185 related articles for article (PubMed ID: 28973132)
21. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
Yu ZX; Li SH; Evans J; Pillarisetti A; Li H; Li XJ
J Neurosci; 2003 Mar; 23(6):2193-202. PubMed ID: 12657678
[TBL] [Abstract][Full Text] [Related]
22. Bim contributes to the progression of Huntington's disease-associated phenotypes.
Roberts SL; Evans T; Yang Y; Fu Y; Button RW; Sipthorpe RJ; Cowan K; Valionyte E; Anichtchik O; Li H; Lu B; Luo S
Hum Mol Genet; 2020 Jan; 29(2):216-227. PubMed ID: 31813995
[TBL] [Abstract][Full Text] [Related]
23. Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery.
Ceccarelli I; Fiengo P; Remelli R; Miragliotta V; Rossini L; Biotti I; Cappelli A; Petricca L; La Rosa S; Caricasole A; Pollio G; Scali C
Neurobiol Dis; 2016 Feb; 86():41-51. PubMed ID: 26626080
[TBL] [Abstract][Full Text] [Related]
24. A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration.
Lu B; Palacino J
FASEB J; 2013 May; 27(5):1820-9. PubMed ID: 23325320
[TBL] [Abstract][Full Text] [Related]
25. Manifestation of Huntington's disease pathology in human induced pluripotent stem cell-derived neurons.
Nekrasov ED; Vigont VA; Klyushnikov SA; Lebedeva OS; Vassina EM; Bogomazova AN; Chestkov IV; Semashko TA; Kiseleva E; Suldina LA; Bobrovsky PA; Zimina OA; Ryazantseva MA; Skopin AY; Illarioshkin SN; Kaznacheyeva EV; Lagarkova MA; Kiselev SL
Mol Neurodegener; 2016 Apr; 11():27. PubMed ID: 27080129
[TBL] [Abstract][Full Text] [Related]
26. Decreasing Levels of the cdk5 Activators, p25 and p35, Reduces Excitotoxicity in Striatal Neurons.
Park KH; Lu G; Fan J; Raymond LA; Leavitt BR
J Huntingtons Dis; 2012; 1(1):89-96. PubMed ID: 24353748
[TBL] [Abstract][Full Text] [Related]
27. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
[TBL] [Abstract][Full Text] [Related]
28. Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin.
Galan-Rodriguez B; Martin E; Brouillet E; Déglon N; Betuing S; Caboche J
Eur J Neurosci; 2017 Jan; 45(1):198-206. PubMed ID: 27717053
[TBL] [Abstract][Full Text] [Related]
29. N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.
Liu X; Wang CE; Hong Y; Zhao T; Wang G; Gaertig MA; Sun M; Li S; Li XJ
PLoS Genet; 2016 May; 12(5):e1006083. PubMed ID: 27203582
[TBL] [Abstract][Full Text] [Related]
30. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
[TBL] [Abstract][Full Text] [Related]
31. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease.
Yan S; Tu Z; Liu Z; Fan N; Yang H; Yang S; Yang W; Zhao Y; Ouyang Z; Lai C; Yang H; Li L; Liu Q; Shi H; Xu G; Zhao H; Wei H; Pei Z; Li S; Lai L; Li XJ
Cell; 2018 May; 173(4):989-1002.e13. PubMed ID: 29606351
[TBL] [Abstract][Full Text] [Related]
32. The role of IκB kinase complex in the neurobiology of Huntington's disease.
Khoshnan A; Patterson PH
Neurobiol Dis; 2011 Aug; 43(2):305-11. PubMed ID: 21554955
[TBL] [Abstract][Full Text] [Related]
33. Loss-of-Huntingtin in Medial and Lateral Ganglionic Lineages Differentially Disrupts Regional Interneuron and Projection Neuron Subtypes and Promotes Huntington's Disease-Associated Behavioral, Cellular, and Pathological Hallmarks.
Mehler MF; Petronglo JR; Arteaga-Bracho EE; Gulinello ME; Winchester ML; Pichamoorthy N; Young SK; DeJesus CD; Ishtiaq H; Gokhan S; Molero AE
J Neurosci; 2019 Mar; 39(10):1892-1909. PubMed ID: 30626701
[TBL] [Abstract][Full Text] [Related]
34. Huntington aggregates may not predict neuronal death in Huntington's disease.
Kuemmerle S; Gutekunst CA; Klein AM; Li XJ; Li SH; Beal MF; Hersch SM; Ferrante RJ
Ann Neurol; 1999 Dec; 46(6):842-9. PubMed ID: 10589536
[TBL] [Abstract][Full Text] [Related]
35. Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.
Keeler AM; Sapp E; Chase K; Sottosanti E; Danielson E; Pfister E; Stoica L; DiFiglia M; Aronin N; Sena-Esteves M
J Huntingtons Dis; 2016 Oct; 5(3):239-248. PubMed ID: 27689620
[TBL] [Abstract][Full Text] [Related]
36. Human-to-mouse prion-like propagation of mutant huntingtin protein.
Jeon I; Cicchetti F; Cisbani G; Lee S; Li E; Bae J; Lee N; Li L; Im W; Kim M; Kim HS; Oh SH; Kim TA; Ko JJ; Aubé B; Oueslati A; Kim YJ; Song J
Acta Neuropathol; 2016 Oct; 132(4):577-92. PubMed ID: 27221146
[TBL] [Abstract][Full Text] [Related]
37. Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor.
Eddings CR; Arbez N; Akimov S; Geva M; Hayden MR; Ross CA
Neurobiol Dis; 2019 Sep; 129():118-129. PubMed ID: 31108174
[TBL] [Abstract][Full Text] [Related]
38. IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin.
Khoshnan A; Ko J; Tescu S; Brundin P; Patterson PH
PLoS One; 2009 Jun; 4(6):e5768. PubMed ID: 19488402
[TBL] [Abstract][Full Text] [Related]
39. Trehalose rescues glial cell dysfunction in striatal cultures from HD R6/1 mice at early postnatal development.
Perucho J; Gómez A; Muñoz MP; de Yébenes JG; Mena MÁ; Casarejos MJ
Mol Cell Neurosci; 2016 Jul; 74():128-45. PubMed ID: 27236019
[TBL] [Abstract][Full Text] [Related]
40. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
Liot G; Zala D; Pla P; Mottet G; Piel M; Saudou F
J Neurosci; 2013 Apr; 33(15):6298-309. PubMed ID: 23575829
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
