206 related articles for article (PubMed ID: 28925395)
1. Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization.
Ferrara M; Sessa G; Fiore M; Bernard F; Asteriti IA; Cundari E; Colotti G; Ferla S; Desideri M; Buglioni S; Trisciuoglio D; Del Bufalo D; Brancale A; Degrassi F
Oncogene; 2018 Jan; 37(2):231-240. PubMed ID: 28925395
[TBL] [Abstract][Full Text] [Related]
2. N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics.
Orticello M; Fiore M; Totta P; Desideri M; Barisic M; Passeri D; Lenzi J; Rosa A; Orlandi A; Maiato H; Del Bufalo D; Degrassi F
Oncogene; 2015 Jun; 34(25):3325-35. PubMed ID: 25132262
[TBL] [Abstract][Full Text] [Related]
3. Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule-kinetochore attachment.
Zhao G; Cheng Y; Gui P; Cui M; Liu W; Wang W; Wang X; Ali M; Dou Z; Niu L; Liu H; Anderson L; Ruan K; Hong J; Yao X
J Biol Chem; 2019 Jan; 294(2):576-592. PubMed ID: 30409912
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of Hec1 as a novel approach for treatment of primary liver cancer.
Huang LY; Chang CC; Lee YS; Huang JJ; Chuang SH; Chang JM; Kao KJ; Lau GM; Tsai PY; Liu CW; Lin HS; Gish RG; Lau JY
Cancer Chemother Pharmacol; 2014 Sep; 74(3):511-20. PubMed ID: 25038613
[TBL] [Abstract][Full Text] [Related]
5. Accurate phosphoregulation of kinetochore-microtubule affinity requires unconstrained molecular interactions.
Zaytsev AV; Sundin LJ; DeLuca KF; Grishchuk EL; DeLuca JG
J Cell Biol; 2014 Jul; 206(1):45-59. PubMed ID: 24982430
[TBL] [Abstract][Full Text] [Related]
6. Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1).
Miller SA; Johnson ML; Stukenberg PT
Curr Biol; 2008 Nov; 18(22):1785-91. PubMed ID: 19026542
[TBL] [Abstract][Full Text] [Related]
7. Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.
Lin YT; Chen Y; Wu G; Lee WH
Oncogene; 2006 Nov; 25(52):6901-14. PubMed ID: 16732327
[TBL] [Abstract][Full Text] [Related]
8. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1.
DeLuca JG; Gall WE; Ciferri C; Cimini D; Musacchio A; Salmon ED
Cell; 2006 Dec; 127(5):969-82. PubMed ID: 17129782
[TBL] [Abstract][Full Text] [Related]
9. A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds.
Screpanti E; Santaguida S; Nguyen T; Silvestri R; Gussio R; Musacchio A; Hamel E; De Wulf P
PLoS One; 2010 Jul; 5(7):e11603. PubMed ID: 20657644
[TBL] [Abstract][Full Text] [Related]
10. Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.
Guimaraes GJ; Dong Y; McEwen BF; Deluca JG
Curr Biol; 2008 Nov; 18(22):1778-84. PubMed ID: 19026543
[TBL] [Abstract][Full Text] [Related]
11. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal.
Wu G; Qiu XL; Zhou L; Zhu J; Chamberlin R; Lau J; Chen PL; Lee WH
Cancer Res; 2008 Oct; 68(20):8393-9. PubMed ID: 18922912
[TBL] [Abstract][Full Text] [Related]
12. Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism.
Hu CM; Zhu J; Guo XE; Chen W; Qiu XL; Ngo B; Chien R; Wang YV; Tsai CY; Wu G; Kim Y; Lopez R; Chamberlin AR; Lee EY; Lee WH
Oncogene; 2015 Mar; 34(10):1220-30. PubMed ID: 24662830
[TBL] [Abstract][Full Text] [Related]
13. Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation.
Pellacani C; Bucciarelli E; Renda F; Hayward D; Palena A; Chen J; Bonaccorsi S; Wakefield JG; Gatti M; Somma MP
Elife; 2018 Nov; 7():. PubMed ID: 30475206
[TBL] [Abstract][Full Text] [Related]
14. Hec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing Microtubules.
Long AF; Udy DB; Dumont S
Curr Biol; 2017 Jun; 27(11):1692-1699.e3. PubMed ID: 28552353
[TBL] [Abstract][Full Text] [Related]
15. RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.
Raaijmakers JA; Tanenbaum ME; Maia AF; Medema RH
J Cell Sci; 2009 Jul; 122(Pt 14):2436-45. PubMed ID: 19549680
[TBL] [Abstract][Full Text] [Related]
16. Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.
DeLuca JG; Dong Y; Hergert P; Strauss J; Hickey JM; Salmon ED; McEwen BF
Mol Biol Cell; 2005 Feb; 16(2):519-31. PubMed ID: 15548592
[TBL] [Abstract][Full Text] [Related]
17. Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression.
Ngo B; Hu CM; Guo XE; Ngo B; Wei R; Zhu J; Lee WH
J Biol Chem; 2013 Nov; 288(48):34403-13. PubMed ID: 24129578
[TBL] [Abstract][Full Text] [Related]
18. Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway.
Ferretti C; Totta P; Fiore M; Mattiuzzo M; Schillaci T; Ricordy R; Di Leonardo A; Degrassi F
Cell Cycle; 2010 Oct; 9(20):4174-82. PubMed ID: 20948316
[TBL] [Abstract][Full Text] [Related]
19. LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.
Qin M; Peng S; Liu N; Hu M; He Y; Li G; Chen H; He Y; Chen A; Wang X; Liu M; Chen Y; Yi Z
J Pharmacol Exp Ther; 2015 Dec; 355(3):473-83. PubMed ID: 26377911
[TBL] [Abstract][Full Text] [Related]
20. Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity.
Zaytsev AV; Mick JE; Maslennikov E; Nikashin B; DeLuca JG; Grishchuk EL
Mol Biol Cell; 2015 May; 26(10):1829-44. PubMed ID: 25808492
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]