BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 29027990)

  • 1. IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer.
    Wang D; Xu J; Liu B; He X; Zhou L; Hu X; Qiao F; Zhang A; Xu X; Zhang H; Wicha MS; Zhang L; Shao ZM; Liu S
    Cell Death Differ; 2018 Feb; 25(2):330-339. PubMed ID: 29027990
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL.
    Hubmann R; Schnabl S; Araghi M; Schmidl C; Rendeiro AF; Hilgarth M; Demirtas D; Ali F; Staber PB; Valent P; Zielinski C; Jäger U; Shehata M
    Cells; 2020 Jun; 9(6):. PubMed ID: 32570839
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
    Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
    Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.
    Fan X; Khaki L; Zhu TS; Soules ME; Talsma CE; Gul N; Koh C; Zhang J; Li YM; Maciaczyk J; Nikkhah G; Dimeco F; Piccirillo S; Vescovi AL; Eberhart CG
    Stem Cells; 2010 Jan; 28(1):5-16. PubMed ID: 19904829
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
    Schott AF; Landis MD; Dontu G; Griffith KA; Layman RM; Krop I; Paskett LA; Wong H; Dobrolecki LE; Lewis MT; Froehlich AM; Paranilam J; Hayes DF; Wicha MS; Chang JC
    Clin Cancer Res; 2013 Mar; 19(6):1512-24. PubMed ID: 23340294
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NOTCH3 expression is linked to breast cancer seeding and distant metastasis.
    Leontovich AA; Jalalirad M; Salisbury JL; Mills L; Haddox C; Schroeder M; Tuma A; Guicciardi ME; Zammataro L; Gambino MW; Amato A; Di Leonardo A; McCubrey J; Lange CA; Liu M; Haddad T; Goetz M; Boughey J; Sarkaria J; Wang L; Ingle JN; Galanis E; D'Assoro AB
    Breast Cancer Res; 2018 Sep; 20(1):105. PubMed ID: 30180881
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evodiamine suppresses Notch3 signaling in lung tumorigenesis via direct binding to γ-secretases.
    Yang X; Zhang Y; Huang Y; Wang Y; Qi X; Su T; Lu L
    Phytomedicine; 2020 Mar; 68():153176. PubMed ID: 32045841
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.
    Wang K; Zhang Q; Li D; Ching K; Zhang C; Zheng X; Ozeck M; Shi S; Li X; Wang H; Rejto P; Christensen J; Olson P
    Clin Cancer Res; 2015 Mar; 21(6):1487-96. PubMed ID: 25564152
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
    Choy L; Hagenbeek TJ; Solon M; French D; Finkle D; Shelton A; Venook R; Brauer MJ; Siebel CW
    Cancer Res; 2017 Mar; 77(6):1439-1452. PubMed ID: 28108512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.
    Clementz AG; Rogowski A; Pandya K; Miele L; Osipo C
    Breast Cancer Res; 2011 Jun; 13(3):R63. PubMed ID: 21679465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC.
    Frank SB; Berger PL; Ljungman M; Miranti CK
    J Cell Sci; 2017 Jun; 130(11):1952-1964. PubMed ID: 28446540
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Notch3 inhibits cell proliferation and tumorigenesis and predicts better prognosis in breast cancer through transactivating PTEN.
    Zhang YQ; Liang YK; Wu Y; Chen M; Chen WL; Li RH; Zeng YZ; Huang WH; Wu JD; Zeng D; Gao WL; Chen CF; Lin HY; Yang RQ; Zhu JW; Liu WL; Bai JW; Wei M; Wei XL; Zhang GJ
    Cell Death Dis; 2021 May; 12(6):502. PubMed ID: 34006834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.
    Papadakos KS; Bartoschek M; Rodriguez C; Gialeli C; Jin SB; Lendahl U; Pietras K; Blom AM
    Matrix Biol; 2019 Aug; 81():107-121. PubMed ID: 30502484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.
    Hsu EC; Kulp SK; Huang HL; Tu HJ; Salunke SB; Sullivan NJ; Sun D; Wicha MS; Shapiro CL; Chen CS
    Neoplasia; 2015 Jun; 17(6):497-508. PubMed ID: 26152358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Notch promotes radioresistance of glioma stem cells.
    Wang J; Wakeman TP; Lathia JD; Hjelmeland AB; Wang XF; White RR; Rich JN; Sullenger BA
    Stem Cells; 2010 Jan; 28(1):17-28. PubMed ID: 19921751
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer.
    Kondratyev M; Kreso A; Hallett RM; Girgis-Gabardo A; Barcelon ME; Ilieva D; Ware C; Majumder PK; Hassell JA
    Oncogene; 2012 Jan; 31(1):93-103. PubMed ID: 21666715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential combination therapy of ovarian cancer with cisplatin and γ-secretase inhibitor MK-0752.
    Chen X; Gong L; Ou R; Zheng Z; Chen J; Xie F; Huang X; Qiu J; Zhang W; Jiang Q; Yang Y; Zhu H; Shi Z; Yan X
    Gynecol Oncol; 2016 Mar; 140(3):537-44. PubMed ID: 26704638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.
    Zhang S; Chung WC; Miele L; Xu K
    Cancer Biol Ther; 2014 May; 15(5):633-42. PubMed ID: 24556651
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
    Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Notch Signaling in Breast Cancer: A Role in Drug Resistance.
    BeLow M; Osipo C
    Cells; 2020 Sep; 9(10):. PubMed ID: 33003540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.