BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 29036362)

  • 1. CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.
    Kaur S; Ramdzan ZM; Guiot MC; Li L; Leduy L; Ramotar D; Sabri S; Abdulkarim B; Nepveu A
    Neuro Oncol; 2018 Mar; 20(4):484-493. PubMed ID: 29036362
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CUT Domains Stimulate Pol β Enzymatic Activities to Accelerate Completion of Base Excision Repair.
    Ramdzan ZM; Vickridge E; Li L; Faraco CCF; Djerir B; Leduy L; Maréchal A; Nepveu A
    J Mol Biol; 2021 Feb; 433(4):166806. PubMed ID: 33450246
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APE1/REF-1 down-regulation enhances the cytotoxic effects of temozolomide in a resistant glioblastoma cell line.
    Montaldi AP; Godoy PR; Sakamoto-Hojo ET
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():19-29. PubMed ID: 26520369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
    Silber JR; Bobola MS; Blank A; Schoeler KD; Haroldson PD; Huynh MB; Kolstoe DD
    Clin Cancer Res; 2002 Sep; 8(9):3008-18. PubMed ID: 12231548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNA repair function of CUX1 contributes to radioresistance.
    Ramdzan ZM; Ginjala V; Pinder JB; Chung D; Donovan CM; Kaur S; Leduy L; Dellaire G; Ganesan S; Nepveu A
    Oncotarget; 2017 Mar; 8(12):19021-19038. PubMed ID: 28147323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
    Bapat A; Glass LS; Luo M; Fishel ML; Long EC; Georgiadis MM; Kelley MR
    J Pharmacol Exp Ther; 2010 Sep; 334(3):988-98. PubMed ID: 20504914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.
    Kaur S; Coulombe Y; Ramdzan ZM; Leduy L; Masson JY; Nepveu A
    J Biol Chem; 2016 Oct; 291(43):22769-22780. PubMed ID: 27590341
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma.
    Xie J; Zhang L; Li M; Du J; Zhou L; Yang S; Zeng L; Li Z; Wang G; Wang D
    BMC Cancer; 2014 Jan; 14():11. PubMed ID: 24400589
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
    Ramdzan ZM; Vadnais C; Pal R; Vandal G; Cadieux C; Leduy L; Davoudi S; Hulea L; Yao L; Karnezis AN; Paquet M; Dankort D; Nepveu A
    PLoS Biol; 2014 Mar; 12(3):e1001807. PubMed ID: 24618719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts.
    Ramdzan ZM; Pal R; Kaur S; Leduy L; Bérubé G; Davoudi S; Vadnais C; Nepveu A
    Oncotarget; 2015 Feb; 6(6):3613-26. PubMed ID: 25682875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
    Pal R; Ramdzan ZM; Kaur S; Duquette PM; Marcotte R; Leduy L; Davoudi S; Lamarche-Vane N; Iulianella A; Nepveu A
    J Biol Chem; 2015 Sep; 290(37):22520-31. PubMed ID: 26221032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CUX1: a modulator of tumour aggressiveness in pancreatic neuroendocrine neoplasms.
    Krug S; Kühnemuth B; Griesmann H; Neesse A; Mühlberg L; Boch M; Kortenhaus J; Fendrich V; Wiese D; Sipos B; Friemel J; Gress TM; Michl P
    Endocr Relat Cancer; 2014; 21(6):879-90. PubMed ID: 25248790
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma.
    Ströbel T; Madlener S; Tuna S; Vose S; Lagerweij T; Wurdinger T; Vierlinger K; Wöhrer A; Price BD; Demple B; Saydam O; Saydam N
    Sci Rep; 2017 Aug; 7(1):9674. PubMed ID: 28852018
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death.
    He Y; Roos WP; Wu Q; Hofmann TG; Kaina B
    Mol Cancer Res; 2019 May; 17(5):1129-1141. PubMed ID: 30796178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.
    Bobola MS; Finn LS; Ellenbogen RG; Geyer JR; Berger MS; Braga JM; Meade EH; Gross ME; Silber JR
    Clin Cancer Res; 2005 Oct; 11(20):7405-14. PubMed ID: 16243814
    [TBL] [Abstract][Full Text] [Related]  

  • 17. APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC.
    Malfatti MC; Gerratana L; Dalla E; Isola M; Damante G; Di Loreto C; Puglisi F; Tell G
    J Exp Clin Cancer Res; 2019 Jul; 38(1):309. PubMed ID: 31307523
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of PI3K Pathway in Glioma Cell Resistance to Temozolomide Treatment.
    Zając A; Sumorek-Wiadro J; Langner E; Wertel I; Maciejczyk A; Pawlikowska-Pawlęga B; Pawelec J; Wasiak M; Hułas-Stasiak M; Bądziul D; Rzeski W; Reichert M; Jakubowicz-Gil J
    Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34068110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.
    Rai G; Vyjayanti VN; Dorjsuren D; Simeonov A; Jadhav A; Wilson DM; Maloney DJ
    J Med Chem; 2012 Apr; 55(7):3101-12. PubMed ID: 22455312
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GADD45A plays a protective role against temozolomide treatment in glioblastoma cells.
    Wang HH; Chang TY; Lin WC; Wei KC; Shin JW
    Sci Rep; 2017 Aug; 7(1):8814. PubMed ID: 28821714
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.