312 related articles for article (PubMed ID: 2897240)
1. An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene.
Choi KH; Chen CJ; Kriegler M; Roninson IB
Cell; 1988 May; 53(4):519-29. PubMed ID: 2897240
[TBL] [Abstract][Full Text] [Related]
2. Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.
Safa AR; Stern RK; Choi K; Agresti M; Tamai I; Mehta ND; Roninson IB
Proc Natl Acad Sci U S A; 1990 Sep; 87(18):7225-9. PubMed ID: 1976255
[TBL] [Abstract][Full Text] [Related]
3. Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.
Ueda K; Cardarelli C; Gottesman MM; Pastan I
Proc Natl Acad Sci U S A; 1987 May; 84(9):3004-8. PubMed ID: 3472246
[TBL] [Abstract][Full Text] [Related]
4. P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.
Kioka N; Tsubota J; Kakehi Y; Komano T; Gottesman MM; Pastan I; Ueda K
Biochem Biophys Res Commun; 1989 Jul; 162(1):224-31. PubMed ID: 2568832
[TBL] [Abstract][Full Text] [Related]
5. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.
Ueda K; Cornwell MM; Gottesman MM; Pastan I; Roninson IB; Ling V; Riordan JR
Biochem Biophys Res Commun; 1986 Dec; 141(3):956-62. PubMed ID: 2880583
[TBL] [Abstract][Full Text] [Related]
6. Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance.
Azzaria M; Schurr E; Gros P
Mol Cell Biol; 1989 Dec; 9(12):5289-97. PubMed ID: 2573836
[TBL] [Abstract][Full Text] [Related]
7. Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein.
Loo TW; Clarke DM
J Biol Chem; 1993 Feb; 268(5):3143-9. PubMed ID: 8094081
[TBL] [Abstract][Full Text] [Related]
8. A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps.
Gros P; Dhir R; Croop J; Talbot F
Proc Natl Acad Sci U S A; 1991 Aug; 88(16):7289-93. PubMed ID: 1678520
[TBL] [Abstract][Full Text] [Related]
9. Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA.
Lincke CR; van der Bliek AM; Schuurhuis GJ; van der Velde-Koerts T; Smit JJ; Borst P
Cancer Res; 1990 Mar; 50(6):1779-85. PubMed ID: 1968359
[TBL] [Abstract][Full Text] [Related]
10. Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification.
Shen DW; Fojo A; Chin JE; Roninson IB; Richert N; Pastan I; Gottesman MM
Science; 1986 May; 232(4750):643-5. PubMed ID: 3457471
[TBL] [Abstract][Full Text] [Related]
11. The direct activation of human multidrug resistance gene (MDR1) by anticancer agents.
Kohno K; Sato S; Takano H; Matsuo K; Kuwano M
Biochem Biophys Res Commun; 1989 Dec; 165(3):1415-21. PubMed ID: 2575381
[TBL] [Abstract][Full Text] [Related]
12. Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi.
Fairchild CR; Moscow JA; O'Brien EE; Cowan KH
Mol Pharmacol; 1990 Jun; 37(6):801-9. PubMed ID: 1972772
[TBL] [Abstract][Full Text] [Related]
13. Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection.
Choi K; Frommel TO; Stern RK; Perez CF; Kriegler M; Tsuruo T; Roninson IB
Proc Natl Acad Sci U S A; 1991 Aug; 88(16):7386-90. PubMed ID: 1678523
[TBL] [Abstract][Full Text] [Related]
14. Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833.
Beketic-Oreskovic L; Durán GE; Chen KG; Dumontet C; Sikic BI
J Natl Cancer Inst; 1995 Nov; 87(21):1593-602. PubMed ID: 7563202
[TBL] [Abstract][Full Text] [Related]
15. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.
Roninson IB; Chin JE; Choi KG; Gros P; Housman DE; Fojo A; Shen DW; Gottesman MM; Pastan I
Proc Natl Acad Sci U S A; 1986 Jun; 83(12):4538-42. PubMed ID: 3459187
[TBL] [Abstract][Full Text] [Related]
16. mdr1/P-glycoprotein gene segments analyzed from various human leukemic cell lines exhibiting different multidrug resistance profiles.
Gekeler V; Weger S; Probst H
Biochem Biophys Res Commun; 1990 Jun; 169(2):796-802. PubMed ID: 1972623
[TBL] [Abstract][Full Text] [Related]
17. Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities.
Devault A; Gros P
Mol Cell Biol; 1990 Apr; 10(4):1652-63. PubMed ID: 1969610
[TBL] [Abstract][Full Text] [Related]
18. Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line.
Baas F; Jongsma AP; Broxterman HJ; Arceci RJ; Housman D; Scheffer GL; Riethorst A; van Groenigen M; Nieuwint AW; Joenje H
Cancer Res; 1990 Sep; 50(17):5392-8. PubMed ID: 1974823
[TBL] [Abstract][Full Text] [Related]
19. Sensitivity of K562 human chronic myelogenous leukemia blast cells transfected with a human multidrug resistance cDNA to cytotoxic drugs and differentiating agents.
Hait WN; Choudhury S; Srimatkandada S; Murren JR
J Clin Invest; 1993 May; 91(5):2207-15. PubMed ID: 8098047
[TBL] [Abstract][Full Text] [Related]
20. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene.
Henderson DM; Sifri CD; Rodgers M; Wirth DF; Hendrickson N; Ullman B
Mol Cell Biol; 1992 Jun; 12(6):2855-65. PubMed ID: 1350325
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
