BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 29024789)

  • 1. In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers.
    Niessen KV; Seeger T; Rappenglück S; Wein T; Höfner G; Wanner KT; Thiermann H; Worek F
    Toxicol Lett; 2018 Sep; 293():190-197. PubMed ID: 29024789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length.
    Niessen KV; Seeger T; Tattersall JE; Timperley CM; Bird M; Green C; Thiermann H; Worek F
    Chem Biol Interact; 2013 Dec; 206(3):545-54. PubMed ID: 24157926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro.
    Seeger T; Eichhorn M; Lindner M; Niessen KV; Tattersall JE; Timperley CM; Bird M; Green AC; Thiermann H; Worek F
    Toxicology; 2012 Apr; 294(2-3):80-4. PubMed ID: 22349640
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficacy of the antinicotinic compound MB327 against soman poisoning - Importance of experimental end point.
    Price ME; Whitmore CL; Tattersall JEH; Green AC; Rice H
    Toxicol Lett; 2018 Sep; 293():167-171. PubMed ID: 29127032
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning.
    Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
    Toxicol Lett; 2018 Sep; 293():149-156. PubMed ID: 29248576
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents.
    Bernauer T; Nitsche V; Kaiser J; Gertzen CGW; Höfner G; Niessen KV; Seeger T; Steinritz D; Worek F; Gohlke H; Wanner KT; Paintner FF
    Toxicol Lett; 2024 Jun; 397():151-162. PubMed ID: 38759939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig.
    Price ME; Docx CJ; Rice H; Fairhall SJ; Poole SJC; Bird M; Whiley L; Flint DP; Green AC; Timperley CM; Tattersall JEH
    Toxicol Lett; 2016 Feb; 244():154-160. PubMed ID: 26325216
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.
    Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
    Toxicol Lett; 2018 Sep; 293():157-166. PubMed ID: 29191791
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reversed-phase ion-pair chromatography-diode array detection of the bispyridinium compound MB327: plasma analysis of a potential novel antidote for the treatment of organophosphorus poisoning.
    John H; Mikler J; Worek F; Thiermann H
    Drug Test Anal; 2016 Feb; 8(2):154-63. PubMed ID: 26041012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist.
    Turner SR; Chad JE; Price M; Timperley CM; Bird M; Green AC; Tattersall JE
    Toxicol Lett; 2011 Sep; 206(1):105-11. PubMed ID: 21641979
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice.
    Kassa J; Pohanka M; Timperley CM; Bird M; Green AC; Tattersall JE
    Toxicol Mech Methods; 2016 Jun; 26(5):334-9. PubMed ID: 27097774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Assessment of false transmitters as treatments for nerve agent poisoning.
    Whitmore C; Lindsay CD; Bird M; Gore SJ; Rice H; Williams RL; Timperley CM; Green AC
    Toxicol Lett; 2020 Mar; 321():21-31. PubMed ID: 31830555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antidotal efficacy of pyridinium chloride derivatives against soman poisoning.
    Vrdoljak AL; Lovrić J; Radić B; Zlender V
    Basic Clin Pharmacol Toxicol; 2006 Jul; 99(1):17-21. PubMed ID: 16867165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of MB327 and oximes on rat intestinal smooth muscle function.
    Königer C; Worek F; Thiermann H; Wille T
    Chem Biol Interact; 2013 Jun; 204(1):1-5. PubMed ID: 23603452
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor.
    Nitsche V; Höfner G; Kaiser J; Gertzen CGW; Seeger T; Niessen KV; Steinritz D; Worek F; Gohlke H; Paintner FF; Wanner KT
    Toxicol Lett; 2024 Feb; 392():94-106. PubMed ID: 38216073
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity.
    Calić M; Vrdoljak AL; Radić B; Jelić D; Jun D; Kuca K; Kovarik Z
    Toxicology; 2006 Feb; 219(1-3):85-96. PubMed ID: 16332406
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling.
    Wein T; Wanner KT; Rappenglück S; Sichler S; Niessen KV; Seeger T; Worek F; Thiermann H
    Curr Comput Aided Drug Des; 2019; 15(1):104-109. PubMed ID: 29968541
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.
    Gorecki L; Korabecny J; Musilek K; Malinak D; Nepovimova E; Dolezal R; Jun D; Soukup O; Kuca K
    Arch Toxicol; 2016 Dec; 90(12):2831-2859. PubMed ID: 27582056
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice.
    Kassa J; Timperley CM; Bird M; Williams RL; Green AC; Tattersall JEH
    Basic Clin Pharmacol Toxicol; 2018 Apr; 122(4):429-435. PubMed ID: 29117635
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships.
    Amend N; Timperley CM; Bird M; Green AC; Worek F; Seeger T
    Toxicology; 2024 Mar; 503():153741. PubMed ID: 38311098
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.