BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 28963139)

  • 1. PI3Kγ Activates Integrin α
    Foubert P; Kaneda MM; Varner JA
    Cancer Immunol Res; 2017 Nov; 5(11):957-968. PubMed ID: 28963139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
    Schmid MC; Franco I; Kang SW; Hirsch E; Quilliam LA; Varner JA
    PLoS One; 2013; 8(4):e60226. PubMed ID: 23565202
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
    Kaneda MM; Cappello P; Nguyen AV; Ralainirina N; Hardamon CR; Foubert P; Schmid MC; Sun P; Mose E; Bouvet M; Lowy AM; Valasek MA; Sasik R; Novelli F; Hirsch E; Varner JA
    Cancer Discov; 2016 Aug; 6(8):870-85. PubMed ID: 27179037
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PI3Kγ is a molecular switch that controls immune suppression.
    Kaneda MM; Messer KS; Ralainirina N; Li H; Leem CJ; Gorjestani S; Woo G; Nguyen AV; Figueiredo CC; Foubert P; Schmid MC; Pink M; Winkler DG; Rausch M; Palombella VJ; Kutok J; McGovern K; Frazer KA; Wu X; Karin M; Sasik R; Cohen EE; Varner JA
    Nature; 2016 Nov; 539(7629):437-442. PubMed ID: 27642729
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity.
    Wiehagen KR; Girgis NM; Yamada DH; Smith AA; Chan SR; Grewal IS; Quigley M; Verona RI
    Cancer Immunol Res; 2017 Dec; 5(12):1109-1121. PubMed ID: 29097420
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.
    Cresswell GM; Wang B; Kischuk EM; Broman MM; Alfar RA; Vickman RE; Dimitrov DS; Kularatne SA; Sundaram CP; Singhal S; Eruslanov EB; Crist SA; Elzey BD; Ratliff TL; Low PS
    Cancer Res; 2021 Feb; 81(3):671-684. PubMed ID: 33203700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells.
    Alissafi T; Hatzioannou A; Mintzas K; Barouni RM; Banos A; Sormendi S; Polyzos A; Xilouri M; Wielockx B; Gogas H; Verginis P
    J Clin Invest; 2018 Aug; 128(9):3840-3852. PubMed ID: 29920188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myeloid-derived suppressor cell function is reduced by Withaferin A, a potent and abundant component of Withania somnifera root extract.
    Sinha P; Ostrand-Rosenberg S
    Cancer Immunol Immunother; 2013 Nov; 62(11):1663-73. PubMed ID: 23982485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.
    Hossain F; Al-Khami AA; Wyczechowska D; Hernandez C; Zheng L; Reiss K; Valle LD; Trillo-Tinoco J; Maj T; Zou W; Rodriguez PC; Ochoa AC
    Cancer Immunol Res; 2015 Nov; 3(11):1236-47. PubMed ID: 26025381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Skewing the Th cell phenotype toward Th1 alters the maturation of tumor-infiltrating mononuclear phagocytes.
    Nonaka K; Saio M; Suwa T; Frey AB; Umemura N; Imai H; Ouyang GF; Osada S; Balazs M; Adany R; Kawaguchi Y; Yoshida K; Takami T
    J Leukoc Biol; 2008 Sep; 84(3):679-88. PubMed ID: 18566103
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.
    Schmid MC; Kang SW; Chen H; Paradise M; Ghebremedhin A; Kaneda MM; Chin SM; Do A; Watterson DM; Varner JA
    Nat Commun; 2022 Apr; 13(1):1768. PubMed ID: 35365657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor Microenvironment.
    Parker KH; Beury DW; Ostrand-Rosenberg S
    Adv Cancer Res; 2015; 128():95-139. PubMed ID: 26216631
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8+ T-cell activation events.
    Schouppe E; Mommer C; Movahedi K; Laoui D; Morias Y; Gysemans C; Luyckx A; De Baetselier P; Van Ginderachter JA
    Eur J Immunol; 2013 Nov; 43(11):2930-42. PubMed ID: 23878002
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer.
    Yu J; Du W; Yan F; Wang Y; Li H; Cao S; Yu W; Shen C; Liu J; Ren X
    J Immunol; 2013 Apr; 190(7):3783-97. PubMed ID: 23440412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transmembrane TNF-α promotes suppressive activities of myeloid-derived suppressor cells via TNFR2.
    Hu X; Li B; Li X; Zhao X; Wan L; Lin G; Yu M; Wang J; Jiang X; Feng W; Qin Z; Yin B; Li Z
    J Immunol; 2014 Feb; 192(3):1320-31. PubMed ID: 24379122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.
    Schlecker E; Stojanovic A; Eisen C; Quack C; Falk CS; Umansky V; Cerwenka A
    J Immunol; 2012 Dec; 189(12):5602-11. PubMed ID: 23152559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth.
    Schmid MC; Avraamides CJ; Foubert P; Shaked Y; Kang SW; Kerbel RS; Varner JA
    Cancer Res; 2011 Nov; 71(22):6965-75. PubMed ID: 21948958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth.
    Achyut BR; Angara K; Jain M; Borin TF; Rashid MH; Iskander ASM; Ara R; Kolhe R; Howard S; Venugopal N; Rodriguez PC; Bradford JW; Arbab AS
    Sci Rep; 2017 Oct; 7(1):13754. PubMed ID: 29062041
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.
    Zhou J; Qu Z; Sun F; Han L; Li L; Yan S; Stabile LP; Chen LF; Siegfried JM; Xiao G
    Cancer Immunol Res; 2017 Mar; 5(3):257-268. PubMed ID: 28108629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.
    De Henau O; Rausch M; Winkler D; Campesato LF; Liu C; Cymerman DH; Budhu S; Ghosh A; Pink M; Tchaicha J; Douglas M; Tibbitts T; Sharma S; Proctor J; Kosmider N; White K; Stern H; Soglia J; Adams J; Palombella VJ; McGovern K; Kutok JL; Wolchok JD; Merghoub T
    Nature; 2016 Nov; 539(7629):443-447. PubMed ID: 27828943
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.