed Pharmacother; 2017 Nov; 95():780-788. PubMed ID: 28892789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beneficial effects of TQRF and TQ nano- and conventional emulsions on memory deficit, lipid peroxidation, total antioxidant status, antioxidants genes expression and soluble Aβ levels in high fat-cholesterol diet-induced rats.
    Ismail N; Ismail M; Azmi NH; Bakar MFA; Yida Z; Stanslas J; Sani D; Basri H; Abdullah MA
    Chem Biol Interact; 2017 Sep; 275():61-73. PubMed ID: 28734741
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of beta-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer's disease.
    Jaya Prasanthi RP; Schommer E; Thomasson S; Thompson A; Feist G; Ghribi O
    Mech Ageing Dev; 2008 Nov; 129(11):649-55. PubMed ID: 18845178
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
    Tian J; Shi J; Zhang L; Yin J; Hu Q; Xu Y; Sheng S; Wang P; Ren Y; Wang R; Wang Y
    Curr Alzheimer Res; 2009 Apr; 6(2):118-31. PubMed ID: 19355846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
    J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mercury-induced amyloid-beta (Aβ) accumulation in the brain is mediated by disruption of Aβ transport.
    Kim DK; Park JD; Choi BS
    J Toxicol Sci; 2014 Aug; 39(4):625-35. PubMed ID: 25056787
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucocorticoids facilitate astrocytic amyloid-β peptide deposition by increasing the expression of APP and BACE1 and decreasing the expression of amyloid-β-degrading proteases.
    Wang Y; Li M; Tang J; Song M; Xu X; Xiong J; Li J; Bai Y
    Endocrinology; 2011 Jul; 152(7):2704-15. PubMed ID: 21558319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity.
    Fang F; Yu Q; Arancio O; Chen D; Gore SS; Yan SS; Yan SF
    Hum Mol Genet; 2018 Mar; 27(6):1002-1014. PubMed ID: 29329433
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondria are devoid of amyloid β-protein (Aβ)-producing secretases: Evidence for unlikely occurrence within mitochondria of Aβ generation from amyloid precursor protein.
    Mamada N; Tanokashira D; Ishii K; Tamaoka A; Araki W
    Biochem Biophys Res Commun; 2017 Apr; 486(2):321-328. PubMed ID: 28302486
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis.
    Abuelezz SA; Hendawy N
    Life Sci; 2021 May; 273():119310. PubMed ID: 33667517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
    Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
    Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
    J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis.
    Zhao J; O'Connor T; Vassar R
    J Neuroinflammation; 2011 Nov; 8():150. PubMed ID: 22047170
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cystatin C Shifts APP Processing from Amyloid-β Production towards Non-Amyloidgenic Pathway in Brain Endothelial Cells.
    Wang XF; Liu DX; Liang Y; Xing LL; Zhao WH; Qin XX; Shang DS; Li B; Fang WG; Cao L; Zhao WD; Chen YH
    PLoS One; 2016; 11(8):e0161093. PubMed ID: 27532339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Self-assembling nanofibers alter the processing of amyloid precursor protein in a transgenic mouse model of Alzheimer's disease.
    Yang H; Yang H; Xie Z; Wang P; Bi J
    Neurol Res; 2015 Jan; 37(1):84-91. PubMed ID: 25005263
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of High Cholesterol Regulation of LRP1 and RAGE on Aβ Transport Across the Blood-Brain Barrier in Alzheimer's Disease.
    Zhou R; Chen LL; Yang H; Li L; Liu J; Chen L; Hong WJ; Wang CG; Ma JJ; Huang J; Zhou XF; Liu D; Zhou HD
    Curr Alzheimer Res; 2021; 18(5):428-442. PubMed ID: 34488598
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.