BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 28970077)

  • 1. FBXO32 activates NF-κB through IκBα degradation in inflammatory and genotoxic stress.
    Meshram SN; Paul D; Manne R; Choppara S; Sankaran G; Agrawal Y; Santra MK
    Int J Biochem Cell Biol; 2017 Nov; 92():134-140. PubMed ID: 28970077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
    Spagnol V; Oliveira CAB; Randle SJ; Passos PMS; Correia CRSTB; Simaroli NB; Oliveira JS; Mevissen TET; Medeiros AC; Gomes MD; Komander D; Laman H; Teixeira FR
    Biochim Biophys Acta Gen Subj; 2021 Jan; 1865(1):129754. PubMed ID: 33010352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRF3 enhances NF-κB activation by targeting IκBα for degradation in teleost fish.
    Zhao X; Yan X; Huo R; Xu T
    Dev Comp Immunol; 2020 May; 106():103632. PubMed ID: 31987876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation.
    Zhou H; Liu Y; Zhu R; Ding F; Wan Y; Li Y; Liu Z
    Oncogene; 2017 Jun; 36(23):3312-3321. PubMed ID: 28068319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bmi1 Regulates IκBα Degradation via Association with the SCF Complex.
    Okuyama Y; Tanaka Y; Jiang JJ; Kamimura D; Nakamura A; Ota M; Ohki T; Higo D; Ogura H; Ishii N; Atsumi T; Murakami M
    J Immunol; 2018 Oct; 201(8):2264-2272. PubMed ID: 30209188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα.
    Schweitzer K; Pralow A; Naumann M
    J Cell Mol Med; 2016 Jan; 20(1):58-70. PubMed ID: 26463447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ORF2 glycoprotein of hepatitis E virus inhibits cellular NF-κB activity by blocking ubiquitination mediated proteasomal degradation of IκBα in human hepatoma cells.
    Surjit M; Varshney B; Lal SK
    BMC Biochem; 2012 May; 13():7. PubMed ID: 22590978
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity.
    Mei Z; Zhang D; Hu B; Wang J; Shen X; Xiao W
    J Biol Chem; 2015 Jun; 290(26):16202-14. PubMed ID: 25944903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha.
    Heissmeyer V; Krappmann D; Hatada EN; Scheidereit C
    Mol Cell Biol; 2001 Feb; 21(4):1024-35. PubMed ID: 11158290
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation of a proteolytic signal: E3/E2-mediated polyubiquitination of IκBα.
    Chong RA; Wu K; Kovacev J; Pan ZQ
    Methods Mol Biol; 2015; 1280():339-54. PubMed ID: 25736759
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro SCFbeta-Trcp1-mediated IkappaBalpha ubiquitination assay for high-throughput screen.
    Xu S; Patel P; Abbasian M; Giegel D; Xie W; Mercurio F; Cox S
    Methods Enzymol; 2005; 399():729-40. PubMed ID: 16338392
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hint1 Up-Regulates IκBα by Targeting the β-TrCP Subunit of SCF E3 Ligase in Human Hepatocellular Carcinoma Cells.
    Shi Z; Wu X; Ke Y; Wang L
    Dig Dis Sci; 2016 Mar; 61(3):785-94. PubMed ID: 26520111
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Control of IkappaBalpha proteolysis by the ubiquitin-proteasome pathway.
    Tanaka K; Kawakami T; Tateishi K; Yashiroda H; Chiba T
    Biochimie; 2001; 83(3-4):351-6. PubMed ID: 11295496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Liao X; Li Z; Zheng H; Qian W; Zhang S; Chen S; Li X; Tang M; Xu Y; Yu R; Li M; Song L; Li J
    Mol Cancer Res; 2023 Jul; 21(7):648-663. PubMed ID: 36961398
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100.
    Zhang Z; Wang Y; Li C; Shi Z; Hao Q; Wang W; Song X; Zhao Y; Jiao S; Zhou Z
    J Biol Chem; 2015 Aug; 290(32):19558-68. PubMed ID: 26112410
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The SCF
    Choppara S; Ganga S; Manne R; Dutta P; Singh S; Santra MK
    J Biol Chem; 2018 Oct; 293(42):16291-16306. PubMed ID: 30171069
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells.
    Rahimova N; Babazada H; Higuchi Y; Yamashita F; Hashida M
    Biochim Biophys Acta Mol Cell Res; 2019 Feb; 1866(2):190-198. PubMed ID: 30391277
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells.
    Shumway SD; Miyamoto S
    Biochem J; 2004 May; 380(Pt 1):173-80. PubMed ID: 14763901
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SM22α inhibits vascular inflammation via stabilization of IκBα in vascular smooth muscle cells.
    Shu YN; Zhang F; Bi W; Dong LH; Zhang DD; Chen R; Lv P; Xie XL; Lin YL; Xue ZY; Li H; Miao SB; Zhao LL; Wang H; Han M
    J Mol Cell Cardiol; 2015 Jul; 84():191-9. PubMed ID: 25937534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB.
    Usui S; Maejima Y; Pain J; Hong C; Cho J; Park JY; Zablocki D; Tian B; Glass DJ; Sadoshima J
    Circ Res; 2011 Jul; 109(2):161-71. PubMed ID: 21617130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.