141 related articles for article (PubMed ID: 29023843)
1. Parameterization of the GPR119 Receptor Agonist AR231453.
Hamilton J; Kotsikorou E
J Comput Chem; 2018 Jan; 39(1):35-41. PubMed ID: 29023843
[TBL] [Abstract][Full Text] [Related]
2. Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119.
Hassing HA; Fares S; Larsen O; Pad H; Hauge M; Jones RM; Schwartz TW; Hansen HS; Rosenkilde MM
Biochem Pharmacol; 2016 Nov; 119():66-75. PubMed ID: 27569424
[TBL] [Abstract][Full Text] [Related]
3. A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release.
Chu ZL; Jones RM; He H; Carroll C; Gutierrez V; Lucman A; Moloney M; Gao H; Mondala H; Bagnol D; Unett D; Liang Y; Demarest K; Semple G; Behan DP; Leonard J
Endocrinology; 2007 Jun; 148(6):2601-9. PubMed ID: 17289847
[TBL] [Abstract][Full Text] [Related]
4. Stimulating β-cell replication and improving islet graft function by AR231453, A GPR119 agonist.
Gao J; Tian L; Weng G; O'Brien TD; Luo J; Guo Z
Transplant Proc; 2011 Nov; 43(9):3217-20. PubMed ID: 22099761
[TBL] [Abstract][Full Text] [Related]
5. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Semple G; Ren A; Fioravanti B; Pereira G; Calderon I; Choi K; Xiong Y; Shin YJ; Gharbaoui T; Sage CR; Morgan M; Xing C; Chu ZL; Leonard JN; Grottick AJ; Al-Shamma H; Liang Y; Demarest KT; Jones RM
Bioorg Med Chem Lett; 2011 May; 21(10):3134-41. PubMed ID: 21444206
[TBL] [Abstract][Full Text] [Related]
6. A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release.
Chu ZL; Carroll C; Alfonso J; Gutierrez V; He H; Lucman A; Pedraza M; Mondala H; Gao H; Bagnol D; Chen R; Jones RM; Behan DP; Leonard J
Endocrinology; 2008 May; 149(5):2038-47. PubMed ID: 18202141
[TBL] [Abstract][Full Text] [Related]
7. Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119.
Engelstoft MS; Norn C; Hauge M; Holliday ND; Elster L; Lehmann J; Jones RM; Frimurer TM; Schwartz TW
Br J Pharmacol; 2014 Dec; 171(24):5774-89. PubMed ID: 25117266
[TBL] [Abstract][Full Text] [Related]
8. Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa.
Tough IR; Forbes S; Herzog H; Jones RM; Schwartz TW; Cox HM
Endocrinology; 2018 Apr; 159(4):1704-1717. PubMed ID: 29471473
[TBL] [Abstract][Full Text] [Related]
9. Novel GPR119 agonist HD0471042 attenuated type 2 diabetes mellitus.
Ha TY; Kim YS; Kim CH; Choi HS; Yang J; Park SH; Kim DH; Rhee JK
Arch Pharm Res; 2014 May; 37(5):671-8. PubMed ID: 23897163
[TBL] [Abstract][Full Text] [Related]
10. β-Cell Inactivation of
Panaro BL; Flock GB; Campbell JE; Beaudry JL; Cao X; Drucker DJ
Diabetes; 2017 Jun; 66(6):1626-1635. PubMed ID: 28254842
[TBL] [Abstract][Full Text] [Related]
11. Activation of GPR119 by fatty acid agonists augments insulin release from clonal β-cells and isolated pancreatic islets and improves glucose tolerance in mice.
Moran BM; Abdel-Wahab YH; Flatt PR; McKillop AM
Biol Chem; 2014 Apr; 395(4):453-64. PubMed ID: 24323890
[TBL] [Abstract][Full Text] [Related]
12. Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening.
Norn C; Hauge M; Engelstoft MS; Kim SH; Lehmann J; Jones RM; Schwartz TW; Frimurer TM
Structure; 2015 Dec; 23(12):2377-2386. PubMed ID: 26526849
[TBL] [Abstract][Full Text] [Related]
13. Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion.
Yoshida S; Ohishi T; Matsui T; Shibasaki M
Biochem Biophys Res Commun; 2010 Sep; 400(3):437-41. PubMed ID: 20804735
[TBL] [Abstract][Full Text] [Related]
14. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice.
Bahirat UA; Shenoy RR; Goel RN; Nemmani KV
Eur J Pharmacol; 2017 Apr; 801():35-45. PubMed ID: 28274625
[TBL] [Abstract][Full Text] [Related]
15. [The role of pharmacology to produce firuglipel (DS-8500a), an orally available GPR119 agonist for type 2 diabetes mellitus].
Matsumoto K; Yoshitomi T; Shimada T
Nihon Yakurigaku Zasshi; 2018; 152(3):119-124. PubMed ID: 30185729
[TBL] [Abstract][Full Text] [Related]
16. AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes.
Yoshida S; Tanaka H; Oshima H; Yamazaki T; Yonetoku Y; Ohishi T; Matsui T; Shibasaki M
Biochem Biophys Res Commun; 2010 Oct; 400(4):745-51. PubMed ID: 20816753
[TBL] [Abstract][Full Text] [Related]
17. GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion.
Chepurny OG; Holz GG; Roe MW; Leech CA
Mol Endocrinol; 2016 Jun; 30(6):614-29. PubMed ID: 27082897
[TBL] [Abstract][Full Text] [Related]
18. GPR119 agonists: Novel therapeutic agents for type 2 diabetes mellitus.
Manaithiya A; Alam O; Sharma V; Javed Naim M; Mittal S; Khan IA
Bioorg Chem; 2021 Aug; 113():104998. PubMed ID: 34048996
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and structure-activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists.
Negoro K; Yonetoku Y; Moritomo A; Hayakawa M; Iikubo K; Yoshida S; Takeuchi M; Ohta M
Bioorg Med Chem; 2012 Nov; 20(21):6442-51. PubMed ID: 23010456
[TBL] [Abstract][Full Text] [Related]
20. Discovery of structurally novel, potent and orally efficacious GPR119 agonists.
Alper P; Azimioara M; Cow C; Mutnick D; Nikulin V; Michellys PY; Wang Z; Reding E; Paliotti M; Li J; Bao D; Zoll J; Kim Y; Zimmerman M; Groessel T; Tuntland T; Joseph SB; McNamara P; Seidel HM; Epple R
Bioorg Med Chem Lett; 2014 May; 24(10):2383-7. PubMed ID: 24751443
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
