284 related articles for article (PubMed ID: 29031197)
1. Mitochondrial dysfunction is responsible for fatty acid synthase inhibition-induced apoptosis in breast cancer cells by PdpaMn.
Wang Q; Du X; Zhou B; Li J; Lu W; Chen Q; Gao J
Biomed Pharmacother; 2017 Dec; 96():396-403. PubMed ID: 29031197
[TBL] [Abstract][Full Text] [Related]
2. PdpaMn inhibits fatty acid synthase-mediated glycolysis by down-regulating PI3K/Akt signaling pathway in breast cancer.
Okrah EA; Wang Q; Fu H; Chen Q; Gao J
Anticancer Drugs; 2020 Nov; 31(10):1046-1056. PubMed ID: 32649369
[TBL] [Abstract][Full Text] [Related]
3. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration.
Rossato FA; Zecchin KG; La Guardia PG; Ortega RM; Alberici LC; Costa RA; Catharino RR; Graner E; Castilho RF; Vercesi AE
PLoS One; 2014; 9(6):e101060. PubMed ID: 24964211
[TBL] [Abstract][Full Text] [Related]
4. Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis.
Goswami S; Sharma-Walia N
Oncotarget; 2016 Sep; 7(37):58953-58974. PubMed ID: 27270654
[TBL] [Abstract][Full Text] [Related]
5. Development of a Self-Assembled Nanoparticle Formulation of Orlistat, Nano-ORL, with Increased Cytotoxicity against Human Tumor Cell Lines.
Hill TK; Davis AL; Wheeler FB; Kelkar SS; Freund EC; Lowther WT; Kridel SJ; Mohs AM
Mol Pharm; 2016 Mar; 13(3):720-8. PubMed ID: 26824142
[TBL] [Abstract][Full Text] [Related]
6. Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells.
Lee JS; Lee MS; Oh WK; Sul JY
Biol Pharm Bull; 2009 Aug; 32(8):1427-32. PubMed ID: 19652385
[TBL] [Abstract][Full Text] [Related]
7. Fatty acid synthase inhibitor orlistat induces apoptosis in T cell lymphoma: role of cell survival regulatory molecules.
Kant S; Kumar A; Singh SM
Biochim Biophys Acta; 2012 Nov; 1820(11):1764-73. PubMed ID: 22877747
[TBL] [Abstract][Full Text] [Related]
8. The selective target of capsaicin on FASN expression and de novo fatty acid synthesis mediated through ROS generation triggers apoptosis in HepG2 cells.
Impheng H; Pongcharoen S; Richert L; Pekthong D; Srisawang P
PLoS One; 2014; 9(9):e107842. PubMed ID: 25255125
[TBL] [Abstract][Full Text] [Related]
9. Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer.
Bauerschlag DO; Maass N; Leonhardt P; Verburg FA; Pecks U; Zeppernick F; Morgenroth A; Mottaghy FM; Tolba R; Meinhold-Heerlein I; Bräutigam K
J Transl Med; 2015 May; 13():146. PubMed ID: 25947066
[TBL] [Abstract][Full Text] [Related]
10. A novel 7-azaisoindigo derivative-induced cancer cell apoptosis and mitochondrial dysfunction mediated by oxidative stress.
Xu JJ; Dai XM; Liu HL; Guo WJ; Gao J; Wang CH; Li WB; Yao QZ
J Appl Toxicol; 2011 Mar; 31(2):164-72. PubMed ID: 20865757
[TBL] [Abstract][Full Text] [Related]
11. Fatty acid synthase regulates the chemosensitivity of breast cancer cells to cisplatin-induced apoptosis.
Al-Bahlani S; Al-Lawati H; Al-Adawi M; Al-Abri N; Al-Dhahli B; Al-Adawi K
Apoptosis; 2017 Jun; 22(6):865-876. PubMed ID: 28386750
[TBL] [Abstract][Full Text] [Related]
12. Targeting fatty acid synthase in breast and endometrial cancer: An alternative to selective estrogen receptor modulators?
Lupu R; Menendez JA
Endocrinology; 2006 Sep; 147(9):4056-66. PubMed ID: 16809439
[TBL] [Abstract][Full Text] [Related]
13. CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.
Yang CR; Liao WS; Wu YH; Murugan K; Chen C; Chao JI
Toxicol Appl Pharmacol; 2013 Dec; 273(3):611-22. PubMed ID: 24128853
[TBL] [Abstract][Full Text] [Related]
14. Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
Lee KH; Lee MS; Cha EY; Sul JY; Lee JS; Kim JS; Park JB; Kim JY
Mol Med Rep; 2017 Apr; 15(4):2163-2173. PubMed ID: 28260110
[TBL] [Abstract][Full Text] [Related]
15. Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio.
Pan YX; Luo Z; Zhuo MQ; Wei CC; Chen GH; Song YF
Aquat Toxicol; 2018 Jun; 199():12-20. PubMed ID: 29604498
[TBL] [Abstract][Full Text] [Related]
16. Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer.
Giró-Perafita A; Palomeras S; Lum DH; Blancafort A; Viñas G; Oliveras G; Pérez-Bueno F; Sarrats A; Welm AL; Puig T
Clin Cancer Res; 2016 Sep; 22(18):4687-97. PubMed ID: 27106068
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxicity of Manganese (III) Complex in Human Breast Adenocarcinoma Cell Line Is Mediated by the Generation of Reactive Oxygen Species Followed by Mitochondrial Damage.
Al-Anbaky Q; Al-Karakooly Z; Kilaparty SP; Agrawal M; Albkuri YM; RanguMagar AB; Ghosh A; Ali N
Int J Toxicol; 2016 Nov; 35(6):672-682. PubMed ID: 27461214
[TBL] [Abstract][Full Text] [Related]
18. Mitochondrial apoptosis and curtailment of hypoxia-inducible factor-1α/fatty acid synthase: A dual edge perspective of gamma linolenic acid in ER+ mammary gland cancer.
Roy S; Singh M; Rawat A; Kumar D; Kaithwas G
Cell Biochem Funct; 2020 Jul; 38(5):591-603. PubMed ID: 32207176
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
Lupu R; Menendez JA
Curr Pharm Biotechnol; 2006 Dec; 7(6):483-93. PubMed ID: 17168665
[TBL] [Abstract][Full Text] [Related]
20. NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition.
Cui Y; Xing P; Wang Y; Liu M; Qiu L; Ying G; Li B
Oncotarget; 2017 May; 8(20):32576-32585. PubMed ID: 28427229
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]