BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 28951129)

  • 1. Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway.
    Yoshikawa Y; Takano O; Kato I; Takahashi Y; Shima F; Kataoka T
    Cancer Lett; 2017 Dec; 410():82-91. PubMed ID: 28951129
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
    Pez F; Dayan F; Durivault J; Kaniewski B; Aimond G; Le Provost GS; Deux B; Clézardin P; Sommer P; Pouysségur J; Reynaud C
    Cancer Res; 2011 Mar; 71(5):1647-57. PubMed ID: 21239473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Huaier shows anti-cancer activities by inhibition of cell growth, migration and energy metabolism in lung cancer through PI3K/AKT/HIF-1α pathway.
    Liu X; Liu L; Chen K; Sun L; Li W; Zhang S
    J Cell Mol Med; 2021 Feb; 25(4):2228-2237. PubMed ID: 33377619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway.
    Wang H; Zhang C; Xu L; Zang K; Ning Z; Jiang F; Chi H; Zhu X; Meng Z
    Oncotarget; 2016 Apr; 7(15):20193-208. PubMed ID: 26958938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia inducible factor 1α-mediated LOX expression correlates with migration and invasion in epithelial ovarian cancer.
    Ji F; Wang Y; Qiu L; Li S; Zhu J; Liang Z; Wan Y; Di W
    Int J Oncol; 2013 May; 42(5):1578-88. PubMed ID: 23545606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.
    Jeay S; Pianetti S; Kagan HM; Sonenshein GE
    Mol Cell Biol; 2003 Apr; 23(7):2251-63. PubMed ID: 12640111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits.
    Wang L; Yin J; Wang X; Shao M; Duan F; Wu W; Peng P; Jin J; Tang Y; Ruan Y; Sun Y; Gu J
    Gastroenterology; 2016 May; 150(5):1183-1195.e16. PubMed ID: 26855187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport.
    Nagarajan A; Dogra SK; Sun L; Gandotra N; Ho T; Cai G; Cline G; Kumar P; Cowles RA; Wajapeyee N
    Mol Cell; 2017 Aug; 67(4):685-701.e6. PubMed ID: 28803777
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
    Nagaraju GP; Mezina A; Shaib WL; Landry J; El-Rayes BF
    Eur J Cancer; 2016 Jan; 52():109-19. PubMed ID: 26682870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer.
    Cheng CW; Chen PM; Hsieh YH; Weng CC; Chang CW; Yao CC; Hu LY; Wu PE; Shen CY
    Oncotarget; 2015 Dec; 6(42):44222-38. PubMed ID: 26528854
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 14-3-3ζ up-regulates hypoxia-inducible factor-1α in hepatocellular carcinoma via activation of PI3K/Akt/NF-кB signal transduction pathway.
    Tang Y; Lv P; Sun Z; Han L; Luo B; Zhou W
    Int J Clin Exp Pathol; 2015; 8(12):15845-53. PubMed ID: 26884855
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
    Tammali R; Saxena A; Srivastava SK; Ramana KV
    J Biol Chem; 2011 Jul; 286(27):24089-100. PubMed ID: 21576240
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.
    Baker AM; Cox TR; Bird D; Lang G; Murray GI; Sun XF; Southall SM; Wilson JR; Erler JT
    J Natl Cancer Inst; 2011 Mar; 103(5):407-24. PubMed ID: 21282564
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Requirement of hypoxia-inducible factor-1alpha down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab.
    Li X; Lu Y; Liang K; Pan T; Mendelsohn J; Fan Z
    Mol Cancer Ther; 2008 May; 7(5):1207-17. PubMed ID: 18483308
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stem cell factor/c-kit signaling enhances invasion of pancreatic cancer cells via HIF-1α under normoxic condition.
    Zhang M; Ma Q; Hu H; Zhang D; Li J; Ma G; Bhat K; Wu E
    Cancer Lett; 2011 Apr; 303(2):108-17. PubMed ID: 21320746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transforming growth factor alpha promotes osteosarcoma metastasis by ICAM-1 and PI3K/Akt signaling pathway.
    Hou CH; Lin FL; Tong KB; Hou SM; Liu JF
    Biochem Pharmacol; 2014 Jun; 89(4):453-63. PubMed ID: 24685520
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.
    Wu M; Min C; Wang X; Yu Z; Kirsch KH; Trackman PC; Sonenshein GE
    Cancer Res; 2007 Jul; 67(13):6278-85. PubMed ID: 17616686
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.