BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 28977920)

  • 1. Chiral platinum (II)-4-(2,3-dihydroxypropyl)- formamide oxo-aporphine (FOA) complexes promote tumor cells apoptosis by directly targeting G-quadruplex DNA
    Qin QP; Qin JL; Chen M; Li YL; Meng T; Zhou J; Liang H; Chen ZF
    Oncotarget; 2017 Sep; 8(37):61982-61997. PubMed ID: 28977920
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis.
    Chen ZF; Qin QP; Qin JL; Zhou J; Li YL; Li N; Liu YC; Liang H
    J Med Chem; 2015 Jun; 58(11):4771-89. PubMed ID: 25988535
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A platinum(II) complex of liriodenine from traditional Chinese medicine (TCM): Cell cycle arrest, cell apoptosis induction and telomerase inhibition activity via G-quadruplex DNA stabilization.
    Li YL; Qin QP; Liu YC; Chen ZF; Liang H
    J Inorg Biochem; 2014 Aug; 137():12-21. PubMed ID: 24798373
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.
    Chen ZF; Qin QP; Qin JL; Liu YC; Huang KB; Li YL; Meng T; Zhang GH; Peng Y; Luo XJ; Liang H
    J Med Chem; 2015 Mar; 58(5):2159-79. PubMed ID: 25650792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interactions of terpyridines and their Pt(II) complexes with G-quadruplex DNAs and telomerase inhibition.
    Wei C; Ren L; Gao N
    Int J Biol Macromol; 2013 Jun; 57():1-8. PubMed ID: 23434432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA.
    Wang P; Leung CH; Ma DL; Yan SC; Che CM
    Chemistry; 2010 Jun; 16(23):6900-11. PubMed ID: 20437426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stabilization of c-myc G-Quadruplex DNA, inhibition of telomerase activity, disruption of mitochondrial functions and tumor cell apoptosis by platinum(II) complex with 9-amino-oxoisoaporphine.
    Qin JL; Qin QP; Wei ZZ; Yu YC; Meng T; Wu CX; Liang YL; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():417-427. PubMed ID: 27597417
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression.
    Wu P; Ma DL; Leung CH; Yan SC; Zhu N; Abagyan R; Che CM
    Chemistry; 2009 Dec; 15(47):13008-21. PubMed ID: 19876976
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel platinum complexes as efficient G-quadruplex DNA binders and telomerase inhibitors.
    Wei C; Wen Y; Wang J
    Int J Biol Macromol; 2013 Apr; 55():185-92. PubMed ID: 23313450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High in vivo antitumor activity of cobalt oxoisoaporphine complexes by targeting G-quadruplex DNA, telomerase and disrupting mitochondrial functions.
    Qin QP; Qin JL; Meng T; Lin WH; Zhang CH; Wei ZZ; Chen JN; Liu YC; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():380-392. PubMed ID: 27597414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl) imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity.
    Qin QP; Chen ZF; Shen WY; Jiang YH; Cao D; Li YL; Xu QM; Liu YC; Huang KB; Liang H
    Eur J Med Chem; 2015 Jan; 89():77-87. PubMed ID: 25462228
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis.
    Zhou XQ; Li Y; Zhang DY; Nie Y; Li ZJ; Gu W; Liu X; Tian JL; Yan SP
    Eur J Med Chem; 2016 May; 114():244-56. PubMed ID: 26994692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW; Promontorio R; Hampel SM; Micco M; Neidle S; Parkinson GN
    J Am Chem Soc; 2012 Feb; 134(5):2723-31. PubMed ID: 22280460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
    Burger AM; Dai F; Schultes CM; Reszka AP; Moore MJ; Double JA; Neidle S
    Cancer Res; 2005 Feb; 65(4):1489-96. PubMed ID: 15735037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preparation of 4-([2,2':6',2″-terpyridin]-4'-yl)-N,N-diethylaniline Ni(II) and Pt(II) complexes and exploration of their in vitro cytotoxic activities.
    Zou HH; Wang L; Long ZX; Qin QP; Song ZK; Xie T; Zhang SH; Liu YC; Lin B; Chen ZF
    Eur J Med Chem; 2016 Jan; 108():1-12. PubMed ID: 26619388
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.
    Xu CX; Shen Y; Hu Q; Zheng YX; Cao Q; Qin PZ; Zhao Y; Ji LN; Mao ZW
    Chem Asian J; 2014 Sep; 9(9):2519-26. PubMed ID: 24996049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, cytotoxicity and DNA-binding levels of new type binuclear platinum(II) complexes.
    Zhang J; Li Y; Sun J; Li W; Gong Y; Zheng X; Cui J; Wang R; Wu J
    Eur J Med Chem; 2009 Nov; 44(11):4772-7. PubMed ID: 19615790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Platinum(II) phenanthroimidazole G-quadruplex ligand induces selective telomere shortening in A549 cancer cells.
    Mancini J; Rousseau P; Castor KJ; Sleiman HF; Autexier C
    Biochimie; 2016 Feb; 121():287-97. PubMed ID: 26724375
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stabilization of G-quadruplex DNA, inhibition of telomerase activity and live cell imaging studies of chiral ruthenium(II) complexes.
    Sun D; Liu Y; Liu D; Zhang R; Yang X; Liu J
    Chemistry; 2012 Apr; 18(14):4285-95. PubMed ID: 22367788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Syntheses of polypyridyl metal complexes and studies of their interaction with quadruplex DNA.
    Stafford VS; Suntharalingam K; Shivalingam A; White AJ; Mann DJ; Vilar R
    Dalton Trans; 2015 Feb; 44(8):3686-700. PubMed ID: 25361228
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.