These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials. Desaphy JF; Carbonara R; Costanza T; Lentini G; Cavalluzzi MM; Bruno C; Franchini C; Camerino DC Mol Pharmacol; 2013 Feb; 83(2):406-15. PubMed ID: 23175529 [TBL] [Abstract][Full Text] [Related]
3. Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs. Desaphy JF; Carbonara R; Costanza T; Conte Camerino D Exp Neurol; 2014 May; 255(100):96-102. PubMed ID: 24613829 [TBL] [Abstract][Full Text] [Related]
4. Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole. Gualdani R; Cavalluzzi MM; Tadini-Buoninsegni F; Convertino M; Gailly P; Stary-Weinzinger A; Lentini G Cell Physiol Biochem; 2018; 45(6):2233-2245. PubMed ID: 29550817 [TBL] [Abstract][Full Text] [Related]
5. Differential effects of the neuroprotectant lubeluzole on bovine and mouse chromaffin cell calcium channel subtypes. Hernández-Guijo JM; Gandía L; de Pascual R; García AG Br J Pharmacol; 1997 Sep; 122(2):275-85. PubMed ID: 9313936 [TBL] [Abstract][Full Text] [Related]
6. Interaction of high concentrations of riluzole with recombinant skeletal muscle sodium channels and adult-type nicotinic receptor channels. Mohammadi B; Lang N; Dengler R; Bufler J Muscle Nerve; 2002 Oct; 26(4):539-45. PubMed ID: 12362421 [TBL] [Abstract][Full Text] [Related]
7. Site of action of lubeluzole on voltage-sensitive Ca(2+) channels in isolated dorsal root ganglion cells of the rat: influence of pH. Marrannes R; De Prins E J Pharmacol Exp Ther; 2000 Nov; 295(2):531-45. PubMed ID: 11046086 [TBL] [Abstract][Full Text] [Related]
8. Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. Song JH; Huang CS; Nagata K; Yeh JZ; Narahashi T J Pharmacol Exp Ther; 1997 Aug; 282(2):707-14. PubMed ID: 9262334 [TBL] [Abstract][Full Text] [Related]
9. Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells. Wang YJ; Lin MW; Lin AA; Wu SN Life Sci; 2008 Jan; 82(1-2):11-20. PubMed ID: 18068197 [TBL] [Abstract][Full Text] [Related]
10. Influence of lubeluzole on voltage-sensitive Ca++ channels in isolated rat neurons. Marrannes R; De Prins E; Clincke G J Pharmacol Exp Ther; 1998 Jul; 286(1):201-14. PubMed ID: 9655861 [TBL] [Abstract][Full Text] [Related]
11. Study of the interaction of lubeluzole with cardiac sodium channels. Le Grand B; Talmant JM; Rieu JP; Patoiseau JF; John GW J Cardiovasc Pharmacol; 2003 Nov; 42(5):581-7. PubMed ID: 14576504 [TBL] [Abstract][Full Text] [Related]
12. Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole. Hebert T; Drapeau P; Pradier L; Dunn RJ Mol Pharmacol; 1994 May; 45(5):1055-60. PubMed ID: 8190096 [TBL] [Abstract][Full Text] [Related]
13. Riluzole inhibits spontaneous Ca2+ signaling in neuroendocrine cells by activation of K+ channels and inhibition of Na+ channels. Beltran-Parrazal L; Charles A Br J Pharmacol; 2003 Nov; 140(5):881-8. PubMed ID: 14530220 [TBL] [Abstract][Full Text] [Related]
14. Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo. Desaphy JF; Farinato A; Altamura C; De Bellis M; Imbrici P; Tarantino N; Caccia C; Melloni E; Padoani G; Vailati S; Keywood C; Carratù MR; De Luca A; Conte D; Pierno S Exp Neurol; 2020 Jun; 328():113287. PubMed ID: 32205118 [TBL] [Abstract][Full Text] [Related]
15. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Coleman N; Nguyen HM; Cao Z; Brown BM; Jenkins DP; Zolkowska D; Chen YJ; Tanaka BS; Goldin AL; Rogawski MA; Pessah IN; Wulff H Neurotherapeutics; 2015 Jan; 12(1):234-49. PubMed ID: 25256961 [TBL] [Abstract][Full Text] [Related]
16. Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies. Stefani A; Spadoni F; Bernardi G Exp Neurol; 1997 Sep; 147(1):115-22. PubMed ID: 9294408 [TBL] [Abstract][Full Text] [Related]
17. Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block. Desaphy JF; De Luca A; Didonna MP; George AL; Camerino Conte D J Physiol; 2004 Jan; 554(Pt 2):321-34. PubMed ID: 14608015 [TBL] [Abstract][Full Text] [Related]