275 related articles for article (PubMed ID: 28928732)
1. Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis.
Tiller KE; Chowdhury R; Li T; Ludwig SD; Sen S; Maranas CD; Tessier PM
Front Immunol; 2017; 8():986. PubMed ID: 28928732
[TBL] [Abstract][Full Text] [Related]
2. Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.
Tiller KE; Li L; Kumar S; Julian MC; Garde S; Tessier PM
J Biol Chem; 2017 Oct; 292(40):16638-16652. PubMed ID: 28778924
[TBL] [Abstract][Full Text] [Related]
3. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
Wu H; Nie Y; Huse WD; Watkins JD
J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035
[TBL] [Abstract][Full Text] [Related]
4. A general method for greatly improving the affinity of antibodies by using combinatorial libraries.
Rajpal A; Beyaz N; Haber L; Cappuccilli G; Yee H; Bhatt RR; Takeuchi T; Lerner RA; Crea R
Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8466-71. PubMed ID: 15939870
[TBL] [Abstract][Full Text] [Related]
5. Combinatorial mutagenesis with alternative CDR-L1 and -H2 loop lengths contributes to affinity maturation of antibodies.
Brockmann EC; Pyykkö M; Hannula H; Khan K; Lamminmäki U; Huovinen T
N Biotechnol; 2021 Jan; 60():173-182. PubMed ID: 33039698
[TBL] [Abstract][Full Text] [Related]
6. Design and construction of small perturbation mutagenesis libraries for antibody affinity maturation using massive microchip-synthesized oligonucleotides.
Xu M; Hu S; Ding B; Fei C; Wan W; Hu D; Du R; Zhou X; Hong J; Liu H; Gao X; Liu J
J Biotechnol; 2015 Jan; 194():27-36. PubMed ID: 25444869
[TBL] [Abstract][Full Text] [Related]
7. Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies.
Julian MC; Lee CC; Tiller KE; Rabia LA; Day EK; Schick AJ; Tessier PM
Protein Eng Des Sel; 2015 Oct; 28(10):339-50. PubMed ID: 26386257
[TBL] [Abstract][Full Text] [Related]
8. Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
Finlay WJ; Cunningham O; Lambert MA; Darmanin-Sheehan A; Liu X; Fennell BJ; Mahon CM; Cummins E; Wade JM; O'Sullivan CM; Tan XY; Piche N; Pittman DD; Paulsen J; Tchistiakova L; Kodangattil S; Gill D; Hufton SE
J Mol Biol; 2009 May; 388(3):541-58. PubMed ID: 19285987
[TBL] [Abstract][Full Text] [Related]
9. Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability.
Julian MC; Li L; Garde S; Wilen R; Tessier PM
Sci Rep; 2017 Mar; 7():45259. PubMed ID: 28349921
[TBL] [Abstract][Full Text] [Related]
10. Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain.
Almagro JC; Raghunathan G; Beil E; Janecki DJ; Chen Q; Dinh T; LaCombe A; Connor J; Ware M; Kim PH; Swanson RV; Fransson J
J Mol Recognit; 2012 Mar; 25(3):125-35. PubMed ID: 22407976
[TBL] [Abstract][Full Text] [Related]
11. Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries.
Azevedo Reis Teixeira A; Erasmus MF; D'Angelo S; Naranjo L; Ferrara F; Leal-Lopes C; Durrant O; Galmiche C; Morelli A; Scott-Tucker A; Bradbury ARM
MAbs; 2021; 13(1):1980942. PubMed ID: 34850665
[TBL] [Abstract][Full Text] [Related]
12. High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.
Lee CV; Liang WC; Dennis MS; Eigenbrot C; Sidhu SS; Fuh G
J Mol Biol; 2004 Jul; 340(5):1073-93. PubMed ID: 15236968
[TBL] [Abstract][Full Text] [Related]
13. Evolution of an interloop disulfide bond in high-affinity antibody mimics based on fibronectin type III domain and selected by yeast surface display: molecular convergence with single-domain camelid and shark antibodies.
Lipovsek D; Lippow SM; Hackel BJ; Gregson MW; Cheng P; Kapila A; Wittrup KD
J Mol Biol; 2007 May; 368(4):1024-41. PubMed ID: 17382960
[TBL] [Abstract][Full Text] [Related]
14. High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.
Fellouse FA; Esaki K; Birtalan S; Raptis D; Cancasci VJ; Koide A; Jhurani P; Vasser M; Wiesmann C; Kossiakoff AA; Koide S; Sidhu SS
J Mol Biol; 2007 Nov; 373(4):924-40. PubMed ID: 17825836
[TBL] [Abstract][Full Text] [Related]
15. Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity.
Sharma P; Kranz DM
J Biol Chem; 2018 Feb; 293(5):1820-1834. PubMed ID: 29229779
[TBL] [Abstract][Full Text] [Related]
16. Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies.
Hu D; Hu S; Wan W; Xu M; Du R; Zhao W; Gao X; Liu J; Liu H; Hong J
PLoS One; 2015; 10(6):e0129125. PubMed ID: 26046845
[TBL] [Abstract][Full Text] [Related]
17. Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions.
Sidhu SS; Li B; Chen Y; Fellouse FA; Eigenbrot C; Fuh G
J Mol Biol; 2004 Apr; 338(2):299-310. PubMed ID: 15066433
[TBL] [Abstract][Full Text] [Related]
18. Reduction of therapeutic antibody self-association using yeast-display selections and machine learning.
Makowski EK; Chen H; Lambert M; Bennett EM; Eschmann NS; Zhang Y; Zupancic JM; Desai AA; Smith MD; Lou W; Fernando A; Tully T; Gallo CJ; Lin L; Tessier PM
MAbs; 2022; 14(1):2146629. PubMed ID: 36433737
[TBL] [Abstract][Full Text] [Related]
19. In vitro antibody maturation. Improvement of a high affinity, neutralizing antibody against IL-1 beta.
Jackson JR; Sathe G; Rosenberg M; Sweet R
J Immunol; 1995 Apr; 154(7):3310-9. PubMed ID: 7897213
[TBL] [Abstract][Full Text] [Related]
20. Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human V
Henry KA; Kim DY; Kandalaft H; Lowden MJ; Yang Q; Schrag JD; Hussack G; MacKenzie CR; Tanha J
Front Immunol; 2017; 8():1759. PubMed ID: 29375542
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]