305 related articles for article (PubMed ID: 28923481)
1. ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157.
Feuerbach D; Schindler P; Barske C; Joller S; Beng-Louka E; Worringer KA; Kommineni S; Kaykas A; Ho DJ; Ye C; Welzenbach K; Elain G; Klein L; Brzak I; Mir AK; Farady CJ; Aichholz R; Popp S; George N; Neumann U
Neurosci Lett; 2017 Nov; 660():109-114. PubMed ID: 28923481
[TBL] [Abstract][Full Text] [Related]
2. An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
Schlepckow K; Kleinberger G; Fukumori A; Feederle R; Lichtenthaler SF; Steiner H; Haass C
EMBO Mol Med; 2017 Oct; 9(10):1356-1365. PubMed ID: 28855300
[TBL] [Abstract][Full Text] [Related]
3. TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P; Sevalle J; Deery MJ; Fraser G; Zhou Y; Ståhl S; Franssen EH; Dodd RB; Qamar S; Gomez Perez-Nievas B; Nicol LS; Eketjäll S; Revell J; Jones C; Billinton A; St George-Hyslop PH; Chessell I; Crowther DC
EMBO Mol Med; 2017 Oct; 9(10):1366-1378. PubMed ID: 28855301
[TBL] [Abstract][Full Text] [Related]
4. The Gut-Brain Axis in Autism Spectrum Disorder: A Focus on the Metalloproteases ADAM10 and ADAM17.
Zheng Y; Verhoeff TA; Perez Pardo P; Garssen J; Kraneveld AD
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33374371
[TBL] [Abstract][Full Text] [Related]
5. Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17.
Franke M; Schröder J; Monhasery N; Ackfeld T; Hummel TM; Rabe B; Garbers C; Becker-Pauly C; Floss DM; Scheller J
J Biol Chem; 2016 May; 291(20):10551-61. PubMed ID: 26961870
[TBL] [Abstract][Full Text] [Related]
6. Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).
Glebov K; Wunderlich P; Karaca I; Walter J
J Neuroinflammation; 2016 Jan; 13():17. PubMed ID: 26792193
[TBL] [Abstract][Full Text] [Related]
7. Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage.
Wunderlich P; Glebov K; Kemmerling N; Tien NT; Neumann H; Walter J
J Biol Chem; 2013 Nov; 288(46):33027-36. PubMed ID: 24078628
[TBL] [Abstract][Full Text] [Related]
8. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
Riethmueller S; Ehlers JC; Lokau J; Düsterhöft S; Knittler K; Dombrowsky G; Grötzinger J; Rabe B; Rose-John S; Garbers C
Sci Rep; 2016 May; 6():25550. PubMed ID: 27151651
[TBL] [Abstract][Full Text] [Related]
9. Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17.
Buchanan PC; Boylan KLM; Walcheck B; Heinze R; Geller MA; Argenta PA; Skubitz APN
J Biol Chem; 2017 Apr; 292(15):6339-6351. PubMed ID: 28232483
[TBL] [Abstract][Full Text] [Related]
10. Meprin β cleaves TREM2 and controls its phagocytic activity on macrophages.
Berner DK; Wessolowski L; Armbrust F; Schneppenheim J; Schlepckow K; Koudelka T; Scharfenberg F; Lucius R; Tholey A; Kleinberger G; Haass C; Arnold P; Becker-Pauly C
FASEB J; 2020 May; 34(5):6675-6687. PubMed ID: 32237095
[TBL] [Abstract][Full Text] [Related]
11. The collectrin-like part of the SARS-CoV-1 and -2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17.
Niehues RV; Wozniak J; Wiersch F; Lilienthal E; Tacken N; Schumertl T; Garbers C; Ludwig A; Düsterhöft S
FASEB J; 2022 Mar; 36(3):e22234. PubMed ID: 35199397
[TBL] [Abstract][Full Text] [Related]
12. Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Song WM; Joshita S; Zhou Y; Ulland TK; Gilfillan S; Colonna M
J Exp Med; 2018 Mar; 215(3):745-760. PubMed ID: 29321225
[TBL] [Abstract][Full Text] [Related]
13. Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.
Biswas S; Adrian M; Weber J; Evdokimov K; Winkler M; Géraud C
Biochem Biophys Res Commun; 2016 Sep; 477(4):661-666. PubMed ID: 27349870
[TBL] [Abstract][Full Text] [Related]
14. Degradome of soluble ADAM10 and ADAM17 metalloproteases.
Scharfenberg F; Helbig A; Sammel M; Benzel J; Schlomann U; Peters F; Wichert R; Bettendorff M; Schmidt-Arras D; Rose-John S; Moali C; Lichtenthaler SF; Pietrzik CU; Bartsch JW; Tholey A; Becker-Pauly C
Cell Mol Life Sci; 2020 Jan; 77(2):331-350. PubMed ID: 31209506
[TBL] [Abstract][Full Text] [Related]
15. Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine.
Schweigert O; Dewitz C; Möller-Hackbarth K; Trad A; Garbers C; Rose-John S; Scheller J
Biochim Biophys Acta; 2014 Feb; 1843(2):275-87. PubMed ID: 24286866
[TBL] [Abstract][Full Text] [Related]
16. Proteolytic Shedding of Human Colony-Stimulating Factor 1 Receptor and its implication.
Wei Y; Ma M; Lin S; Li X; Shu Y; Wang Z; Zhou Y; Hu B; Cheng B; Duan S; Huang X; Xu H; Zhang YW; Zheng H
J Cell Mol Med; 2021 May; 25(9):4516-4521. PubMed ID: 33783963
[TBL] [Abstract][Full Text] [Related]
17. TREM2 expression in the brain and biological fluids in prion diseases.
Diaz-Lucena D; Kruse N; Thüne K; Schmitz M; Villar-Piqué A; da Cunha JEG; Hermann P; López-Pérez Ó; Andrés-Benito P; Ladogana A; Calero M; Vidal E; Riggert J; Pineau H; Sim V; Zetterberg H; Blennow K; Del Río JA; Marín-Moreno A; Espinosa JC; Torres JM; Sánchez-Valle R; Mollenhauer B; Ferrer I; Zerr I; Llorens F
Acta Neuropathol; 2021 Jun; 141(6):841-859. PubMed ID: 33881612
[TBL] [Abstract][Full Text] [Related]
18. Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.
Groth E; Pruessmeyer J; Babendreyer A; Schumacher J; Pasqualon T; Dreymueller D; Higashiyama S; Lorenzen I; Grötzinger J; Cataldo D; Ludwig A
Biochim Biophys Acta; 2016 Nov; 1863(11):2795-2808. PubMed ID: 27599715
[TBL] [Abstract][Full Text] [Related]
19. Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.
Matthews AL; Noy PJ; Reyat JS; Tomlinson MG
Platelets; 2017 Jun; 28(4):333-341. PubMed ID: 27256961
[TBL] [Abstract][Full Text] [Related]
20. Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Atagi Y; Liu CC; Painter MM; Chen XF; Verbeeck C; Zheng H; Li X; Rademakers R; Kang SS; Xu H; Younkin S; Das P; Fryer JD; Bu G
J Biol Chem; 2015 Oct; 290(43):26043-50. PubMed ID: 26374899
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]