BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 28986121)

  • 1. A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.
    Hong SK; Wu PK; Park JI
    Cell Signal; 2018 Jan; 42():11-20. PubMed ID: 28986121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling.
    Hong SK; Yoon S; Moelling C; Arthan D; Park JI
    J Biol Chem; 2009 Nov; 284(48):33006-18. PubMed ID: 19805545
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Active ERK2 is sufficient to mediate growth arrest and differentiation signaling.
    Wu PK; Hong SK; Yoon SH; Park JI
    FEBS J; 2015 Mar; 282(6):1017-30. PubMed ID: 25639353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway.
    Wu PK; Becker A; Park JI
    Int J Mol Sci; 2020 Jul; 21(15):. PubMed ID: 32751750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M; Kasprzycka M; Liu X; Raghunath PN; Wlodarski P; Wasik MA
    Oncogene; 2007 Feb; 26(6):813-21. PubMed ID: 16909118
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells.
    Hong SK; Kim JH; Lin MF; Park JI
    Exp Cell Res; 2011 Nov; 317(18):2671-82. PubMed ID: 21871886
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ERK1/2 can feedback-regulate cellular MEK1/2 levels.
    Hong SK; Wu PK; Karkhanis M; Park JI
    Cell Signal; 2015 Oct; 27(10):1939-48. PubMed ID: 26163823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels.
    Kim JH; Hong SK; Wu PK; Richards AL; Jackson WT; Park JI
    Exp Cell Res; 2014 Oct; 327(2):340-52. PubMed ID: 25128814
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors.
    Dworakowska D; Wlodek E; Leontiou CA; Igreja S; Cakir M; Teng M; Prodromou N; Góth MI; Grozinsky-Glasberg S; Gueorguiev M; Kola B; Korbonits M; Grossman AB
    Endocr Relat Cancer; 2009 Dec; 16(4):1329-38. PubMed ID: 19620247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).
    Dwivedi Y; Rizavi HS; Zhang H; Roberts RC; Conley RR; Pandey GN
    Int J Neuropsychopharmacol; 2009 Nov; 12(10):1337-54. PubMed ID: 19835659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Total ERK1/2 activity regulates cell proliferation.
    Lefloch R; Pouysségur J; Lenormand P
    Cell Cycle; 2009 Mar; 8(5):705-11. PubMed ID: 19242111
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors.
    Thottassery JV; Sun Y; Westbrook L; Rentz SS; Manuvakhova M; Qu Z; Samuel S; Upshaw R; Cunningham A; Kern FG
    Cancer Res; 2004 Jul; 64(13):4637-47. PubMed ID: 15231676
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs response of cancer cells to DR5-mediated apoptosis and T cell-induced killing.
    Oh YT; Deng J; Yue P; Owonikoko TK; Khuri FR; Sun SY
    Oncogene; 2016 Jan; 35(4):459-67. PubMed ID: 25867065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation.
    Crowe MS; Zavorotinskaya T; Voliva CF; Shirley MD; Wang Y; Ruddy DA; Rakiec DP; Engelman JA; Stuart DD; Freeman AK
    Mol Cancer Res; 2021 Jun; 19(6):1063-1075. PubMed ID: 33707308
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals.
    von Gise A; Lorenz P; Wellbrock C; Hemmings B; Berberich-Siebelt F; Rapp UR; Troppmair J
    Mol Cell Biol; 2001 Apr; 21(7):2324-36. PubMed ID: 11259582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reciprocal regulation of PKA and Rac signaling.
    Bachmann VA; Riml A; Huber RG; Baillie GS; Liedl KR; Valovka T; Stefan E
    Proc Natl Acad Sci U S A; 2013 May; 110(21):8531-6. PubMed ID: 23657011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway.
    Shen B; Kwan HY; Ma X; Wong CO; Du J; Huang Y; Yao X
    J Biol Chem; 2011 Jun; 286(22):19439-45. PubMed ID: 21487005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.
    Shin J; Yang J; Lee JC; Baek KH
    Cell Signal; 2013 Dec; 25(12):2540-7. PubMed ID: 23993963
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Chappell WH; Abrams SL; Wong EW; Chang F; Lehmann B; Terrian DM; Milella M; Tafuri A; Stivala F; Libra M; Basecke J; Evangelisti C; Martelli AM; Franklin RA
    Biochim Biophys Acta; 2007 Aug; 1773(8):1263-84. PubMed ID: 17126425
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.
    Gysin S; Lee SH; Dean NM; McMahon M
    Cancer Res; 2005 Jun; 65(11):4870-80. PubMed ID: 15930308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.