BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

511 related articles for article (PubMed ID: 29042512)

  • 1. In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.
    Carbone CB; Kern N; Fernandes RA; Hui E; Su X; Garcia KC; Vale RD
    Proc Natl Acad Sci U S A; 2017 Oct; 114(44):E9338-E9345. PubMed ID: 29042512
    [TBL] [Abstract][Full Text] [Related]  

  • 2. T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.
    Choudhuri K; Wiseman D; Brown MH; Gould K; van der Merwe PA
    Nature; 2005 Jul; 436(7050):578-82. PubMed ID: 16049493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. How does T cell receptor clustering impact on signal transduction?
    Goyette J; Nieves DJ; Ma Y; Gaus K
    J Cell Sci; 2019 Feb; 132(4):. PubMed ID: 30745330
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.
    Choudhuri K; Parker M; Milicic A; Cole DK; Shaw MK; Sewell AK; Stewart-Jones G; Dong T; Gould KG; van der Merwe PA
    J Biol Chem; 2009 Sep; 284(38):26096-105. PubMed ID: 19628870
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Initiation of T cell signaling by CD45 segregation at 'close contacts'.
    Chang VT; Fernandes RA; Ganzinger KA; Lee SF; Siebold C; McColl J; Jönsson P; Palayret M; Harlos K; Coles CH; Jones EY; Lui Y; Huang E; Gilbert RJC; Klenerman D; Aricescu AR; Davis SJ
    Nat Immunol; 2016 May; 17(5):574-582. PubMed ID: 26998761
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation.
    Al-Aghbar MA; Chu YS; Chen BM; Roffler SR
    Front Immunol; 2018; 9():713. PubMed ID: 29686683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination.
    Pielak RM; O'Donoghue GP; Lin JJ; Alfieri KN; Fay NC; Low-Nam ST; Groves JT
    Proc Natl Acad Sci U S A; 2017 Nov; 114(46):12190-12195. PubMed ID: 29087297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition.
    Jung Y; Wen L; Altman A; Ley K
    Nat Commun; 2021 Jun; 12(1):3872. PubMed ID: 34162836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biophysical mechanism of T-cell receptor triggering in a reconstituted system.
    James JR; Vale RD
    Nature; 2012 Jul; 487(7405):64-9. PubMed ID: 22763440
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nanoscale kinetic segregation of TCR and CD45 in engaged microvilli facilitates early T cell activation.
    Razvag Y; Neve-Oz Y; Sajman J; Reches M; Sherman E
    Nat Commun; 2018 Feb; 9(1):732. PubMed ID: 29467364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling.
    He X; Woodford-Thomas TA; Johnson KG; Shah DD; Thomas ML
    Eur J Immunol; 2002 Sep; 32(9):2578-87. PubMed ID: 12207342
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition.
    Li K; Yuan Z; Lyu J; Ahn E; Davis SJ; Ahmed R; Zhu C
    Nat Commun; 2021 May; 12(1):2746. PubMed ID: 33980853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The phosphatase domains of CD45 are required for ligand induced T-cell receptor downregulation.
    Kastrup J; Lauritsen JP; Menné C; Dietrich J; Geisler C
    Scand J Immunol; 2000 May; 51(5):491-6. PubMed ID: 10792841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.
    Leitenberg D; Novak TJ; Farber D; Smith BR; Bottomly K
    J Exp Med; 1996 Jan; 183(1):249-59. PubMed ID: 8551228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of T cell function by TCR/pMHC binding kinetics.
    Carreño LJ; González PA; Kalergis AM
    Immunobiology; 2006; 211(1-2):47-64. PubMed ID: 16446170
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor.
    Cordoba SP; Choudhuri K; Zhang H; Bridge M; Basat AB; Dustin ML; van der Merwe PA
    Blood; 2013 May; 121(21):4295-302. PubMed ID: 23580664
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation.
    Leitenberg D; Boutin Y; Lu DD; Bottomly K
    Immunity; 1999 Jun; 10(6):701-11. PubMed ID: 10403645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase.
    Desai DM; Sap J; Schlessinger J; Weiss A
    Cell; 1993 May; 73(3):541-54. PubMed ID: 8490965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events.
    Lin JJY; Low-Nam ST; Alfieri KN; McAffee DB; Fay NC; Groves JT
    Sci Signal; 2019 Jan; 12(564):. PubMed ID: 30647147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.
    Crites TJ; Padhan K; Muller J; Krogsgaard M; Gudla PR; Lockett SJ; Varma R
    J Immunol; 2014 Jul; 193(1):56-67. PubMed ID: 24860189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.