106 related articles for article (PubMed ID: 28933122)
1. [Hepatotoxicity of emodin based on UGT1A1 enzyme-mediated bilirubin in liver microsomes].
Wang Q; Dai Z; Zhang YJ; Ma SC
Zhongguo Zhong Yao Za Zhi; 2016 Dec; 41(23):4424-4427. PubMed ID: 28933122
[TBL] [Abstract][Full Text] [Related]
2. Simultaneous determination of bilirubin and its glucuronides in liver microsomes and recombinant UGT1A1 enzyme incubation systems by HPLC method and its application to bilirubin glucuronidation studies.
Ma G; Lin J; Cai W; Tan B; Xiang X; Zhang Y; Zhang P
J Pharm Biomed Anal; 2014 Apr; 92():149-59. PubMed ID: 24525562
[TBL] [Abstract][Full Text] [Related]
3. Estimating the Differences of UGT1A1 Activity in Recombinant UGT1A1 Enzyme, Human Liver Microsomes and Rat Liver Microsome Incubation Systems in Vitro.
Wang Q; Dai Z; Wen B; Ma S; Zhang Y
Biol Pharm Bull; 2015; 38(12):1910-7. PubMed ID: 26632182
[TBL] [Abstract][Full Text] [Related]
4. [Study on hepatotoxicity of physcion based on liver metabolism in vitro].
Wang Q; Wang YD; Yang JB; Liu Y; Wen HR; Ma SC
Zhongguo Zhong Yao Za Zhi; 2019 Jun; 44(11):2367-2372. PubMed ID: 31359665
[TBL] [Abstract][Full Text] [Related]
5. Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.
Wang Q; Wang Y; Li Y; Wen B; Dai Z; Ma S; Zhang Y
Sci Rep; 2017 Dec; 7(1):17952. PubMed ID: 29263357
[TBL] [Abstract][Full Text] [Related]
6. Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid.
Wang Q; Wen H; Ma S; Zhang Y
J Ethnopharmacol; 2022 Oct; 296():115461. PubMed ID: 35728710
[TBL] [Abstract][Full Text] [Related]
7. Insight into the practical models for prediciting the essential role of the cytochrome P450-mediated biotransformation in emodin-associated hepatotoxicity.
Zhang T; He X; Sun L; Wang D; Zhang S; Mao J; Zhang F
Toxicology; 2021 Oct; 462():152930. PubMed ID: 34492313
[TBL] [Abstract][Full Text] [Related]
8. Emodin-induced hepatotoxicity was exacerbated by probenecid through inhibiting UGTs and MRP2.
Wu L; Chen Y; Liu H; Zhan Z; Liang Z; Zhang T; Cai Z; Ye L; Liu M; Zhao J; Liu S; Tang L
Toxicol Appl Pharmacol; 2018 Nov; 359():91-101. PubMed ID: 30248416
[TBL] [Abstract][Full Text] [Related]
9. A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays.
Putluru SP; Matta MK; Ahire D; Subramanian M; Sinz M; Mandlekar S
Drug Metab Lett; 2017; 10(4):264-269. PubMed ID: 27908259
[TBL] [Abstract][Full Text] [Related]
10. [Study on potential hepatotoxicity of rhein in Rhei Radix et Rhizoma based on liver metabolism].
Wang Q; Wang YD; Yang JB; Liu Y; Wen HR; Ma SC
Zhongguo Zhong Yao Za Zhi; 2020 Jan; 45(2):412-417. PubMed ID: 32237326
[TBL] [Abstract][Full Text] [Related]
11. Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases.
Lv X; Wang XX; Hou J; Fang ZZ; Wu JJ; Cao YF; Liu SW; Ge GB; Yang L
Toxicol Appl Pharmacol; 2016 Jun; 301():42-9. PubMed ID: 27089846
[TBL] [Abstract][Full Text] [Related]
12. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes.
Tachibana M; Tanaka M; Masubuchi Y; Horie T
Drug Metab Dispos; 2005 Jun; 33(6):803-11. PubMed ID: 15769885
[TBL] [Abstract][Full Text] [Related]
13. [Inhibitory effect of different species of hydroxygenkwanin on UGTs and UGT1A1 activities].
Miao PP; Zhao YY; Miao Q; Guo CE; Chen HY; Chen N; Zhang YJ; Ma SC
Zhongguo Zhong Yao Za Zhi; 2016 Feb; 41(3):504-508. PubMed ID: 28868871
[TBL] [Abstract][Full Text] [Related]
14. UDP-glucuronosyltransferase (UGT) 1A1 mainly contributes to the glucuronidation of trovafloxacin.
Fujiwara R; Sumida K; Kutsuno Y; Sakamoto M; Itoh T
Drug Metab Pharmacokinet; 2015 Feb; 30(1):82-8. PubMed ID: 25760534
[TBL] [Abstract][Full Text] [Related]
15. Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi).
Wang XX; Lv X; Li SY; Hou J; Ning J; Wang JY; Cao YF; Ge GB; Guo B; Yang L
Toxicol Appl Pharmacol; 2015 Nov; 289(1):70-8. PubMed ID: 26348140
[TBL] [Abstract][Full Text] [Related]
16. [In vitro effects of Genkwa Flos chloroform extract on activity of human liver microsomes UGTs and UGT1A1].
Chen N; Miao PP; Guo CE; Chen HY; Ma PK; Li HP; Zhu HY; Gao X; Zhang YJ
Zhongguo Zhong Yao Za Zhi; 2016 Sep; 41(17):3296-3302. PubMed ID: 28920386
[TBL] [Abstract][Full Text] [Related]
17. Gender Differences in the Hepatotoxicity and Toxicokinetics of Emodin: The Potential Mechanisms Mediated by UGT2B7 and MRP2.
Wu L; Han W; Chen Y; Zhang T; Liu J; Zhong S; Liu H; Han C; Zhang Z; Liu S; Tang L
Mol Pharm; 2018 Sep; 15(9):3931-3945. PubMed ID: 30011215
[TBL] [Abstract][Full Text] [Related]
18. Warfarin is an effective modifier of multiple UDP-glucuronosyltransferase enzymes: evaluation of its potential to alter the pharmacokinetics of zidovudine.
Sun H; Zhang T; Wu Z; Wu B
J Pharm Sci; 2015 Jan; 104(1):244-56. PubMed ID: 25393417
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of rat liver UDP-glucuronosyltransferase by silymarin and the metabolite silibinin-glucuronide.
D'Andrea V; Pérez LM; Sánchez Pozzi EJ
Life Sci; 2005 Jun; 77(6):683-92. PubMed ID: 15921999
[TBL] [Abstract][Full Text] [Related]
20. Glucuronidation of antiallergic drug, Tranilast: identification of human UDP-glucuronosyltransferase isoforms and effect of its phase I metabolite.
Katoh M; Matsui T; Yokoi T
Drug Metab Dispos; 2007 Apr; 35(4):583-9. PubMed ID: 17220234
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
