514 related articles for article (PubMed ID: 29039574)
1. TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK.
Witte D; Bartscht T; Kaufmann R; Pries R; Settmacher U; Lehnert H; Ungefroren H
Oncol Rep; 2017 Dec; 38(6):3693-3701. PubMed ID: 29039574
[TBL] [Abstract][Full Text] [Related]
2. Nox4-derived ROS signaling contributes to TGF-β-induced epithelial-mesenchymal transition in pancreatic cancer cells.
Hiraga R; Kato M; Miyagawa S; Kamata T
Anticancer Res; 2013 Oct; 33(10):4431-8. PubMed ID: 24123012
[TBL] [Abstract][Full Text] [Related]
3. Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase.
Groth S; Schulze M; Kalthoff H; Fändrich F; Ungefroren H
J Biol Chem; 2005 Sep; 280(39):33190-9. PubMed ID: 16051607
[TBL] [Abstract][Full Text] [Related]
4. RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species.
Manickam N; Patel M; Griendling KK; Gorin Y; Barnes JL
Am J Physiol Renal Physiol; 2014 Jul; 307(2):F159-71. PubMed ID: 24872317
[TBL] [Abstract][Full Text] [Related]
5. Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1.
Ungefroren H; Groth S; Sebens S; Lehnert H; Gieseler F; Fändrich F
Mol Cancer; 2011 May; 10():67. PubMed ID: 21624123
[TBL] [Abstract][Full Text] [Related]
6. Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b.
Witte D; Otterbein H; Förster M; Giehl K; Zeiser R; Lehnert H; Ungefroren H
Sci Rep; 2017 Dec; 7(1):17313. PubMed ID: 29229918
[TBL] [Abstract][Full Text] [Related]
7. Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling.
Ungefroren H; Sebens S; Giehl K; Helm O; Groth S; Fändrich F; Röcken C; Sipos B; Lehnert H; Gieseler F
Oncotarget; 2014 Jan; 5(1):277-90. PubMed ID: 24378395
[TBL] [Abstract][Full Text] [Related]
8. Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.
Liu RM; Choi J; Wu JH; Gaston Pravia KA; Lewis KM; Brand JD; Mochel NS; Krzywanski DM; Lambeth JD; Hagood JS; Forman HJ; Thannickal VJ; Postlethwait EM
J Biol Chem; 2010 May; 285(21):16239-47. PubMed ID: 20228065
[TBL] [Abstract][Full Text] [Related]
9. Glucocorticoids induce apoptosis and matrix metalloproteinase-13 expression in chondrocytes through the NOX4/ROS/p38 MAPK pathway.
Huang Y; Cai GQ; Peng JP; Shen C
J Steroid Biochem Mol Biol; 2018 Jul; 181():52-62. PubMed ID: 29526705
[TBL] [Abstract][Full Text] [Related]
10. NADPH oxidase 4 contributes to connective tissue growth factor expression through Smad3-dependent signaling pathway.
Liu XH; Zhang QY; Pan LL; Liu SY; Xu P; Luo XL; Zou SL; Xin H; Qu LF; Zhu YZ
Free Radic Biol Med; 2016 May; 94():174-84. PubMed ID: 26945889
[TBL] [Abstract][Full Text] [Related]
11. Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells.
Sturrock A; Cahill B; Norman K; Huecksteadt TP; Hill K; Sanders K; Karwande SV; Stringham JC; Bull DA; Gleich M; Kennedy TP; Hoidal JR
Am J Physiol Lung Cell Mol Physiol; 2006 Apr; 290(4):L661-L673. PubMed ID: 16227320
[TBL] [Abstract][Full Text] [Related]
12. Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.
Boudreau HE; Casterline BW; Burke DJ; Leto TL
Br J Cancer; 2014 May; 110(10):2569-82. PubMed ID: 24714748
[TBL] [Abstract][Full Text] [Related]
13. Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4.
Hotta Y; Uchiyama K; Takagi T; Kashiwagi S; Nakano T; Mukai R; Toyokawa Y; Yasuda T; Ueda T; Suyama Y; Murakami T; Tanaka M; Majima A; Doi T; Hirai Y; Mizushima K; Morita M; Higashimura Y; Inoue K; Fukui A; Okayama T; Katada K; Kamada K; Handa O; Ishikawa T; Naito Y; Itoh Y
Biochem Biophys Res Commun; 2018 Nov; 506(3):557-562. PubMed ID: 30361098
[TBL] [Abstract][Full Text] [Related]
14. Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells.
Ungefroren H; Sebens S; Groth S; Gieseler F; Fändrich F
Int J Oncol; 2011 Mar; 38(3):797-805. PubMed ID: 21225226
[TBL] [Abstract][Full Text] [Related]
15. NRF2 level is negatively correlated with TGF-β1-induced lung cancer motility and migration via NOX4-ROS signaling.
Ryu D; Lee JH; Kwak MK
Arch Pharm Res; 2020 Dec; 43(12):1297-1310. PubMed ID: 33242180
[TBL] [Abstract][Full Text] [Related]
16. Diosmetin prevents TGF-β1-induced epithelial-mesenchymal transition via ROS/MAPK signaling pathways.
Ge A; Ma Y; Liu YN; Li YS; Gu H; Zhang JX; Wang QX; Zeng XN; Huang M
Life Sci; 2016 May; 153():1-8. PubMed ID: 27101925
[TBL] [Abstract][Full Text] [Related]
17. TGF-β Signal Transduction in Pancreatic Carcinoma Cells is Sensitive to Inhibition by the Src Tyrosine Kinase Inhibitor AZM475271.
Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnert H; Ungefroren H
Anticancer Agents Med Chem; 2017; 17(7):966-972. PubMed ID: 27671303
[TBL] [Abstract][Full Text] [Related]
18. Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.
Tod J; Hanley CJ; Morgan MR; Rucka M; Mellows T; Lopez MA; Kiely P; Moutasim KA; Frampton SJ; Sabnis D; Fine DR; Johnson C; Marshall JF; Scita G; Jenei V; Thomas GJ
J Pathol; 2017 Sep; 243(1):37-50. PubMed ID: 28608476
[TBL] [Abstract][Full Text] [Related]
19. TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes.
Chiu C; Maddock DA; Zhang Q; Souza KP; Townsend AR; Wan Y
Int J Mol Med; 2001 Sep; 8(3):251-5. PubMed ID: 11494050
[TBL] [Abstract][Full Text] [Related]
20. RAC1B: A Guardian of the Epithelial Phenotype and Protector Against Epithelial-Mesenchymal Transition.
Zinn R; Otterbein H; Lehnert H; Ungefroren H
Cells; 2019 Dec; 8(12):. PubMed ID: 31817229
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
