BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

480 related articles for article (PubMed ID: 28981865)

  • 1. Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.
    Adolph MB; Love RP; Feng Y; Chelico L
    Nucleic Acids Res; 2017 Nov; 45(20):11925-11940. PubMed ID: 28981865
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.
    Hoopes JI; Cortez LM; Mertz TM; Malc EP; Mieczkowski PA; Roberts SA
    Cell Rep; 2016 Feb; 14(6):1273-1282. PubMed ID: 26832400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Competition for DNA binding between the genome protector replication protein A and the genome modifying APOBEC3 single-stranded DNA deaminases.
    Wong L; Sami A; Chelico L
    Nucleic Acids Res; 2022 Nov; 50(21):12039-12057. PubMed ID: 36444883
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.
    McCann JL; Cristini A; Law EK; Lee SY; Tellier M; Carpenter MA; Beghè C; Kim JJ; Sanchez A; Jarvis MC; Stefanovska B; Temiz NA; Bergstrom EN; Salamango DJ; Brown MR; Murphy S; Alexandrov LB; Miller KM; Gromak N; Harris RS
    Nat Genet; 2023 Oct; 55(10):1721-1734. PubMed ID: 37735199
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ancestral APOBEC3B Nuclear Localization Is Maintained in Humans and Apes and Altered in Most Other Old World Primate Species.
    Auerbach AA; Becker JT; Moraes SN; Moghadasi SA; Duda JM; Salamango DJ; Harris RS
    mSphere; 2022 Dec; 7(6):e0045122. PubMed ID: 36374108
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes.
    Sanchez A; Ortega P; Sakhtemani R; Manjunath L; Oh S; Bournique E; Becker A; Kim K; Durfee C; Temiz NA; Chen XS; Harris RS; Lawrence MS; Buisson R
    Nat Commun; 2024 Mar; 15(1):2370. PubMed ID: 38499542
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.
    Carpenter MA; Temiz NA; Ibrahim MA; Jarvis MC; Brown MR; Argyris PP; Brown WL; Starrett GJ; Yee D; Harris RS
    PLoS Genet; 2023 Nov; 19(11):e1011043. PubMed ID: 38033156
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B.
    Hou S; Silvas TV; Leidner F; Nalivaika EA; Matsuo H; Kurt Yilmaz N; Schiffer CA
    J Chem Theory Comput; 2019 Jan; 15(1):637-647. PubMed ID: 30457868
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils.
    Siriwardena SU; Perera MLW; Senevirathne V; Stewart J; Bhagwat AS
    Mol Cell Biol; 2019 Jan; 39(1):. PubMed ID: 30348839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif.
    Land AM; Wang J; Law EK; Aberle R; Kirmaier A; Krupp A; Johnson WE; Harris RS
    Oncotarget; 2015 Nov; 6(37):39969-79. PubMed ID: 26544511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
    Shi K; Carpenter MA; Banerjee S; Shaban NM; Kurahashi K; Salamango DJ; McCann JL; Starrett GJ; Duffy JV; Demir Ö; Amaro RE; Harki DA; Harris RS; Aihara H
    Nat Struct Mol Biol; 2017 Feb; 24(2):131-139. PubMed ID: 27991903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simian Immunodeficiency Virus Vif and Human APOBEC3B Interactions Resemble Those between HIV-1 Vif and Human APOBEC3G.
    Wang J; Shaban NM; Land AM; Brown WL; Harris RS
    J Virol; 2018 Jun; 92(12):. PubMed ID: 29618650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Visualization of uracils created by APOBEC3A using UdgX shows colocalization with RPA at stalled replication forks.
    Stewart JA; Schauer G; Bhagwat AS
    Nucleic Acids Res; 2020 Nov; 48(20):e118. PubMed ID: 33074285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli.
    Bhagwat AS; Hao W; Townes JP; Lee H; Tang H; Foster PL
    Proc Natl Acad Sci U S A; 2016 Feb; 113(8):2176-81. PubMed ID: 26839411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations.
    Butt Y; Sakhtemani R; Mohamad-Ramshan R; Lawrence MS; Bhagwat AS
    Nat Commun; 2024 Mar; 15(1):2369. PubMed ID: 38499553
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.
    Fu Y; Ito F; Zhang G; Fernandez B; Yang H; Chen XS
    Biochem J; 2015 Oct; 471(1):25-35. PubMed ID: 26195824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical Basis of APOBEC3 Deoxycytidine Deaminase Activity on Diverse DNA Substrates.
    Adolph MB; Love RP; Chelico L
    ACS Infect Dis; 2018 Mar; 4(3):224-238. PubMed ID: 29347817
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.
    Lada AG; Waisertreiger IS; Grabow CE; Prakash A; Borgstahl GE; Rogozin IB; Pavlov YI
    PLoS One; 2011; 6(9):e24848. PubMed ID: 21935481
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.
    Warren CJ; Westrich JA; Doorslaer KV; Pyeon D
    Viruses; 2017 Aug; 9(8):. PubMed ID: 28825669
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity.
    Pham P; Calabrese P; Park SJ; Goodman MF
    J Biol Chem; 2011 Jul; 286(28):24931-42. PubMed ID: 21572036
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.