BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 29016844)

  • 1. PIK3CB/p110β is a selective survival factor for glioblastoma.
    Pridham KJ; Le L; Guo S; Varghese RT; Algino S; Liang Y; Fajardin R; Rodgers CM; Simonds GR; Kelly DF; Sheng Z
    Neuro Oncol; 2018 Mar; 20(4):494-505. PubMed ID: 29016844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation.
    Karlsson T; Krakstad C; Tangen IL; Hoivik EA; Pollock PM; Salvesen HB; Lewis AE
    Oncotarget; 2017 Jan; 8(3):3881-3894. PubMed ID: 28002804
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Survival kinase genes present prognostic significance in glioblastoma.
    Varghese RT; Liang Y; Guan T; Franck CT; Kelly DF; Sheng Z
    Oncotarget; 2016 Apr; 7(15):20140-51. PubMed ID: 26956052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition.
    Zhao HF; Wang J; Jiang HR; Chen ZP; To SS
    J Exp Clin Cancer Res; 2016 May; 35():78. PubMed ID: 27176481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Class I Phosphoinositide 3-Kinase
    Mazloumi Gavgani F; Smith Arnesen V; Jacobsen RG; Krakstad C; Hoivik EA; Lewis AE
    Int J Mol Sci; 2018 Dec; 19(12):. PubMed ID: 30544563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme.
    Aguila B; Morris AB; Spina R; Bar E; Schraner J; Vinkler R; Sohn JW; Welford SM
    Cancer Lett; 2019 Oct; 462():33-42. PubMed ID: 31377205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER
    Hosford SR; Dillon LM; Bouley SJ; Rosati R; Yang W; Chen VS; Demidenko E; Morra RP; Miller TW
    Clin Cancer Res; 2017 Jun; 23(11):2795-2805. PubMed ID: 27903677
    [No Abstract]   [Full Text] [Related]  

  • 8. The Role of Class IA Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunits in Glioblastoma.
    Pridham KJ; Varghese RT; Sheng Z
    Front Oncol; 2017; 7():312. PubMed ID: 29326882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PTEN-deficient cancers depend on PIK3CB.
    Wee S; Wiederschain D; Maira SM; Loo A; Miller C; deBeaumont R; Stegmeier F; Yao YM; Lengauer C
    Proc Natl Acad Sci U S A; 2008 Sep; 105(35):13057-62. PubMed ID: 18755892
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.
    Höland K; Boller D; Hagel C; Dolski S; Treszl A; Pardo OE; Cwiek P; Salm F; Leni Z; Shepherd PR; Styp-Rekowska B; Djonov V; von Bueren AO; Frei K; Arcaro A
    PLoS One; 2014; 9(4):e94132. PubMed ID: 24718026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An miR-340-5p-macrophage feedback loop modulates the progression and tumor microenvironment of glioblastoma multiforme.
    Liu Y; Li X; Zhang Y; Wang H; Rong X; Peng J; He L; Peng Y
    Oncogene; 2019 Dec; 38(49):7399-7415. PubMed ID: 31427735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas.
    Xie S; Ni J; McFaline-Figueroa JR; Wang Y; Bronson RT; Ligon KL; Wen PY; Roberts TM; Zhao JJ
    Cell Rep; 2020 Sep; 32(13):108196. PubMed ID: 32997991
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    Fink MA; Paland H; Herzog S; Grube M; Vogelgesang S; Weitmann K; Bialke A; Hoffmann W; Rauch BH; Schroeder HWS; Bien-Möller S
    Clin Cancer Res; 2019 May; 25(9):2874-2886. PubMed ID: 30670496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activity of any class IA PI3K isoform can sustain cell proliferation and survival.
    Foukas LC; Berenjeno IM; Gray A; Khwaja A; Vanhaesebroeck B
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11381-6. PubMed ID: 20534549
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeted inhibition of phosphatidyl inositol-3-kinase p110β, but not p110α, enhances apoptosis and sensitivity to paclitaxel in chemoresistant ovarian cancers.
    Jeong JY; Kim KS; Moon JS; Song JA; Choi SH; Kim KI; Kim TH; An HJ
    Apoptosis; 2013 Apr; 18(4):509-20. PubMed ID: 23371322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of a novel p110β-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells.
    He C; Duan S; Dong L; Wang Y; Hu Q; Liu C; Forrest ML; Holzbeierlein JM; Han S; Li B
    Prostate; 2017 Aug; 77(11):1187-1198. PubMed ID: 28631436
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.
    Utermark T; Schmit F; Lee SH; Gao X; Schaffhausen BS; Roberts TM
    J Virol; 2014 Sep; 88(18):10673-9. PubMed ID: 24991009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand-selective signal transduction by two endogenous GnRH isoforms involves biased activation of the class I PI3K catalytic subunits p110β, p110γ, and p110δ in pituitary gonadotropes and somatotropes.
    Pemberton JG; Stafford JL; Chang JP
    Endocrinology; 2015 Jan; 156(1):218-30. PubMed ID: 25343277
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo.
    Cen B; Wei Y; Huang W; Teng M; He S; Li J; Wang W; He G; Bai X; Liu X; Yuan Y; Pan X; Ji A
    Mol Ther Nucleic Acids; 2018 Dec; 13():220-232. PubMed ID: 30312846
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p110α and p110β isoforms of PI3K are involved in protection against H
    Singh P; Bano N; Hossain MM; Basit R; Dar MJ
    Breast Cancer; 2019 May; 26(3):378-385. PubMed ID: 30499025
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.