327 related articles for article (PubMed ID: 29040522)
1. Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal.
Kang SS; Kurti A; Baker KE; Liu CC; Colonna M; Ulrich JD; Holtzman DM; Bu G; Fryer JD
Hum Mol Genet; 2018 Jan; 27(2):211-223. PubMed ID: 29040522
[TBL] [Abstract][Full Text] [Related]
2. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
McQuade A; Kang YJ; Hasselmann J; Jairaman A; Sotelo A; Coburn M; Shabestari SK; Chadarevian JP; Fote G; Tu CH; Danhash E; Silva J; Martinez E; Cotman C; Prieto GA; Thompson LM; Steffan JS; Smith I; Davtyan H; Cahalan M; Cho H; Blurton-Jones M
Nat Commun; 2020 Oct; 11(1):5370. PubMed ID: 33097708
[TBL] [Abstract][Full Text] [Related]
3. Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice.
Jadhav VS; Lin PBC; Pennington T; Di Prisco GV; Jannu AJ; Xu G; Moutinho M; Zhang J; Atwood BK; Puntambekar SS; Bissel SJ; Oblak AL; Landreth GE; Lamb BT
Mol Neurodegener; 2020 Oct; 15(1):62. PubMed ID: 33115519
[TBL] [Abstract][Full Text] [Related]
4. Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice.
Qu W; Li L
J Neurosci; 2020 Dec; 40(50):9552-9563. PubMed ID: 33139402
[TBL] [Abstract][Full Text] [Related]
5. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.
Zheng H; Liu CC; Atagi Y; Chen XF; Jia L; Yang L; He W; Zhang X; Kang SS; Rosenberry TL; Fryer JD; Zhang YW; Xu H; Bu G
Neurobiol Aging; 2016 Jun; 42():132-41. PubMed ID: 27143430
[TBL] [Abstract][Full Text] [Related]
6. Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease.
Jiang T; Tan L; Zhu XC; Zhang QQ; Cao L; Tan MS; Gu LZ; Wang HF; Ding ZZ; Zhang YD; Yu JT
Neuropsychopharmacology; 2014 Dec; 39(13):2949-62. PubMed ID: 25047746
[TBL] [Abstract][Full Text] [Related]
7. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice.
Jiang T; Zhang YD; Chen Q; Gao Q; Zhu XC; Zhou JS; Shi JQ; Lu H; Tan L; Yu JT
Neuropharmacology; 2016 Jun; 105():196-206. PubMed ID: 26802771
[TBL] [Abstract][Full Text] [Related]
8. TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.
Zheng H; Jia L; Liu CC; Rong Z; Zhong L; Yang L; Chen XF; Fryer JD; Wang X; Zhang YW; Xu H; Bu G
J Neurosci; 2017 Feb; 37(7):1772-1784. PubMed ID: 28077724
[TBL] [Abstract][Full Text] [Related]
9. Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model.
Beckmann N; Neuhaus A; Zurbruegg S; Volkmer P; Patino C; Joller S; Feuerbach D; Doelemeyer A; Schweizer T; Rudin S; Neumann U; Berth R; Frieauff W; Gasparini F; Shimshek DR
J Neuroinflammation; 2023 Feb; 20(1):29. PubMed ID: 36755323
[TBL] [Abstract][Full Text] [Related]
10. TREM2 regulates microglial phagocytosis of synapses in innate immune tolerance.
Meng J; Han L; Xu H; Zhang L; Liu Z; Zhou Y; Zhang X; Luo H; Zhang YW
Int Immunopharmacol; 2024 Jan; 127():111445. PubMed ID: 38147777
[TBL] [Abstract][Full Text] [Related]
11. Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice.
Jiang T; Tan L; Zhu XC; Zhou JS; Cao L; Tan MS; Wang HF; Chen Q; Zhang YD; Yu JT
Neurobiol Aging; 2015 Dec; 36(12):3176-3186. PubMed ID: 26364736
[TBL] [Abstract][Full Text] [Related]
12. Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation.
Zhou J; Yu W; Zhang M; Tian X; Li Y; Lü Y
Neurochem Res; 2019 May; 44(5):1138-1151. PubMed ID: 30756214
[TBL] [Abstract][Full Text] [Related]
13. A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Carrasquillo MM; Allen M; Burgess JD; Wang X; Strickland SL; Aryal S; Siuda J; Kachadoorian ML; Medway C; Younkin CS; Nair A; Wang C; Chanana P; Serie D; Nguyen T; Lincoln S; Malphrus KG; Morgan K; Golde TE; Price ND; White CC; De Jager PL; Bennett DA; Asmann YW; Crook JE; Petersen RC; Graff-Radford NR; Dickson DW; Younkin SG; Ertekin-Taner N
Alzheimers Dement; 2017 Jun; 13(6):663-673. PubMed ID: 27939925
[TBL] [Abstract][Full Text] [Related]
14. TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.
Leyns CEG; Ulrich JD; Finn MB; Stewart FR; Koscal LJ; Remolina Serrano J; Robinson GO; Anderson E; Colonna M; Holtzman DM
Proc Natl Acad Sci U S A; 2017 Oct; 114(43):11524-11529. PubMed ID: 29073081
[TBL] [Abstract][Full Text] [Related]
15. Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.
Li X; Montine KS; Keene CD; Montine TJ
FASEB J; 2015 May; 29(5):1754-62. PubMed ID: 25593125
[TBL] [Abstract][Full Text] [Related]
16. The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S; Madore C; Cialic R; Baufeld C; Calcagno N; El Fatimy R; Beckers L; O'Loughlin E; Xu Y; Fanek Z; Greco DJ; Smith ST; Tweet G; Humulock Z; Zrzavy T; Conde-Sanroman P; Gacias M; Weng Z; Chen H; Tjon E; Mazaheri F; Hartmann K; Madi A; Ulrich JD; Glatzel M; Worthmann A; Heeren J; Budnik B; Lemere C; Ikezu T; Heppner FL; Litvak V; Holtzman DM; Lassmann H; Weiner HL; Ochando J; Haass C; Butovsky O
Immunity; 2017 Sep; 47(3):566-581.e9. PubMed ID: 28930663
[TBL] [Abstract][Full Text] [Related]
17. Differential modulation of TREM2 protein during postnatal brain development in mice.
Chertoff M; Shrivastava K; Gonzalez B; Acarin L; Giménez-Llort L
PLoS One; 2013; 8(8):e72083. PubMed ID: 23977213
[TBL] [Abstract][Full Text] [Related]
18. Triggering receptor expressed on myeloid cells 2 activation downregulates toll-like receptor 4 expression and ameliorates cognitive impairment in the Aβ
Qin Z; Gu M; Zhou J; Zhang W; Zhao N; Lü Y; Yu W
Synapse; 2020 Oct; 74(10):e22161. PubMed ID: 32412103
[TBL] [Abstract][Full Text] [Related]
19. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.
Melchior B; Garcia AE; Hsiung BK; Lo KM; Doose JM; Thrash JC; Stalder AK; Staufenbiel M; Neumann H; Carson MJ
ASN Neuro; 2010 Jul; 2(3):e00037. PubMed ID: 20640189
[TBL] [Abstract][Full Text] [Related]
20. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain.
Carbajosa G; Malki K; Lawless N; Wang H; Ryder JW; Wozniak E; Wood K; Mein CA; Dobson RJB; Collier DA; O'Neill MJ; Hodges AK; Newhouse SJ
Neurobiol Aging; 2018 Sep; 69():151-166. PubMed ID: 29906661
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]