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7. Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies. Bernasconi-Elias P; Hu T; Jenkins D; Firestone B; Gans S; Kurth E; Capodieci P; Deplazes-Lauber J; Petropoulos K; Thiel P; Ponsel D; Hee Choi S; LeMotte P; London A; Goetcshkes M; Nolin E; Jones MD; Slocum K; Kluk MJ; Weinstock DM; Christodoulou A; Weinberg O; Jaehrling J; Ettenberg SA; Buckler A; Blacklow SC; Aster JC; Fryer CJ Oncogene; 2016 Nov; 35(47):6077-6086. PubMed ID: 27157619 [TBL] [Abstract][Full Text] [Related]
8. Notch protection against apoptosis in T-ALL cells mediated by GIMAP5. Chadwick N; Zeef L; Portillo V; Boros J; Hoyle S; van Doesburg JC; Buckle AM Blood Cells Mol Dis; 2010 Oct; 45(3):201-9. PubMed ID: 20817506 [TBL] [Abstract][Full Text] [Related]
9. NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Wang H; Zang C; Taing L; Arnett KL; Wong YJ; Pear WS; Blacklow SC; Liu XS; Aster JC Proc Natl Acad Sci U S A; 2014 Jan; 111(2):705-10. PubMed ID: 24374627 [TBL] [Abstract][Full Text] [Related]
10. High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia. Chiang MY; Wang Q; Gormley AC; Stein SJ; Xu L; Shestova O; Aster JC; Pear WS Blood; 2016 Nov; 128(18):2229-2240. PubMed ID: 27670423 [TBL] [Abstract][Full Text] [Related]
11. FHL1C induces apoptosis in Notch1-dependent T-ALL cells through an interaction with RBP-J. Fu W; Wang K; Zhao JL; Yu HC; Li SZ; Lin Y; Liang L; Huang SY; Liang YM; Han H; Qin HY BMC Cancer; 2014 Jun; 14():463. PubMed ID: 24952875 [TBL] [Abstract][Full Text] [Related]
12. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525 [TBL] [Abstract][Full Text] [Related]
14. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia. Lin S; Tian L; Shen H; Gu Y; Li JL; Chen Z; Sun X; You MJ; Wu L Oncogene; 2013 Oct; 32(40):4845-53. PubMed ID: 23108395 [TBL] [Abstract][Full Text] [Related]
15. T-ALL pathogenesis requires a NOTCH1-driven MYC enhancer. Cancer Discov; 2014 Nov; 4(11):OF17. PubMed ID: 25367958 [TBL] [Abstract][Full Text] [Related]
16. Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias. Rakowski LA; Garagiola DD; Li CM; Decker M; Caruso S; Jones M; Kuick R; Cierpicki T; Maillard I; Chiang MY Cancer Res; 2013 Jan; 73(2):930-41. PubMed ID: 23161489 [TBL] [Abstract][Full Text] [Related]
17. Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis. Ruan ZB; Fu XL; Li W; Ye J; Wang RZ; Zhu L Biomed Pharmacother; 2016 Dec; 84():666-673. PubMed ID: 27697639 [TBL] [Abstract][Full Text] [Related]
18. Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia. Palomero T; Ferrando A Clin Lymphoma Myeloma; 2009; 9 Suppl 3(Suppl 3):S205-10. PubMed ID: 19778842 [TBL] [Abstract][Full Text] [Related]
19. Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1. Matsushita K; Kitamura K; Rahmutulla B; Tanaka N; Ishige T; Satoh M; Hoshino T; Miyagi S; Mori T; Itoga S; Shimada H; Tomonaga T; Kito M; Nakajima-Takagi Y; Kubo S; Nakaseko C; Hatano M; Miki T; Matsuo M; Fukuyo M; Kaneda A; Iwama A; Nomura F Oncotarget; 2015 Mar; 6(7):5102-17. PubMed ID: 25671302 [TBL] [Abstract][Full Text] [Related]
20. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Weng AP; Millholland JM; Yashiro-Ohtani Y; Arcangeli ML; Lau A; Wai C; Del Bianco C; Rodriguez CG; Sai H; Tobias J; Li Y; Wolfe MS; Shachaf C; Felsher D; Blacklow SC; Pear WS; Aster JC Genes Dev; 2006 Aug; 20(15):2096-109. PubMed ID: 16847353 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]