200 related articles for article (PubMed ID: 28900796)
1. Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.
Sánchez-Murcia PA; Cortés-Cabrera Á; Gago F
J Comput Aided Mol Des; 2017 Oct; 31(10):915-928. PubMed ID: 28900796
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the binding of didemnins to human elongation factor eEF1A and rationale for the potent antitumor activity of these marine natural products.
Marco E; Martín-Santamaría S; Cuevas C; Gago F
J Med Chem; 2004 Aug; 47(18):4439-52. PubMed ID: 15317456
[TBL] [Abstract][Full Text] [Related]
3. Molecular docking uncovers TSPY binds more efficiently with eEF1A2 compared to eEF1A1.
Panwar D; Rawal L; Ali S
J Biomol Struct Dyn; 2015; 33(7):1412-23. PubMed ID: 25105321
[TBL] [Abstract][Full Text] [Related]
4. Multiple molecular dynamics simulation of the isoforms of human translation elongation factor 1A reveals reversible fluctuations between "open" and "closed" conformations and suggests specific for eEF1A1 affinity for Ca2+-calmodulin.
Kanibolotsky DS; Novosyl'na OV; Abbott CM; Negrutskii BS; El'skaya AV
BMC Struct Biol; 2008 Jan; 8():4. PubMed ID: 18221514
[TBL] [Abstract][Full Text] [Related]
5. Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties.
Krastel P; Roggo S; Schirle M; Ross NT; Perruccio F; Aspesi P; Aust T; Buntin K; Estoppey D; Liechty B; Mapa F; Memmert K; Miller H; Pan X; Riedl R; Thibaut C; Thomas J; Wagner T; Weber E; Xie X; Schmitt EK; Hoepfner D
Angew Chem Int Ed Engl; 2015 Aug; 54(35):10149-54. PubMed ID: 26179970
[TBL] [Abstract][Full Text] [Related]
6. Novel nannocystin A analogues as anticancer therapeutics: Synthesis, biological evaluations and structure-activity relationship studies.
Liu Q; Yang X; Ji J; Zhang SL; He Y
Eur J Med Chem; 2019 May; 170():99-111. PubMed ID: 30878835
[TBL] [Abstract][Full Text] [Related]
7. Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.
Carelli JD; Sethofer SG; Smith GA; Miller HR; Simard JL; Merrick WC; Jain RK; Ross NT; Taunton J
Elife; 2015 Dec; 4():. PubMed ID: 26651998
[TBL] [Abstract][Full Text] [Related]
8. Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF; Carelli JD; Rundlet EJ; Brown A; Shao S; Ferguson A; Wasserman MR; Holm M; Taunton J; Blanchard SC
Elife; 2022 Oct; 11():. PubMed ID: 36264623
[TBL] [Abstract][Full Text] [Related]
9. Translation elongation factor eEF1A1 is a novel partner of a multifunctional protein Sgt1.
Novosylna O; Jurewicz E; Pydiura N; Goral A; Filipek A; Negrutskii B; El'skaya A
Biochimie; 2015 Dec; 119():137-45. PubMed ID: 26545799
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of nannocystin analogues toward understanding the binding role of the (2R,3S)-Epoxide in nannocystin A.
Tian Y; Xu X; Ding Y; Hao X; Bai Y; Tang Y; Zhang X; Li Q; Yang Z; Zhang W; Chen Y
Eur J Med Chem; 2018 Apr; 150():626-632. PubMed ID: 29554614
[TBL] [Abstract][Full Text] [Related]
11. Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.
Soares DC; Barlow PN; Newbery HJ; Porteous DJ; Abbott CM
PLoS One; 2009 Jul; 4(7):e6315. PubMed ID: 19636410
[TBL] [Abstract][Full Text] [Related]
12. Evolutionary importance of translation elongation factor eEF1A variant switching: eEF1A1 down-regulation in muscle is conserved in Xenopus but is controlled at a post-transcriptional level.
Newbery HJ; Stancheva I; Zimmerman LB; Abbott CM
Biochem Biophys Res Commun; 2011 Jul; 411(1):19-24. PubMed ID: 21722626
[TBL] [Abstract][Full Text] [Related]
13. Comparison of the ability of mammalian eEF1A1 and its oncogenic variant eEF1A2 to interact with actin and calmodulin.
Novosylna O; Doyle A; Vlasenko D; Murphy M; Negrutskii B; El'skaya A
Biol Chem; 2017 Jan; 398(1):113-124. PubMed ID: 27483363
[TBL] [Abstract][Full Text] [Related]
14. eEF1A2 and neuronal degeneration.
Abbott CM; Newbery HJ; Squires CE; Brownstein D; Griffiths LA; Soares DC
Biochem Soc Trans; 2009 Dec; 37(Pt 6):1293-7. PubMed ID: 19909265
[TBL] [Abstract][Full Text] [Related]
15. Truncation of the A,A(∗),A' helices segment impairs the actin bundling activity of mammalian eEF1A1.
Vlasenko DO; Novosylna OV; Negrutskii BS; El'skaya AV
FEBS Lett; 2015 May; 589(11):1187-93. PubMed ID: 25862498
[TBL] [Abstract][Full Text] [Related]
16. On the Need to Tell Apart Fraternal Twins eEF1A1 and eEF1A2, and Their Respective Outfits.
Mills A; Gago F
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34203525
[TBL] [Abstract][Full Text] [Related]
17. Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.
Losada A; Muñoz-Alonso MJ; García C; Sánchez-Murcia PA; Martínez-Leal JF; Domínguez JM; Lillo MP; Gago F; Galmarini CM
Sci Rep; 2016 Oct; 6():35100. PubMed ID: 27713531
[TBL] [Abstract][Full Text] [Related]
18. Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.
Davies FCJ; Marshall GF; Pegram E; Gadd D; Abbott CM
Mol Cell Neurosci; 2023 Sep; 126():103879. PubMed ID: 37429391
[TBL] [Abstract][Full Text] [Related]
19. Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells.
Wilson RB; Kozlov AM; Hatam Tehrani H; Twumasi-Ankrah JS; Chen YJ; Borrelli MJ; Sawyez CG; Maini S; Shepherd TG; Cumming RC; Betts DH; Borradaile NM
J Biol Chem; 2024 Mar; 300(3):105684. PubMed ID: 38272231
[TBL] [Abstract][Full Text] [Related]
20. A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules.
Panasyuk G; Nemazanyy I; Filonenko V; Negrutskii B; El'skaya AV
Int J Biochem Cell Biol; 2008; 40(1):63-71. PubMed ID: 17936057
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]