These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 28965853)

  • 1. Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.
    Oladapo HO; Tarpley M; Sauer SJ; Addo KA; Ingram SM; Strepay D; Ehe BK; Chdid L; Trinkler M; Roques JR; Darr DB; Fleming JM; Devi GR; Williams KP
    Cancer Lett; 2017 Dec; 411():136-149. PubMed ID: 28965853
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
    Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
    Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
    Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.
    Thomas ZI; Gibson W; Sexton JZ; Aird KM; Ingram SM; Aldrich A; Lyerly HK; Devi GR; Williams KP
    Br J Cancer; 2011 May; 104(10):1575-86. PubMed ID: 21505458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
    Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
    J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells.
    Salem I; Alsalahi M; Chervoneva I; Aburto LD; Addya S; Ott GR; Ruggeri BA; Cristofanilli M; Fernandez SV
    Breast Cancer Res; 2016 Mar; 18(1):37. PubMed ID: 27009091
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells.
    Long B; Wang LX; Zheng FM; Lai SP; Xu DR; Hu Y; Lin DJ; Zhang XZ; Dong L; Long ZJ; Tong XZ; Liu Q
    Cell Physiol Biochem; 2016; 38(4):1288-302. PubMed ID: 27008269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin inhibits the invasion and metastasis of triple negative breast cancer via Hedgehog/Gli1 signaling pathway.
    Li M; Guo T; Lin J; Huang X; Ke Q; Wu Y; Fang C; Hu C
    J Ethnopharmacol; 2022 Jan; 283():114689. PubMed ID: 34592340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer.
    Riaz SK; Khan JS; Shah STA; Wang F; Ye L; Jiang WG; Malik MFA
    Cell Commun Signal; 2018 Jan; 16(1):3. PubMed ID: 29329585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone Deacetylase Inhibitor Enhances the Efficacy of MEK Inhibitor through NOXA-Mediated MCL1 Degradation in Triple-Negative and Inflammatory Breast Cancer.
    Torres-Adorno AM; Lee J; Kogawa T; Ordentlich P; Tripathy D; Lim B; Ueno NT
    Clin Cancer Res; 2017 Aug; 23(16):4780-4792. PubMed ID: 28465444
    [No Abstract]   [Full Text] [Related]  

  • 14. GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells.
    Bacelar Sacramento de Araújo T; de Oliveira Siquara da Rocha L; Torres Andion Vidal M; Cerqueira Coelho PL; Galvão Dos Reis M; Solano de Freitas Souza B; Botelho Pereira Soares M; Almeida Pereira T; Della Coletta R; Pereira Bezerra D; Borges Dias R; Araújo Gurgel Rocha C
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.
    Fu J; Rodova M; Roy SK; Sharma J; Singh KP; Srivastava RK; Shankar S
    Cancer Lett; 2013 Mar; 330(1):22-32. PubMed ID: 23200667
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.
    Colavito SA; Zou MR; Yan Q; Nguyen DX; Stern DF
    Breast Cancer Res; 2014 Sep; 16(5):444. PubMed ID: 25252859
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells.
    Abu Rabe D; Chdid L; Lamson DR; Laudeman CP; Tarpley M; Elsayed N; Smith GR; Zheng W; Dixon MS; Williams KP
    Molecules; 2024 Jun; 29(13):. PubMed ID: 38999049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death.
    Wang X; Wei S; Zhao Y; Shi C; Liu P; Zhang C; Lei Y; Zhang B; Bai B; Huang Y; Zhang H
    Cancer Lett; 2017 Jan; 385():128-136. PubMed ID: 27810405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling.
    Harada K; Ohashi R; Naito K; Kanki K
    Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32354204
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells.
    Mani C; Tripathi K; Omy TR; Reedy M; Manne U; Palle K
    Biochim Biophys Acta Mol Basis Dis; 2022 Feb; 1868(2):166300. PubMed ID: 34748904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.