219 related articles for article (PubMed ID: 28915668)
1. NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.
Narayan S; Jaiswal AS; Sharma R; Nawab A; Duckworth LV; Law BK; Zajac-Kaye M; George TJ; Sharma J; Sharma AK; Hromas RA
Oncotarget; 2017 Aug; 8(34):57246-57264. PubMed ID: 28915668
[TBL] [Abstract][Full Text] [Related]
2. ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
Narayan S; Ramisetti S; Jaiswal AS; Law BK; Singh-Pillay A; Singh P; Amin S; Sharma AK
Eur J Med Chem; 2019 Jan; 161():456-467. PubMed ID: 30384048
[TBL] [Abstract][Full Text] [Related]
3. Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition.
Mani C; Pai S; Papke CM; Palle K; Gmeiner WH
Neoplasia; 2018 Dec; 20(12):1236-1245. PubMed ID: 30439567
[TBL] [Abstract][Full Text] [Related]
4. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
[TBL] [Abstract][Full Text] [Related]
5. Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells.
Paul S; Chatterjee S; Sinha S; Dash SR; Pradhan R; Das B; Goutam K; Kundu CN
Expert Opin Ther Targets; 2023; 27(10):999-1015. PubMed ID: 37787493
[TBL] [Abstract][Full Text] [Related]
6. Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy.
Martino-Echarri E; Henderson BR; Brocardo MG
Oncotarget; 2014 Oct; 5(20):9889-900. PubMed ID: 25301724
[TBL] [Abstract][Full Text] [Related]
7. Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.
Wen C; Chen J; Zhang D; Wang H; Che J; Qin Q; He L; Cai Z; Lin M; Lou Q; Huang L; Chen D; Iwamoto A; Ren D; Wang L; Lan P; Wang J; Liu H; Yang X
Cancer Lett; 2016 Dec; 383(2):295-308. PubMed ID: 27713084
[TBL] [Abstract][Full Text] [Related]
8. Knockdown of DNA-binding protein A enhances the chemotherapy sensitivity of colorectal cancer via suppressing the Wnt/β-catenin/Chk1 pathway.
Tong C; Qu K; Wang G; Liu R; Duan B; Wang X; Liu C
Cell Biol Int; 2020 Oct; 44(10):2075-2085. PubMed ID: 32652867
[TBL] [Abstract][Full Text] [Related]
9. Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A.
Narayan S; Raza A; Mahmud I; Koo N; Garrett TJ; Law ME; Law BK; Sharma AK
iScience; 2022 Jul; 25(7):104518. PubMed ID: 35754740
[TBL] [Abstract][Full Text] [Related]
10. Olaparib-mediated enhancement of 5-fluorouracil cytotoxicity in mismatch repair deficient colorectal cancer cells.
de Castro E Gloria H; Jesuíno Nogueira L; Bencke Grudzinski P; da Costa Ghignatti PV; Guecheva TN; Motta Leguisamo N; Saffi J
BMC Cancer; 2021 Apr; 21(1):448. PubMed ID: 33888065
[TBL] [Abstract][Full Text] [Related]
11. Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase.
McNeely S; Conti C; Sheikh T; Patel H; Zabludoff S; Pommier Y; Schwartz G; Tse A
Cell Cycle; 2010 Mar; 9(5):995-1004. PubMed ID: 20160494
[TBL] [Abstract][Full Text] [Related]
12. XRCC2-Deficient Cells are Highly Sensitive to 5-Fluorouracil in Colorectal Cancer.
Zhang YZ; An JH; Liu YX; Wu XC; Han SS; Ren XQ; Qin CJ
Cell Physiol Biochem; 2017; 43(3):1207-1219. PubMed ID: 28977800
[TBL] [Abstract][Full Text] [Related]
13. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity.
Fujinaka Y; Matsuoka K; Iimori M; Tuul M; Sakasai R; Yoshinaga K; Saeki H; Morita M; Kakeji Y; Gillespie DA; Yamamoto K; Takata M; Kitao H; Maehara Y
DNA Repair (Amst); 2012 Mar; 11(3):247-58. PubMed ID: 22188649
[TBL] [Abstract][Full Text] [Related]
14. Dclk1 Inhibition Cancels 5-FU-induced Cell-cycle Arrest and Decreases Cell Survival in Colorectal Cancer.
Suehiro Y; Takemoto Y; Nishimoto A; Ueno K; Shirasawa B; Tanaka T; Kugimiya N; Suga A; Harada E; Hamano K
Anticancer Res; 2018 Nov; 38(11):6225-6230. PubMed ID: 30396941
[TBL] [Abstract][Full Text] [Related]
15. ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway.
Yang H; Huebner K; Hampel C; Erlenbach-Wuensch K; Selvamani SB; Shukla V; Geppert CI; Hartmann A; Mahadevan V; Schneider-Stock R
BMC Cancer; 2023 May; 23(1):480. PubMed ID: 37237279
[TBL] [Abstract][Full Text] [Related]
16. Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
Li X; Ma Y; Wu J; Ni M; Chen A; Zhou Y; Dai W; Chen Z; Jiang R; Ling Y; Yao Q; Chen W
Drug Resist Updat; 2023 Mar; 67():100930. PubMed ID: 36736043
[TBL] [Abstract][Full Text] [Related]
17. Quinacrine-Mediated Inhibition of Nrf2 Reverses Hypoxia-Induced 5-Fluorouracil Resistance in Colorectal Cancer.
Kim HG; Kim CW; Lee DH; Lee JS; Oh ET; Park HJ
Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31491980
[TBL] [Abstract][Full Text] [Related]
18. Triacanthine enhances the sensitivity of colorectal cancer cells to 5-fluorouracil by regulating RRM2.
Liu YH; Shen MM; Wu YC; Luo KZ; Zhang JK; Wang Z; Chen ZY; Li J; Wu SY; Lin NM; Zhang C; Li YL
Phytomedicine; 2024 Apr; 126():155204. PubMed ID: 38342015
[TBL] [Abstract][Full Text] [Related]
19. Mannose Inhibits the Pentose Phosphate Pathway in Colorectal Cancer and Enhances Sensitivity to 5-Fluorouracil Therapy.
Al Hadeethi S; El-Baba C; Araji K; Hayar B; Cheikh IA; El-Khoury R; Usta J; Darwiche N
Cancers (Basel); 2023 Apr; 15(8):. PubMed ID: 37190196
[TBL] [Abstract][Full Text] [Related]
20. A Bioactive Compound from
Zhang W; Peng C; Shen X; Yuan Y; Zhang W; Yang C; Yao M
Molecules; 2021 Jun; 26(13):. PubMed ID: 34202548
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
