These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 28988034)

  • 1. The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43.
    Li HR; Chen TC; Hsiao CL; Shi L; Chou CY; Huang JR
    Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):214-223. PubMed ID: 28988034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
    Li HR; Chiang WC; Chou PC; Wang WJ; Huang JR
    J Biol Chem; 2018 Apr; 293(16):6090-6098. PubMed ID: 29511089
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Zn
    Preethi S; Bharathi V; Patel BK
    Int J Biol Macromol; 2021 Apr; 176():186-200. PubMed ID: 33577819
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
    Mompeán M; Romano V; Pantoja-Uceda D; Stuani C; Baralle FE; Buratti E; Laurents DV
    J Biol Chem; 2017 Jul; 292(28):11992-12006. PubMed ID: 28566288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-43
    Girdhar A; Bharathi V; Tiwari VR; Abhishek S; Deeksha W; Mahawar US; Raju G; Singh SK; Prabusankar G; Rajakumara E; Patel BK
    Int J Biol Macromol; 2020 Mar; 147():117-130. PubMed ID: 31917988
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
    Conicella AE; Dignon GL; Zerze GH; Schmidt HB; D'Ordine AM; Kim YC; Rohatgi R; Ayala YM; Mittal J; Fawzi NL
    Proc Natl Acad Sci U S A; 2020 Mar; 117(11):5883-5894. PubMed ID: 32132204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain.
    Haider R; Shipley B; Surewicz K; Hinczewski M; Surewicz WK
    Protein Sci; 2024 Oct; 33(10):e5179. PubMed ID: 39302099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43
    Zeng J; Tang Y; Dong X; Li F; Wei G
    Proteins; 2024 Sep; 92(9):1059-1069. PubMed ID: 36841957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Uncovering Intermolecular Interactions Driving the Liquid-Liquid Phase Separation of the TDP-43 Low-Complexity Domain via Atomistic Dimerization Simulations.
    Tang H; Sun Y; Wang L; Ke PC; Ding F
    J Chem Inf Model; 2024 Oct; 64(19):7590-7601. PubMed ID: 39342654
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
    Wang A; Conicella AE; Schmidt HB; Martin EW; Rhoads SN; Reeb AN; Nourse A; Ramirez Montero D; Ryan VH; Rohatgi R; Shewmaker F; Naik MT; Mittag T; Ayala YM; Fawzi NL
    EMBO J; 2018 Mar; 37(5):. PubMed ID: 29438978
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
    Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
    Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphomimetic substitutions in TDP-43's transiently α-helical region suppress phase separation.
    Haider R; Penumutchu S; Boyko S; Surewicz WK
    Biophys J; 2024 Feb; 123(3):361-373. PubMed ID: 38178578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain.
    Babinchak WM; Haider R; Dumm BK; Sarkar P; Surewicz K; Choi JK; Surewicz WK
    J Biol Chem; 2019 Apr; 294(16):6306-6317. PubMed ID: 30814253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biophysical characterization of the phase separation of TDP-43 devoid of the C-terminal domain.
    Staderini T; Bigi A; Lagrève C; Marzi I; Bemporad F; Chiti F
    Cell Mol Biol Lett; 2024 Jul; 29(1):104. PubMed ID: 38997630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
    Conicella AE; Zerze GH; Mittal J; Fawzi NL
    Structure; 2016 Sep; 24(9):1537-49. PubMed ID: 27545621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
    French RL; Grese ZR; Aligireddy H; Dhavale DD; Reeb AN; Kedia N; Kotzbauer PT; Bieschke J; Ayala YM
    J Biol Chem; 2019 Apr; 294(17):6696-6709. PubMed ID: 30824544
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TDP-43 NTD can be induced while CTD is significantly enhanced by ssDNA to undergo liquid-liquid phase separation.
    Wang L; Kang J; Lim L; Wei Y; Song J
    Biochem Biophys Res Commun; 2018 May; 499(2):189-195. PubMed ID: 29555476
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.
    Lim L; Wei Y; Lu Y; Song J
    PLoS Biol; 2016 Jan; 14(1):e1002338. PubMed ID: 26735904
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization.
    Prasad A; Sivalingam V; Bharathi V; Girdhar A; Patel BK
    Biochimie; 2018 Jul; 150():76-87. PubMed ID: 29751083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis.
    Prasad A; Bharathi V; Sivalingam V; Girdhar A; Patel BK
    Front Mol Neurosci; 2019; 12():25. PubMed ID: 30837838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.