BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28928138)

  • 1. Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation.
    Sharanek A; Burban A; Humbert L; Guguen-Guillouzo C; Rainteau D; Guillouzo A
    Drug Metab Dispos; 2017 Dec; 45(12):1292-1303. PubMed ID: 28928138
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential.
    Burban A; Sharanek A; Humbert L; Eguether T; Guguen-Guillouzo C; Rainteau D; Guillouzo A
    Toxicol Sci; 2019 Apr; 168(2):474-485. PubMed ID: 30629237
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes.
    Sharanek A; Burban A; Humbert L; Bachour-El Azzi P; Felix-Gomes N; Rainteau D; Guillouzo A
    Toxicol Sci; 2015 Oct; 147(2):573-87. PubMed ID: 26198044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.
    Notenboom S; Weigand KM; Proost JH; van Lipzig MMH; van de Steeg E; van den Broek PHH; Greupink R; Russel FGM; Groothuis GMM
    Eur J Pharm Sci; 2018 Mar; 115():175-184. PubMed ID: 29309877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury.
    Qiu X; Zhang Y; Liu T; Shen H; Xiao Y; Bourner MJ; Pratt JR; Thompson DC; Marathe P; Humphreys WG; Lai Y
    Mol Pharm; 2016 Apr; 13(4):1206-16. PubMed ID: 26910619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Troglitazone Inhibits Bile Acid Amidation: A Possible Risk Factor for Liver Injury.
    Ogimura E; Nakagawa T; Deguchi J; Sekine S; Ito K; Bando K
    Toxicol Sci; 2017 Aug; 158(2):347-355. PubMed ID: 28486596
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sulfation of bile salts: a new metabolic pathway.
    Stiehl A
    Digestion; 1974; 11(5-6):406-13. PubMed ID: 4618540
    [No Abstract]   [Full Text] [Related]  

  • 8. Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
    Anthérieu S; Bachour-El Azzi P; Dumont J; Abdel-Razzak Z; Guguen-Guillouzo C; Fromenty B; Robin MA; Guillouzo A
    Hepatology; 2013 Apr; 57(4):1518-29. PubMed ID: 23175273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.
    Bachour-El Azzi P; Sharanek A; Abdel-Razzak Z; Antherieu S; Al-Attrache H; Savary CC; Lepage S; Morel I; Labbe G; Guguen-Guillouzo C; Guillouzo A
    Drug Metab Dispos; 2014 Sep; 42(9):1556-66. PubMed ID: 25002748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Formation of bile acid sulfate esters in perfused rat livers following bile duct occlusion].
    Liersch M; Stiehl A
    Z Gastroenterol; 1974 Mar; 12(2):131-4. PubMed ID: 4825092
    [No Abstract]   [Full Text] [Related]  

  • 11. Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction.
    Perreault M; Białek A; Trottier J; Verreault M; Caron P; Milkiewicz P; Barbier O
    PLoS One; 2013; 8(11):e80994. PubMed ID: 24244729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes.
    Oizumi K; Sekine S; Fukagai M; Susukida T; Ito K
    J Pharm Sci; 2017 Sep; 106(9):2412-2419. PubMed ID: 28552691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis.
    Burbank MG; Burban A; Sharanek A; Weaver RJ; Guguen-Guillouzo C; Guillouzo A
    Drug Metab Dispos; 2016 Nov; 44(11):1780-1793. PubMed ID: 27538918
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.
    Májer F; Sharma R; Mullins C; Keogh L; Phipps S; Duggan S; Kelleher D; Keely S; Long A; Radics G; Wang J; Gilmer JF
    Bioorg Med Chem; 2014 Jan; 22(1):256-68. PubMed ID: 24332653
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
    Ghallab A; González D; Strängberg E; Hofmann U; Myllys M; Hassan R; Hobloss Z; Brackhagen L; Begher-Tibbe B; Duda JC; Drenda C; Kappenberg F; Reinders J; Friebel A; Vucur M; Turajski M; Seddek AL; Abbas T; Abdelmageed N; Morad SAF; Morad W; Hamdy A; Albrecht W; Kittana N; Assali M; Vartak N; van Thriel C; Sous A; Nell P; Villar-Fernandez M; Cadenas C; Genc E; Marchan R; Luedde T; Åkerblad P; Mattsson J; Marschall HU; Hoehme S; Stirnimann G; Schwab M; Boor P; Amann K; Schmitz J; Bräsen JH; Rahnenführer J; Edlund K; Karpen SJ; Simbrunner B; Reiberger T; Mandorfer M; Trauner M; Dawson PA; Lindström E; Hengstler JG
    J Hepatol; 2024 Feb; 80(2):268-281. PubMed ID: 37939855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rat precision-cut liver slices predict drug-induced cholestatic injury.
    Starokozhko V; Greupink R; van de Broek P; Soliman N; Ghimire S; de Graaf IAM; Groothuis GMM
    Arch Toxicol; 2017 Oct; 91(10):3403-3413. PubMed ID: 28391356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism.
    Hu X; Bonde Y; Eggertsen G; Rudling M
    J Intern Med; 2014 Jan; 275(1):27-38. PubMed ID: 24118394
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression.
    Vanwijngaerden YM; Wauters J; Langouche L; Vander Perre S; Liddle C; Coulter S; Vanderborght S; Roskams T; Wilmer A; Van den Berghe G; Mesotten D
    Hepatology; 2011 Nov; 54(5):1741-52. PubMed ID: 21800341
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The profile of bile acids and their sulfate metabolites in human urine and serum.
    Bathena SP; Mukherjee S; Olivera M; Alnouti Y
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Dec; 942-943():53-62. PubMed ID: 24212143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
    Chang JH; Sangaraju D; Liu N; Jaochico A; Plise E
    Mol Pharm; 2019 Oct; 16(10):4230-4240. PubMed ID: 31509422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.