BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 28971800)

  • 1. An unfolded protein-induced conformational switch activates mammalian IRE1.
    Karagöz GE; Acosta-Alvear D; Nguyen HT; Lee CP; Chu F; Walter P
    Elife; 2017 Oct; 6():. PubMed ID: 28971800
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers.
    Belyy V; Zuazo-Gaztelu I; Alamban A; Ashkenazi A; Walter P
    Elife; 2022 Jun; 11():. PubMed ID: 35730415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1.
    van Anken E; Pincus D; Coyle S; Aragón T; Osman C; Lari F; Gómez Puerta S; Korennykh AV; Walter P
    Elife; 2014 Dec; 3():e05031. PubMed ID: 25549299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.
    Li H; Korennykh AV; Behrman SL; Walter P
    Proc Natl Acad Sci U S A; 2010 Sep; 107(37):16113-8. PubMed ID: 20798350
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR.
    Amin-Wetzel N; Neidhardt L; Yan Y; Mayer MP; Ron D
    Elife; 2019 Dec; 8():. PubMed ID: 31873072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response.
    Gardner BM; Walter P
    Science; 2011 Sep; 333(6051):1891-4. PubMed ID: 21852455
    [TBL] [Abstract][Full Text] [Related]  

  • 7. On the mechanism of sensing unfolded protein in the endoplasmic reticulum.
    Credle JJ; Finer-Moore JS; Papa FR; Stroud RM; Walter P
    Proc Natl Acad Sci U S A; 2005 Dec; 102(52):18773-84. PubMed ID: 16365312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.
    Amin-Wetzel N; Saunders RA; Kamphuis MJ; Rato C; Preissler S; Harding HP; Ron D
    Cell; 2017 Dec; 171(7):1625-1637.e13. PubMed ID: 29198525
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins.
    Oikawa D; Kimata Y
    Methods Enzymol; 2011; 490():195-216. PubMed ID: 21266252
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Principles of IRE1 modulation using chemical tools.
    Lee KP; Sicheri F
    Methods Enzymol; 2011; 490():271-94. PubMed ID: 21266256
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
    Zhou J; Liu CY; Back SH; Clark RL; Peisach D; Xu Z; Kaufman RJ
    Proc Natl Acad Sci U S A; 2006 Sep; 103(39):14343-8. PubMed ID: 16973740
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Insights into IRE1 Functions in the Unfolded Protein Response.
    Yang J; Liu H; Li L; Liu H; Shi W; Yuan X; Wu L
    Curr Med Chem; 2016; 23(41):4706-4716. PubMed ID: 27686654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1.
    Korennykh AV; Egea PF; Korostelev AA; Finer-Moore J; Stroud RM; Zhang C; Shokat KM; Walter P
    BMC Biol; 2011 Jul; 9():48. PubMed ID: 21729334
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
    Ferri E; Le Thomas A; Wallweber HA; Day ES; Walters BT; Kaufman SE; Braun MG; Clark KR; Beresini MH; Mortara K; Chen YA; Canter B; Phung W; Liu PS; Lammens A; Ashkenazi A; Rudolph J; Wang W
    Nat Commun; 2020 Dec; 11(1):6387. PubMed ID: 33318494
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
    Acosta-Alvear D; Karagöz GE; Fröhlich F; Li H; Walther TC; Walter P
    Elife; 2018 Dec; 7():. PubMed ID: 30582518
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis of the unfolded protein response.
    Korennykh A; Walter P
    Annu Rev Cell Dev Biol; 2012; 28():251-77. PubMed ID: 23057742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.
    Oikawa D; Kimata Y; Kohno K; Iwawaki T
    Exp Cell Res; 2009 Sep; 315(15):2496-504. PubMed ID: 19538957
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IRE1: ER stress sensor and cell fate executor.
    Chen Y; Brandizzi F
    Trends Cell Biol; 2013 Nov; 23(11):547-55. PubMed ID: 23880584
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress.
    Kopp MC; Nowak PR; Larburu N; Adams CJ; Ali MM
    Elife; 2018 Jan; 7():. PubMed ID: 29303481
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative microscopy reveals dynamics and fate of clustered IRE1α.
    Belyy V; Tran NH; Walter P
    Proc Natl Acad Sci U S A; 2020 Jan; 117(3):1533-1542. PubMed ID: 31871156
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.