BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

397 related articles for article (PubMed ID: 28912885)

  • 1. Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia.
    Oh ET; Kim CW; Kim HG; Lee JS; Park HJ
    Theranostics; 2017; 7(14):3415-3431. PubMed ID: 28912885
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1α and causes cancer cell death under hypoxia.
    Oh ET; Kim CW; Kim SJ; Lee JS; Hong SS; Park HJ
    Sci Rep; 2016 Jun; 6():27382. PubMed ID: 27263528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Brusatol inhibits HIF-1 signaling pathway and suppresses glucose uptake under hypoxic conditions in HCT116 cells.
    Lu Y; Wang B; Shi Q; Wang X; Wang D; Zhu L
    Sci Rep; 2016 Dec; 6():39123. PubMed ID: 27982118
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways.
    Ma J; Li J; Wang KS; Mi C; Piao LX; Xu GH; Li X; Lee JJ; Jin X
    Int Immunopharmacol; 2016 Oct; 39():1-9. PubMed ID: 27394002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
    Lin HC; Su SL; Lu CY; Lin AH; Lin WC; Liu CS; Yang YC; Wang HM; Lii CK; Chen HW
    Environ Toxicol; 2017 Mar; 32(3):918-930. PubMed ID: 27297870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N; Martinez CA; Kerr B; Zaiter SS; Morgan M; McAlpine SR; Cook KM
    Cell Physiol Biochem; 2019; 53(3):480-495. PubMed ID: 31486323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxygen-sensing under the influence of nitric oxide.
    Berchner-Pfannschmidt U; Tug S; Kirsch M; Fandrey J
    Cell Signal; 2010 Mar; 22(3):349-56. PubMed ID: 19861159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.
    Kim TH; Hur EG; Kang SJ; Kim JA; Thapa D; Lee YM; Ku SK; Jung Y; Kwak MK
    Cancer Res; 2011 Mar; 71(6):2260-75. PubMed ID: 21278237
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
    Lee SH; Bae SC; Kim KW; Lee YM
    Oncogene; 2014 Mar; 33(11):1458-67. PubMed ID: 23542169
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.
    Li MY; Mi C; Wang KS; Wang Z; Zuo HX; Piao LX; Xu GH; Li X; Ma J; Jin X
    Chem Biol Interact; 2017 Aug; 274():58-67. PubMed ID: 28684144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity.
    Li YN; Xi MM; Guo Y; Hai CX; Yang WL; Qin XJ
    Toxicol Lett; 2014 Jan; 224(2):165-74. PubMed ID: 24188932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Britannin stabilizes T cell activity and inhibits proliferation and angiogenesis by targeting PD-L1 via abrogation of the crosstalk between Myc and HIF-1α in cancer.
    Zhang YF; Zhang ZH; Li MY; Wang JY; Xing Y; Ri M; Jin CH; Xu GH; Piao LX; Zuo HX; Jin HL; Ma J; Jin X
    Phytomedicine; 2021 Jan; 81():153425. PubMed ID: 33310309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer.
    Sui H; Zhao J; Zhou L; Wen H; Deng W; Li C; Ji Q; Liu X; Feng Y; Chai N; Zhang Q; Cai J; Li Q
    Cancer Lett; 2017 Sep; 403():86-97. PubMed ID: 28602978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.
    Knowles HJ; Tian YM; Mole DR; Harris AL
    Circ Res; 2004 Jul; 95(2):162-9. PubMed ID: 15192023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
    Ban HS; Kim BK; Lee H; Kim HM; Harmalkar D; Nam M; Park SK; Lee K; Park JT; Kim I; Lee K; Hwang GS; Won M
    Cell Death Dis; 2017 Jun; 8(6):e2843. PubMed ID: 28569777
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 15-Deoxy-Δ
    Choi JE; Kim JH; Song NY; Suh J; Kim DH; Kim SJ; Na HK; Nadas J; Dong Z; Cha YN; Surh YJ
    Free Radic Res; 2016 Oct; 50(10):1140-1152. PubMed ID: 27598034
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The SLC34A2-ROS-HIF-1-induced up-regulation of EZH2 expression promotes proliferation and chemo-resistance to apoptosis in colorectal cancer.
    Li X; Xing J; Wang H; Yu E
    Biosci Rep; 2019 May; 39(5):. PubMed ID: 30038060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.
    Koshiji M; Kageyama Y; Pete EA; Horikawa I; Barrett JC; Huang LE
    EMBO J; 2004 May; 23(9):1949-56. PubMed ID: 15071503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. c-Myc is regulated by HIF-2α in chronic hypoxia and influences sensitivity to 5-FU in colon cancer.
    Wang L; Xue M; Chung DC
    Oncotarget; 2016 Nov; 7(48):78910-78917. PubMed ID: 27793037
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.