These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 28910072)

  • 21. Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics.
    Abramyan AM; Slack RD; Meena S; Davis BA; Newman AH; Singh SK; Shi L
    Neuropharmacology; 2019 Dec; 161():107411. PubMed ID: 30391505
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities.
    Sánchez C; Bergqvist PB; Brennum LT; Gupta S; Hogg S; Larsen A; Wiborg O
    Psychopharmacology (Berl); 2003 Jun; 167(4):353-62. PubMed ID: 12719960
    [TBL] [Abstract][Full Text] [Related]  

  • 23. High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions.
    Plenge P; Wiborg O
    Neurosci Lett; 2005 Aug; 383(3):203-8. PubMed ID: 15955412
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Computational characterization of the selective inhibition of human norepinephrine and serotonin transporters by an escitalopram scaffold.
    Zheng G; Yang F; Fu T; Tu G; Chen Y; Yao X; Xue W; Zhu F
    Phys Chem Chem Phys; 2018 Nov; 20(46):29513-29527. PubMed ID: 30457616
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation.
    Rasmussen TN; Plenge P; Bay T; Egebjerg J; Gether U
    Neuropharmacology; 2009 Sep; 57(3):287-94. PubMed ID: 19500602
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Allosteric Binding of MDMA to the Human Serotonin Transporter (hSERT) via Ensemble Binding Space Analysis with ΔG Calculations, Induced Fit Docking and Monte Carlo Simulations.
    Islas ÁA; Scior T
    Molecules; 2022 May; 27(9):. PubMed ID: 35566327
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants.
    Mortensen OV; Kristensen AS; Wiborg O
    J Neurochem; 2001 Oct; 79(2):237-47. PubMed ID: 11677251
    [TBL] [Abstract][Full Text] [Related]  

  • 28. X-ray structure based evaluation of analogs of citalopram: Compounds with increased affinity and selectivity compared with R-citalopram for the allosteric site (S2) on hSERT.
    Topiol S; Bang-Andersen B; Sanchez C; Plenge P; Loland CJ; Juhl K; Larsen K; Bregnedal P; Bøgesø KP
    Bioorg Med Chem Lett; 2017 Feb; 27(3):470-478. PubMed ID: 28041833
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mouse strain differences in SSRI sensitivity correlate with serotonin transporter binding and function.
    Jin ZL; Chen XF; Ran YH; Li XR; Xiong J; Zheng YY; Gao NN; Li YF
    Sci Rep; 2017 Aug; 7(1):8631. PubMed ID: 28819255
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [(11)C]MADAM PET study.
    Finnema SJ; Halldin C; Bang-Andersen B; Bundgaard C; Farde L
    Psychopharmacology (Berl); 2015 Nov; 232(21-22):4159-67. PubMed ID: 25980484
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
    Henry LK; Field JR; Adkins EM; Parnas ML; Vaughan RA; Zou MF; Newman AH; Blakely RD
    J Biol Chem; 2006 Jan; 281(4):2012-23. PubMed ID: 16272152
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter.
    Plenge P; Abramyan AM; Sørensen G; Mørk A; Weikop P; Gether U; Bang-Andersen B; Shi L; Loland CJ
    Nat Commun; 2020 Mar; 11(1):1491. PubMed ID: 32198394
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Substrate and Inhibitor-Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry.
    Söderhielm PC; Andersen J; Munro L; Nielsen AT; Kristensen AS
    Mol Pharmacol; 2015 Oct; 88(4):676-88. PubMed ID: 26174773
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain.
    Gradisch R; Szöllősi D; Niello M; Lazzarin E; Sitte HH; Stockner T
    J Biol Chem; 2022 Mar; 298(3):101613. PubMed ID: 35065961
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine.
    Owens MJ; Knight DL; Nemeroff CB
    Biol Psychiatry; 2001 Sep; 50(5):345-50. PubMed ID: 11543737
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A Photoswitchable Inhibitor of the Human Serotonin Transporter.
    Cheng B; Morstein J; Ladefoged LK; Maesen JB; Schiøtt B; Sinning S; Trauner D
    ACS Chem Neurosci; 2020 May; 11(9):1231-1237. PubMed ID: 32275382
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.
    Cozzi NV; Gopalakrishnan A; Anderson LL; Feih JT; Shulgin AT; Daley PF; Ruoho AE
    J Neural Transm (Vienna); 2009 Dec; 116(12):1591-9. PubMed ID: 19756361
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Time-course of serotonin transporter occupancy by single dose of three SSRIs in human brain: A positron emission tomography study with [(11)C]DASB.
    Arakawa R; Tateno A; Kim W; Sakayori T; Ogawa K; Okubo Y
    Psychiatry Res Neuroimaging; 2016 May; 251():1-6. PubMed ID: 27082864
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Escitalopram, an antidepressant with an allosteric effect at the serotonin transporter--a review of current understanding of its mechanism of action.
    Zhong H; Haddjeri N; Sánchez C
    Psychopharmacology (Berl); 2012 Jan; 219(1):1-13. PubMed ID: 21901317
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dynamic extracellular vestibule of human SERT: Unveiling druggable potential with high-affinity allosteric inhibitors.
    Salomon K; Abramyan AM; Plenge P; Wang L; Bundgaard C; Bang-Andersen B; Loland CJ; Shi L
    Proc Natl Acad Sci U S A; 2023 Oct; 120(41):e2304089120. PubMed ID: 37792512
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.