These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells. Yoo BH; Wu X; Li Y; Haniff M; Sasazuki T; Shirasawa S; Eskelinen EL; Rosen KV J Biol Chem; 2010 Feb; 285(8):5438-49. PubMed ID: 19778902 [TBL] [Abstract][Full Text] [Related]
3. Increased ATG5-ATG12 in hepatitis B virus-associated hepatocellular carcinoma and their role in apoptosis. Kunanopparat A; Kimkong I; Palaga T; Tangkijvanich P; Sirichindakul B; Hirankarn N World J Gastroenterol; 2016 Oct; 22(37):8361-8374. PubMed ID: 27729742 [TBL] [Abstract][Full Text] [Related]
4. Foot-and-mouth disease virus infection suppresses autophagy and NF-кB antiviral responses via degradation of ATG5-ATG12 by 3C Fan X; Han S; Yan D; Gao Y; Wei Y; Liu X; Liao Y; Guo H; Sun S Cell Death Dis; 2017 Jan; 8(1):e2561. PubMed ID: 28102839 [TBL] [Abstract][Full Text] [Related]
5. Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells. Yoo BH; Wang Y; Erdogan M; Sasazuki T; Shirasawa S; Corcos L; Sabapathy K; Rosen KV J Biol Chem; 2011 Nov; 286(45):38894-903. PubMed ID: 21903589 [TBL] [Abstract][Full Text] [Related]
6. Autophagic activity dictates the cellular response to oncogenic RAS. Wang Y; Wang XD; Lapi E; Sullivan A; Jia W; He YW; Ratnayaka I; Zhong S; Goldin RD; Goemans CG; Tolkovsky AM; Lu X Proc Natl Acad Sci U S A; 2012 Aug; 109(33):13325-30. PubMed ID: 22847423 [TBL] [Abstract][Full Text] [Related]
7. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Lin TY; Chan HH; Chen SH; Sarvagalla S; Chen PS; Coumar MS; Cheng SM; Chang YC; Lin CH; Leung E; Cheung CHA Autophagy; 2020 Jul; 16(7):1296-1313. PubMed ID: 31612776 [TBL] [Abstract][Full Text] [Related]
8. miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate. Li SP; He JD; Wang Z; Yu Y; Fu SY; Zhang HM; Zhang JJ; Shen ZY World J Gastroenterol; 2016 May; 22(18):4501-14. PubMed ID: 27182160 [TBL] [Abstract][Full Text] [Related]
9. Dynamics of Atg5-Atg12-Atg16L1 Aggregation and Deaggregation. Kharaziha P; Panaretakis T Methods Enzymol; 2017; 587():247-255. PubMed ID: 28253959 [TBL] [Abstract][Full Text] [Related]
10. w09, a novel autophagy enhancer, induces autophagy-dependent cell apoptosis via activation of the EGFR-mediated RAS-RAF1-MAP2K-MAPK1/3 pathway. Zhang P; Zheng Z; Ling L; Yang X; Zhang N; Wang X; Hu M; Xia Y; Ma Y; Yang H; Wang Y; Liu H Autophagy; 2017 Jul; 13(7):1093-1112. PubMed ID: 28513279 [TBL] [Abstract][Full Text] [Related]
11. Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC. Won SJ; Yen CH; Lin TY; Jiang-Shieh YF; Lin CN; Chen JT; Su CL J Cell Physiol; 2018 Jan; 233(1):497-505. PubMed ID: 28294332 [TBL] [Abstract][Full Text] [Related]
12. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Goulielmaki M; Koustas E; Moysidou E; Vlassi M; Sasazuki T; Shirasawa S; Zografos G; Oikonomou E; Pintzas A Oncotarget; 2016 Feb; 7(8):9188-221. PubMed ID: 26802026 [TBL] [Abstract][Full Text] [Related]
13. SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12. González-Rodríguez P; Engskog-Vlachos P; Zhang H; Murgoci AN; Zerdes I; Joseph B Cell Death Dis; 2020 Jan; 11(1):69. PubMed ID: 31988284 [TBL] [Abstract][Full Text] [Related]
14. Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway. Kochetkova EY; Blinova GI; Bystrova OA; Martynova MG; Pospelov VA; Pospelova TV Aging (Albany NY); 2017 Nov; 9(11):2352-2375. PubMed ID: 29140794 [TBL] [Abstract][Full Text] [Related]
15. Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy. Alves S; Castro L; Fernandes MS; Francisco R; Castro P; Priault M; Chaves SR; Moyer MP; Oliveira C; Seruca R; Côrte-Real M; Sousa MJ; Preto A Oncotarget; 2015 Oct; 6(31):30787-802. PubMed ID: 26418750 [TBL] [Abstract][Full Text] [Related]
16. Identification and characterization of the autophagy-related genes Atg12 and Atg5 in hydra. Dixit NS; Shravage BV; Ghaskadbi S Int J Dev Biol; 2017; 61(6-7):389-395. PubMed ID: 28695958 [TBL] [Abstract][Full Text] [Related]
17. SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate. Wong CC; Qian Y; Li X; Xu J; Kang W; Tong JH; To KF; Jin Y; Li W; Chen H; Go MY; Wu JL; Cheng KW; Ng SS; Sung JJ; Cai Z; Yu J Gastroenterology; 2016 Nov; 151(5):945-960.e6. PubMed ID: 27451147 [TBL] [Abstract][Full Text] [Related]
18. Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation. Kim MJ; Woo SJ; Yoon CH; Lee JS; An S; Choi YH; Hwang SG; Yoon G; Lee SJ J Biol Chem; 2011 Apr; 286(15):12924-32. PubMed ID: 21300795 [TBL] [Abstract][Full Text] [Related]
19. Autophagy gene ATG5 knockdown upregulates apoptotic cell death during Candida albicans infection in human vaginal epithelial cells. Shroff A; Reddy KVR Am J Reprod Immunol; 2018 Dec; 80(6):e13056. PubMed ID: 30303264 [TBL] [Abstract][Full Text] [Related]