These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
183 related articles for article (PubMed ID: 29045865)
1. Cooperative Nucleotide Binding in Hsp90 and Its Regulation by Aha1. Wortmann P; Götz M; Hugel T Biophys J; 2017 Oct; 113(8):1711-1718. PubMed ID: 29045865 [TBL] [Abstract][Full Text] [Related]
2. Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90. Hessling M; Richter K; Buchner J Nat Struct Mol Biol; 2009 Mar; 16(3):287-93. PubMed ID: 19234467 [TBL] [Abstract][Full Text] [Related]
3. Asymmetric activation of the hsp90 dimer by its cochaperone aha1. Retzlaff M; Hagn F; Mitschke L; Hessling M; Gugel F; Kessler H; Richter K; Buchner J Mol Cell; 2010 Feb; 37(3):344-54. PubMed ID: 20159554 [TBL] [Abstract][Full Text] [Related]
4. Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle. Li J; Richter K; Reinstein J; Buchner J Nat Struct Mol Biol; 2013 Mar; 20(3):326-31. PubMed ID: 23396352 [TBL] [Abstract][Full Text] [Related]
5. The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis. Mickler M; Hessling M; Ratzke C; Buchner J; Hugel T Nat Struct Mol Biol; 2009 Mar; 16(3):281-6. PubMed ID: 19234469 [TBL] [Abstract][Full Text] [Related]
6. Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors. Mollapour M; Bourboulia D; Beebe K; Woodford MR; Polier S; Hoang A; Chelluri R; Li Y; Guo A; Lee MJ; Fotooh-Abadi E; Khan S; Prince T; Miyajima N; Yoshida S; Tsutsumi S; Xu W; Panaretou B; Stetler-Stevenson WG; Bratslavsky G; Trepel JB; Prodromou C; Neckers L Mol Cell; 2014 Jan; 53(2):317-29. PubMed ID: 24462205 [TBL] [Abstract][Full Text] [Related]
7. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle. Siligardi G; Hu B; Panaretou B; Piper PW; Pearl LH; Prodromou C J Biol Chem; 2004 Dec; 279(50):51989-98. PubMed ID: 15466438 [TBL] [Abstract][Full Text] [Related]
8. A chemical compound inhibiting the Aha1-Hsp90 chaperone complex. Stiegler SC; Rübbelke M; Korotkov VS; Weiwad M; John C; Fischer G; Sieber SA; Sattler M; Buchner J J Biol Chem; 2017 Oct; 292(41):17073-17083. PubMed ID: 28851842 [TBL] [Abstract][Full Text] [Related]
9. The Mechanism of Hsp90 ATPase Stimulation by Aha1. Wolmarans A; Lee B; Spyracopoulos L; LaPointe P Sci Rep; 2016 Sep; 6():33179. PubMed ID: 27615124 [TBL] [Abstract][Full Text] [Related]
10. The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation. Mercier R; Wolmarans A; Schubert J; Neuweiler H; Johnson JL; LaPointe P Nat Commun; 2019 Mar; 10(1):1273. PubMed ID: 30894538 [TBL] [Abstract][Full Text] [Related]
11. Heat shock protein 90's mechanochemical cycle is dominated by thermal fluctuations. Ratzke C; Berkemeier F; Hugel T Proc Natl Acad Sci U S A; 2012 Jan; 109(1):161-6. PubMed ID: 22184223 [TBL] [Abstract][Full Text] [Related]
12. Large Rotation of the N-terminal Domain of Hsp90 Is Important for Interaction with Some but Not All Client Proteins. Daturpalli S; Knieß RA; Lee CT; Mayer MP J Mol Biol; 2017 May; 429(9):1406-1423. PubMed ID: 28363677 [TBL] [Abstract][Full Text] [Related]
13. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery. Meyer P; Prodromou C; Liao C; Hu B; Roe SM; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH EMBO J; 2004 Mar; 23(6):1402-10. PubMed ID: 15039704 [TBL] [Abstract][Full Text] [Related]
14. Dynamic Aha1 co-chaperone binding to human Hsp90. Oroz J; Blair LJ; Zweckstetter M Protein Sci; 2019 Sep; 28(9):1545-1551. PubMed ID: 31299134 [TBL] [Abstract][Full Text] [Related]
15. Controlling protein function by fine-tuning conformational flexibility. Schmid S; Hugel T Elife; 2020 Jul; 9():. PubMed ID: 32697684 [TBL] [Abstract][Full Text] [Related]
16. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Ali MM; Roe SM; Vaughan CK; Meyer P; Panaretou B; Piper PW; Prodromou C; Pearl LH Nature; 2006 Apr; 440(7087):1013-7. PubMed ID: 16625188 [TBL] [Abstract][Full Text] [Related]
17. Hsp90 cochaperone Aha1 is a negative regulator of the Saccharomyces MAL activator and acts early in the chaperone activation pathway. Ran F; Gadura N; Michels CA J Biol Chem; 2010 Apr; 285(18):13850-62. PubMed ID: 20177068 [TBL] [Abstract][Full Text] [Related]
18. Aha1 regulates Hsp90's conformation and function in a stoichiometry-dependent way. Mondol T; Silbermann LM; Schimpf J; Vollmar L; Hermann B; Tych KK; Hugel T Biophys J; 2023 Sep; 122(17):3458-3468. PubMed ID: 37515325 [TBL] [Abstract][Full Text] [Related]
19. Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone. Street TO; Lavery LA; Agard DA Mol Cell; 2011 Apr; 42(1):96-105. PubMed ID: 21474071 [TBL] [Abstract][Full Text] [Related]
20. Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Mollapour M; Tsutsumi S; Truman AW; Xu W; Vaughan CK; Beebe K; Konstantinova A; Vourganti S; Panaretou B; Piper PW; Trepel JB; Prodromou C; Pearl LH; Neckers L Mol Cell; 2011 Mar; 41(6):672-81. PubMed ID: 21419342 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]