191 related articles for article (PubMed ID: 28906103)
1. Resolving the Atomistic Modes of Anle138b Inhibitory Action on Peptide Oligomer Formation.
Matthes D; Gapsys V; Griesinger C; de Groot BL
ACS Chem Neurosci; 2017 Dec; 8(12):2791-2808. PubMed ID: 28906103
[TBL] [Abstract][Full Text] [Related]
2. Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates.
Deeg AA; Reiner AM; Schmidt F; Schueder F; Ryazanov S; Ruf VC; Giller K; Becker S; Leonov A; Griesinger C; Giese A; Zinth W
Biochim Biophys Acta; 2015 Sep; 1850(9):1884-90. PubMed ID: 26028294
[TBL] [Abstract][Full Text] [Related]
3. An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase.
Matthes D; Gapsys V; Brennecke JT; de Groot BL
Sci Rep; 2016 Sep; 6():33156. PubMed ID: 27616019
[TBL] [Abstract][Full Text] [Related]
4. The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.
Antonschmidt L; Matthes D; Dervişoğlu R; Frieg B; Dienemann C; Leonov A; Nimerovsky E; Sant V; Ryazanov S; Giese A; Schröder GF; Becker S; de Groot BL; Griesinger C; Andreas LB
Nat Commun; 2022 Sep; 13(1):5385. PubMed ID: 36104315
[TBL] [Abstract][Full Text] [Related]
5. Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates.
Reiner AM; Schmidt F; Ryazanov S; Leonov A; Weckbecker D; Deeg AA; Griesinger C; Giese A; Zinth W
Biochim Biophys Acta Gen Subj; 2018 Apr; 1862(4):800-807. PubMed ID: 29273222
[TBL] [Abstract][Full Text] [Related]
6. Atomistic mechanism of polyphenol amyloid aggregation inhibitors: molecular dynamics study of Curcumin, Exifone, and Myricetin interaction with the segment of tau peptide oligomer.
Berhanu WM; Masunov AE
J Biomol Struct Dyn; 2015; 33(7):1399-411. PubMed ID: 25093402
[TBL] [Abstract][Full Text] [Related]
7. Simulation Studies of Amyloidogenic Polypeptides and Their Aggregates.
Ilie IM; Caflisch A
Chem Rev; 2019 Jun; 119(12):6956-6993. PubMed ID: 30973229
[TBL] [Abstract][Full Text] [Related]
8. Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR.
Dervişoğlu R; Antonschmidt L; Nimerovsky E; Sant V; Kim M; Ryazanov S; Leonov A; Fuentes-Monteverde JC; Wegstroth M; Giller K; Mathies G; Giese A; Becker S; Griesinger C; Andreas LB
Methods; 2023 Jun; 214():18-27. PubMed ID: 37037308
[TBL] [Abstract][Full Text] [Related]
9. Understanding amyloid fibril nucleation and aβ oligomer/drug interactions from computer simulations.
Nguyen P; Derreumaux P
Acc Chem Res; 2014 Feb; 47(2):603-11. PubMed ID: 24368046
[TBL] [Abstract][Full Text] [Related]
10. Structural Characterization of Amyloid β17-42 Dimer by Potential of Mean Force Analysis: Insights from Molecular Dynamics Simulations.
Dutta M; Chutia R; Mattaparthi VSK
Protein Pept Lett; 2017; 24(7):650-660. PubMed ID: 28641562
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanism of β-sheet self-organization at water-hydrophobic interfaces.
Nikolic A; Baud S; Rauscher S; Pomès R
Proteins; 2011 Jan; 79(1):1-22. PubMed ID: 20938982
[TBL] [Abstract][Full Text] [Related]
12. Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
Wagner J; Ryazanov S; Leonov A; Levin J; Shi S; Schmidt F; Prix C; Pan-Montojo F; Bertsch U; Mitteregger-Kretzschmar G; Geissen M; Eiden M; Leidel F; Hirschberger T; Deeg AA; Krauth JJ; Zinth W; Tavan P; Pilger J; Zweckstetter M; Frank T; Bähr M; Weishaupt JH; Uhr M; Urlaub H; Teichmann U; Samwer M; Bötzel K; Groschup M; Kretzschmar H; Griesinger C; Giese A
Acta Neuropathol; 2013 Jun; 125(6):795-813. PubMed ID: 23604588
[TBL] [Abstract][Full Text] [Related]
13. Formation of partially ordered oligomers of amyloidogenic hexapeptide (NFGAIL) in aqueous solution observed in molecular dynamics simulations.
Wu C; Lei H; Duan Y
Biophys J; 2004 Nov; 87(5):3000-9. PubMed ID: 15326028
[TBL] [Abstract][Full Text] [Related]
14. Molecular docking analysis of α-Synuclein aggregation with Anle138b.
Grewal A; Sheokand D; Saini V; Kumar A
Bioinformation; 2024; 20(3):217-222. PubMed ID: 38711999
[TBL] [Abstract][Full Text] [Related]
15. Molecular insight into amyloid oligomer destabilizing mechanism of flavonoid derivative 2-(4' benzyloxyphenyl)-3-hydroxy-chromen-4-one through docking and molecular dynamics simulations.
Kumar A; Srivastava S; Tripathi S; Singh SK; Srikrishna S; Sharma A
J Biomol Struct Dyn; 2016 Jun; 34(6):1252-63. PubMed ID: 26208790
[TBL] [Abstract][Full Text] [Related]
16. Driving forces and structural determinants of steric zipper peptide oligomer formation elucidated by atomistic simulations.
Matthes D; Gapsys V; de Groot BL
J Mol Biol; 2012 Aug; 421(2-3):390-416. PubMed ID: 22326493
[TBL] [Abstract][Full Text] [Related]
17. The role of Phe in the formation of well-ordered oligomers of amyloidogenic hexapeptide (NFGAIL) observed in molecular dynamics simulations with explicit solvent.
Wu C; Lei H; Duan Y
Biophys J; 2005 Apr; 88(4):2897-906. PubMed ID: 15653723
[TBL] [Abstract][Full Text] [Related]
18. Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence.
Kellock J; Hopping G; Caughey B; Daggett V
J Mol Biol; 2016 Jun; 428(11):2317-2328. PubMed ID: 27012425
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b.
Hosseini-Gerami L; Ficulle E; Humphryes-Kirilov N; Airey DC; Scherschel J; Kananathan S; Eastwood BJ; Bose S; Collier DA; Laing E; Evans D; Broughton H; Bender A
Alzheimers Res Ther; 2023 Mar; 15(1):52. PubMed ID: 36918909
[TBL] [Abstract][Full Text] [Related]
20. Molecular dynamics simulations and free energy analyses on the dimer formation of an amyloidogenic heptapeptide from human beta2-microglobulin: implication for the protofibril structure.
Lei H; Wu C; Wang Z; Duan Y
J Mol Biol; 2006 Mar; 356(4):1049-63. PubMed ID: 16403526
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
