226 related articles for article (PubMed ID: 28988886)
1. The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1.
Vilaça R; Barros I; Matmati N; Silva E; Martins T; Teixeira V; Hannun YA; Costa V
Biochim Biophys Acta Mol Basis Dis; 2018 Jan; 1864(1):79-88. PubMed ID: 28988886
[TBL] [Abstract][Full Text] [Related]
2. Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.
Vilaça R; Silva E; Nadais A; Teixeira V; Matmati N; Gaifem J; Hannun YA; Sá Miranda MC; Costa V
Mol Microbiol; 2014 Feb; 91(3):438-51. PubMed ID: 24286211
[TBL] [Abstract][Full Text] [Related]
3. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells.
Barbosa AD; Osório H; Sims KJ; Almeida T; Alves M; Bielawski J; Amorim MA; Moradas-Ferreira P; Hannun YA; Costa V
Mol Microbiol; 2011 Jul; 81(2):515-27. PubMed ID: 21707788
[TBL] [Abstract][Full Text] [Related]
4. Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.
Pohlers S; Martin R; Krüger T; Hellwig D; Hänel F; Kniemeyer O; Saluz HP; Van Dijck P; Ernst JF; Brakhage A; Mühlschlegel FA; Kurzai O
mBio; 2017 Jan; 8(1):. PubMed ID: 28143980
[TBL] [Abstract][Full Text] [Related]
5. Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.
Malathi K; Higaki K; Tinkelenberg AH; Balderes DA; Almanzar-Paramio D; Wilcox LJ; Erdeniz N; Redican F; Padamsee M; Liu Y; Khan S; Alcantara F; Carstea ED; Morris JA; Sturley SL
J Cell Biol; 2004 Feb; 164(4):547-56. PubMed ID: 14970192
[TBL] [Abstract][Full Text] [Related]
6. Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential.
Hammond N; Snider J; Stagljar I; Mitchell K; Lagutin K; Jessulat M; Babu M; Teesdale-Spittle PH; Sheridan JP; Sturley SL; Munkacsi AB
Genetics; 2023 Aug; 225(1):. PubMed ID: 37440478
[TBL] [Abstract][Full Text] [Related]
7. Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.
Yabuki Y; Ikeda A; Araki M; Kajiwara K; Mizuta K; Funato K
Genetics; 2019 May; 212(1):175-186. PubMed ID: 30824472
[TBL] [Abstract][Full Text] [Related]
8. An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease.
Munkacsi AB; Chen FW; Brinkman MA; Higaki K; Gutiérrez GD; Chaudhari J; Layer JV; Tong A; Bard M; Boone C; Ioannou YA; Sturley SL
J Biol Chem; 2011 Jul; 286(27):23842-51. PubMed ID: 21489983
[TBL] [Abstract][Full Text] [Related]
9. Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells.
Teixeira V; Medeiros TC; Vilaça R; Pereira AT; Chaves SR; Côrte-Real M; Moradas-Ferreira P; Costa V
Cell Signal; 2015 Sep; 27(9):1840-9. PubMed ID: 26079297
[TBL] [Abstract][Full Text] [Related]
10. ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis.
Brown RDR; Mahawar U; Wattenberg BW; Spiegel S
J Lipid Res; 2024 Jun; 65(6):100556. PubMed ID: 38719150
[TBL] [Abstract][Full Text] [Related]
11. Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1.
Martins TS; Costa RS; Vilaça R; Lemos C; Teixeira V; Pereira C; Costa V
Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047194
[TBL] [Abstract][Full Text] [Related]
12. FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
Newton J; Hait NC; Maceyka M; Colaco A; Maczis M; Wassif CA; Cougnoux A; Porter FD; Milstien S; Platt N; Platt FM; Spiegel S
FASEB J; 2017 Apr; 31(4):1719-1730. PubMed ID: 28082351
[TBL] [Abstract][Full Text] [Related]
13. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
[TBL] [Abstract][Full Text] [Related]
14. A novel Sit4 phosphatase complex is involved in the response to ceramide stress in yeast.
Woodacre A; Lone MA; Jablonowski D; Schneiter R; Giorgini F; Schaffrath R
Oxid Med Cell Longev; 2013; 2013():129645. PubMed ID: 24082981
[TBL] [Abstract][Full Text] [Related]
15. Niemann-Pick type C disease: The atypical sphingolipidosis.
Newton J; Milstien S; Spiegel S
Adv Biol Regul; 2018 Dec; 70():82-88. PubMed ID: 30205942
[TBL] [Abstract][Full Text] [Related]
16. The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.
Swinnen E; Wilms T; Idkowiak-Baldys J; Smets B; De Snijder P; Accardo S; Ghillebert R; Thevissen K; Cammue B; De Vos D; Bielawski J; Hannun YA; Winderickx J
Mol Biol Cell; 2014 Jan; 25(1):196-211. PubMed ID: 24196832
[TBL] [Abstract][Full Text] [Related]
17. Sng1 associates with Nce102 to regulate the yeast Pkh-Ypk signalling module in response to sphingolipid status.
García-Marqués S; Randez-Gil F; Dupont S; Garre E; Prieto JA
Biochim Biophys Acta; 2016 Jun; 1863(6 Pt A):1319-33. PubMed ID: 27033517
[TBL] [Abstract][Full Text] [Related]
18. Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C.
Colaco A; Fernández-Suárez ME; Shepherd D; Gal L; Bibi C; Chuartzman S; Diot A; Morten K; Eden E; Porter FD; Poulton J; Platt N; Schuldiner M; Platt FM
Life Sci Alliance; 2020 Jul; 3(7):. PubMed ID: 32487688
[TBL] [Abstract][Full Text] [Related]
19. Sit4 Genetically Interacts with Vps27 to Regulate Mitochondrial Function and Lifespan in
Martins TS; Correia M; Pinheiro D; Lemos C; Mendes MV; Pereira C; Costa V
Cells; 2024 Apr; 13(8):. PubMed ID: 38667270
[TBL] [Abstract][Full Text] [Related]
20. The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.
Liu K; Zhang X; Lester RL; Dickson RC
J Biol Chem; 2005 Jun; 280(24):22679-87. PubMed ID: 15840588
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]