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2. SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints. Dong Y; Zhao X; Feng X; Zhou Y; Yan X; Zhang Y; Bu J; Zhan D; Hayashi Y; Zhang Y; Xu Z; Huang R; Wang J; Zhao T; Xiao Z; Ju Z; Andreassen PR; Wang QF; Chen W; Huang G Leukemia; 2019 Nov; 33(11):2585-2598. PubMed ID: 30967619 [TBL] [Abstract][Full Text] [Related]
3. Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells. Sheng Y; Ji Z; Zhao H; Wang J; Cheng C; Xu W; Wang X; He Y; Liu K; Li L; Voeltzel T; Maguer-Satta V; Gao WQ; Zhu HH Cell Prolif; 2019 Jul; 52(4):e12611. PubMed ID: 31054182 [TBL] [Abstract][Full Text] [Related]
4. SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia. Bu J; Chen A; Yan X; He F; Dong Y; Zhou Y; He J; Zhan D; Lin P; Hayashi Y; Sun Y; Zhang Y; Xiao Z; Grimes HL; Wang QF; Huang G Leukemia; 2018 Apr; 32(4):890-899. PubMed ID: 29249820 [TBL] [Abstract][Full Text] [Related]
5. Roles of SETD2 in Leukemia-Transcription, DNA-Damage, and Beyond. Skucha A; Ebner J; Grebien F Int J Mol Sci; 2019 Feb; 20(5):. PubMed ID: 30818762 [TBL] [Abstract][Full Text] [Related]
6. The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). Berthelet J; Michail C; Bui LC; Le Coadou L; Sirri V; Wang L; Dulphy N; Dupret JM; Chomienne C; Guidez F; Rodrigues-Lima F Mol Pharmacol; 2021 Sep; 100(3):283-294. PubMed ID: 34266924 [TBL] [Abstract][Full Text] [Related]
7. High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma. Ho TH; Park IY; Zhao H; Tong P; Champion MD; Yan H; Monzon FA; Hoang A; Tamboli P; Parker AS; Joseph RW; Qiao W; Dykema K; Tannir NM; Castle EP; Nunez-Nateras R; Teh BT; Wang J; Walker CL; Hung MC; Jonasch E Oncogene; 2016 Mar; 35(12):1565-74. PubMed ID: 26073078 [TBL] [Abstract][Full Text] [Related]
8. SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle. Gautam D; Johnson BA; Mac M; Moody CA PLoS Pathog; 2018 Oct; 14(10):e1007367. PubMed ID: 30312361 [TBL] [Abstract][Full Text] [Related]
9. Acquired SETD2 mutation and impaired CREB1 activation confer cisplatin resistance in metastatic non-small cell lung cancer. Kim IK; McCutcheon JN; Rao G; Liu SV; Pommier Y; Skrzypski M; Zhang YW; Giaccone G Oncogene; 2019 Jan; 38(2):180-193. PubMed ID: 30093630 [TBL] [Abstract][Full Text] [Related]
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11. Genetic polymorphisms of histone methyltransferase SETD2 predicts prognosis and chemotherapy response in Chinese acute myeloid leukemia patients. Wang S; Yuan X; Liu Y; Zhu K; Chen P; Yan H; Zhang D; Li X; Zeng H; Zhao X; Chen X; Zhou G; Cao S J Transl Med; 2019 Mar; 17(1):101. PubMed ID: 30922329 [TBL] [Abstract][Full Text] [Related]
12. SETD2 alterations and histone H3K36 trimethylation in phyllodes tumor of breast. Tsang JY; Lai ST; Ni YB; Shao Y; Poon IK; Kwan JS; Chow C; Shea KH; Tse GM Breast Cancer Res Treat; 2021 Jun; 187(2):339-347. PubMed ID: 33844099 [TBL] [Abstract][Full Text] [Related]
13. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. Feng Z; Yao Y; Zhou C; Chen F; Wu F; Wei L; Liu W; Dong S; Redell M; Mo Q; Song Y J Hematol Oncol; 2016 Mar; 9():24. PubMed ID: 26970896 [TBL] [Abstract][Full Text] [Related]
14. Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation. Rajagopalan KN; Chen X; Weinberg DN; Chen H; Majewski J; Allis CD; Lu C Proc Natl Acad Sci U S A; 2021 Mar; 118(9):. PubMed ID: 33619101 [TBL] [Abstract][Full Text] [Related]
15. Identification of functional cooperative mutations of SETD2 in human acute leukemia. Zhu X; He F; Zeng H; Ling S; Chen A; Wang Y; Yan X; Wei W; Pang Y; Cheng H; Hua C; Zhang Y; Yang X; Lu X; Cao L; Hao L; Dong L; Zou W; Wu J; Li X; Zheng S; Yan J; Zhou J; Zhang L; Mi S; Wang X; Zhang L; Zou Y; Chen Y; Geng Z; Wang J; Zhou J; Liu X; Wang J; Yuan W; Huang G; Cheng T; Wang QF Nat Genet; 2014 Mar; 46(3):287-93. PubMed ID: 24509477 [TBL] [Abstract][Full Text] [Related]
16. SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. Zhu K; Lei PJ; Ju LG; Wang X; Huang K; Yang B; Shao C; Zhu Y; Wei G; Fu XD; Li L; Wu M Nucleic Acids Res; 2017 Jan; 45(1):92-105. PubMed ID: 27614073 [TBL] [Abstract][Full Text] [Related]
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