305 related articles for article (PubMed ID: 28971909)
1. Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.
Zhu X; Hu T; Ho MH; Wang Y; Yu M; Patel N; Pi W; Choi JH; Xu H; Ganapathy V; Kutlar F; Kutlar A; Tuan D
Haematologica; 2017 Dec; 102(12):1995-2004. PubMed ID: 28971909
[TBL] [Abstract][Full Text] [Related]
2. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.
Zhang Y; Paikari A; Sumazin P; Ginter Summarell CC; Crosby JR; Boerwinkle E; Weiss MJ; Sheehan VA
Blood; 2018 Jul; 132(3):321-333. PubMed ID: 29884740
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
Chou YC; Chen RL; Lai ZS; Song JS; Chao YS; Shen CK
Mol Cell Biol; 2015 Jul; 35(14):2541-53. PubMed ID: 25986606
[TBL] [Abstract][Full Text] [Related]
4. Quantification of HBG mRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia.
Pecoraro A; Rigano P; Troia A; Calzolari R; Scazzone C; Maggio A; Steinberg MH; Di Marzo R
Eur J Haematol; 2014 Jan; 92(1):66-72. PubMed ID: 24112139
[TBL] [Abstract][Full Text] [Related]
5. A systematic review of known mechanisms of hydroxyurea-induced fetal hemoglobin for treatment of sickle cell disease.
Pule GD; Mowla S; Novitzky N; Wiysonge CS; Wonkam A
Expert Rev Hematol; 2015 Oct; 8(5):669-79. PubMed ID: 26327494
[TBL] [Abstract][Full Text] [Related]
6. Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1.
Grieco AJ; Billett HH; Green NS; Driscoll MC; Bouhassira EE
PLoS One; 2015; 10(6):e0129431. PubMed ID: 26053062
[TBL] [Abstract][Full Text] [Related]
7. Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea.
Chondrou V; Stavrou EF; Markopoulos G; Kouraklis-Symeonidis A; Fotopoulos V; Symeonidis A; Vlachaki E; Chalkia P; Patrinos GP; Papachatzopoulou A; Sgourou A
Hum Genomics; 2018 Oct; 12(1):45. PubMed ID: 30285874
[TBL] [Abstract][Full Text] [Related]
8. Hydroxyurea down-regulates BCL11A, KLF-1 and MYB through miRNA-mediated actions to induce γ-globin expression: implications for new therapeutic approaches of sickle cell disease.
Pule GD; Mowla S; Novitzky N; Wonkam A
Clin Transl Med; 2016 Mar; 5(1):15. PubMed ID: 27056246
[TBL] [Abstract][Full Text] [Related]
9. Role of microRNA in hydroxyurea mediated HbF induction in sickle cell anaemia patients.
Kargutkar N; Sawant-Mulay M; Hariharan P; Chandrakala S; Nadkarni A
Sci Rep; 2023 Jan; 13(1):369. PubMed ID: 36611033
[TBL] [Abstract][Full Text] [Related]
10. Concordant fetal hemoglobin response to hydroxyurea in siblings with sickle cell disease.
Steinberg MH; Voskaridou E; Kutlar A; Loukopoulos D; Koshy M; Ballas SK; Castro O; Barton F
Am J Hematol; 2003 Feb; 72(2):121-6. PubMed ID: 12555216
[TBL] [Abstract][Full Text] [Related]
11. Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea.
Allard P; Alhaj N; Lobitz S; Cario H; Jarisch A; Grosse R; Oevermann L; Hakimeh D; Tagliaferri L; Kohne E; Kopp-Schneider A; Kulozik AE; Kunz JB
Haematologica; 2022 Jul; 107(7):1577-1588. PubMed ID: 34706496
[TBL] [Abstract][Full Text] [Related]
12. Determinants of fetal hemoglobin response to hydroxyurea.
Steinberg MH
Semin Hematol; 1997 Jul; 34(3 Suppl 3):8-14. PubMed ID: 9317196
[TBL] [Abstract][Full Text] [Related]
13. Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.
Rivers A; Vaitkus K; Jagadeeswaran R; Ruiz MA; Ibanez V; Ciceri F; Cavalcanti F; Molokie RE; Saunthararajah Y; Engel JD; DeSimone J; Lavelle D
Exp Hematol; 2018 Nov; 67():60-64.e2. PubMed ID: 30125603
[TBL] [Abstract][Full Text] [Related]
14. Reticulocyte parameters and hemoglobin F production in sickle cell disease patients undergoing hydroxyurea therapy.
Borba R; Lima CS; Grotto HZ
J Clin Lab Anal; 2003; 17(2):66-72. PubMed ID: 12640630
[TBL] [Abstract][Full Text] [Related]
15. The role of BCL11A and HMIP-2 polymorphisms on endogenous and hydroxyurea induced levels of fetal hemoglobin in sickle cell anemia patients from southern Brazil.
Friedrisch JR; Sheehan V; Flanagan JM; Baldan A; Summarell CC; Bittar CM; Friedrisch BK; Wilke II; Ribeiro CB; Daudt LE; da Rocha Silla LM
Blood Cells Mol Dis; 2016 Nov; 62():32-37. PubMed ID: 27838552
[TBL] [Abstract][Full Text] [Related]
16. Hydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression.
Zhu J; Chin K; Aerbajinai W; Kumkhaek C; Li H; Rodgers GP
Blood; 2014 Aug; 124(7):1146-56. PubMed ID: 24914133
[TBL] [Abstract][Full Text] [Related]
17. Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling.
De Souza DC; Hebert N; Esrick EB; Ciuculescu MF; Archer NM; Armant M; Audureau É; Brendel C; Di Caprio G; Galactéros F; Liu D; McCabe A; Morris E; Schonbrun E; Williams D; Wood DK; Williams DA; Bartolucci P; Higgins JM
Nat Commun; 2023 Sep; 14(1):5850. PubMed ID: 37730674
[TBL] [Abstract][Full Text] [Related]
18. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.
Wilber A; Tschulena U; Hargrove PW; Kim YS; Persons DA; Barbas CF; Nienhuis AW
Blood; 2010 Apr; 115(15):3033-41. PubMed ID: 20190190
[TBL] [Abstract][Full Text] [Related]
19. SIRT1 activates the expression of fetal hemoglobin genes.
Dai Y; Chen T; Ijaz H; Cho EH; Steinberg MH
Am J Hematol; 2017 Nov; 92(11):1177-1186. PubMed ID: 28776729
[TBL] [Abstract][Full Text] [Related]
20. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]