471 related articles for article (PubMed ID: 28988823)
1. FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia.
Lan T; Morgan DA; Rahmouni K; Sonoda J; Fu X; Burgess SC; Holland WL; Kliewer SA; Mangelsdorf DJ
Cell Metab; 2017 Nov; 26(5):709-718.e3. PubMed ID: 28988823
[TBL] [Abstract][Full Text] [Related]
2. Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients.
Gallego-Escuredo JM; Gómez-Ambrosi J; Catalan V; Domingo P; Giralt M; Frühbeck G; Villarroya F
Int J Obes (Lond); 2015 Jan; 39(1):121-9. PubMed ID: 24813368
[TBL] [Abstract][Full Text] [Related]
3. Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.
Kolumam G; Chen MZ; Tong R; Zavala-Solorio J; Kates L; van Bruggen N; Ross J; Wyatt SK; Gandham VD; Carano RA; Dunshee DR; Wu AL; Haley B; Anderson K; Warming S; Rairdan XY; Lewin-Koh N; Zhang Y; Gutierrez J; Baruch A; Gelzleichter TR; Stevens D; Rajan S; Bainbridge TW; Vernes JM; Meng YG; Ziai J; Soriano RH; Brauer MJ; Chen Y; Stawicki S; Kim HS; Comps-Agrar L; Luis E; Spiess C; Wu Y; Ernst JA; McGuinness OP; Peterson AS; Sonoda J
EBioMedicine; 2015 Jul; 2(7):730-43. PubMed ID: 26288846
[TBL] [Abstract][Full Text] [Related]
4. FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.
Chen MZ; Chang JC; Zavala-Solorio J; Kates L; Thai M; Ogasawara A; Bai X; Flanagan S; Nunez V; Phamluong K; Ziai J; Newman R; Warming S; Kolumam G; Sonoda J
Mol Metab; 2017 Nov; 6(11):1454-1467. PubMed ID: 29107292
[TBL] [Abstract][Full Text] [Related]
5. Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.
Foltz IN; Hu S; King C; Wu X; Yang C; Wang W; Weiszmann J; Stevens J; Chen JS; Nuanmanee N; Gupte J; Komorowski R; Sekirov L; Hager T; Arora T; Ge H; Baribault H; Wang F; Sheng J; Karow M; Wang M; Luo Y; McKeehan W; Wang Z; Véniant MM; Li Y
Sci Transl Med; 2012 Nov; 4(162):162ra153. PubMed ID: 23197570
[TBL] [Abstract][Full Text] [Related]
6. Reduced levels of serum FGF19 and impaired expression of receptors for endocrine FGFs in adipose tissue from HIV-infected patients.
Gallego-Escuredo JM; Domingo P; Gutiérrez Mdel M; Mateo MG; Cabeza MC; Fontanet A; Vidal F; Domingo JC; Giralt M; Villarroya F
J Acquir Immune Defic Syndr; 2012 Dec; 61(5):527-34. PubMed ID: 23187887
[TBL] [Abstract][Full Text] [Related]
7. Chronic high-sucrose diet increases fibroblast growth factor 21 production and energy expenditure in mice.
Maekawa R; Seino Y; Ogata H; Murase M; Iida A; Hosokawa K; Joo E; Harada N; Tsunekawa S; Hamada Y; Oiso Y; Inagaki N; Hayashi Y; Arima H
J Nutr Biochem; 2017 Nov; 49():71-79. PubMed ID: 28886439
[TBL] [Abstract][Full Text] [Related]
8. Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions.
Min X; Weiszmann J; Johnstone S; Wang W; Yu X; Romanow W; Thibault S; Li Y; Wang Z
J Biol Chem; 2018 Sep; 293(38):14678-14688. PubMed ID: 30068552
[TBL] [Abstract][Full Text] [Related]
9. Relevant use of Klotho in FGF19 subfamily signaling system in vivo.
Tomiyama K; Maeda R; Urakawa I; Yamazaki Y; Tanaka T; Ito S; Nabeshima Y; Tomita T; Odori S; Hosoda K; Nakao K; Imura A; Nabeshima Y
Proc Natl Acad Sci U S A; 2010 Jan; 107(4):1666-71. PubMed ID: 20080590
[TBL] [Abstract][Full Text] [Related]
10. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.
Yang C; Jin C; Li X; Wang F; McKeehan WL; Luo Y
PLoS One; 2012; 7(3):e33870. PubMed ID: 22442730
[TBL] [Abstract][Full Text] [Related]
11. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.
Kurosu H; Choi M; Ogawa Y; Dickson AS; Goetz R; Eliseenkova AV; Mohammadi M; Rosenblatt KP; Kliewer SA; Kuro-O M
J Biol Chem; 2007 Sep; 282(37):26687-26695. PubMed ID: 17623664
[TBL] [Abstract][Full Text] [Related]
12. Klotho and fibroblast growth factors 19 and 21 serum concentrations in children and adolescents with normal body weight and obesity and their associations with metabolic parameters.
Socha-Banasiak A; Michalak A; Pacześ K; Gaj Z; Fendler W; Socha A; Głowacka E; Kapka K; Gołąbek V; Czkwianianc E
BMC Pediatr; 2020 Jun; 20(1):294. PubMed ID: 32546231
[TBL] [Abstract][Full Text] [Related]
13. Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21.
Moure R; Cairó M; Morón-Ros S; Quesada-López T; Campderrós L; Cereijo R; Hernáez A; Villarroya F; Giralt M
Am J Physiol Endocrinol Metab; 2021 Apr; 320(4):E822-E834. PubMed ID: 33615874
[TBL] [Abstract][Full Text] [Related]
14. FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.
Owen BM; Ding X; Morgan DA; Coate KC; Bookout AL; Rahmouni K; Kliewer SA; Mangelsdorf DJ
Cell Metab; 2014 Oct; 20(4):670-7. PubMed ID: 25130400
[TBL] [Abstract][Full Text] [Related]
15. Fibroblast growth factor 21, fibroblast growth factor receptor 1, and β-Klotho expression in bovine growth hormone transgenic and growth hormone receptor knockout mice.
Brooks NE; Hjortebjerg R; Henry BE; List EO; Kopchick JJ; Berryman DE
Growth Horm IGF Res; 2016; 30-31():22-30. PubMed ID: 27585733
[TBL] [Abstract][Full Text] [Related]
16. Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity.
Samms RJ; Cheng CC; Kharitonenkov A; Gimeno RE; Adams AC
Endocrinology; 2016 Apr; 157(4):1467-80. PubMed ID: 26901091
[TBL] [Abstract][Full Text] [Related]
17. Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity.
Agrawal A; Parlee S; Perez-Tilve D; Li P; Pan J; Mroz PA; Kruse Hansen AM; Andersen B; Finan B; Kharitonenkov A; DiMarchi RD
Mol Metab; 2018 Jul; 13():45-55. PubMed ID: 29789271
[TBL] [Abstract][Full Text] [Related]
18. FGF19 subfamily members: FGF19 and FGF21.
Dolegowska K; Marchelek-Mysliwiec M; Nowosiad-Magda M; Slawinski M; Dolegowska B
J Physiol Biochem; 2019 Jun; 75(2):229-240. PubMed ID: 30927227
[TBL] [Abstract][Full Text] [Related]
19. MicroRNA-34a and Impaired FGF19/21 Signaling in Obesity.
Fu T; Kemper JK
Vitam Horm; 2016; 101():175-96. PubMed ID: 27125742
[TBL] [Abstract][Full Text] [Related]
20. Interactions Between the Gravitostat and the Fibroblast Growth Factor System for the Regulation of Body Weight.
Palsdottir V; Windahl SH; Hägg DA; Keantar H; Bellman J; Buchanan A; Vaughan TJ; Lindén D; Jansson JO; Ohlsson C
Endocrinology; 2019 May; 160(5):1057-1064. PubMed ID: 30888399
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
